distribution — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2225	4-Hydroxyantipyrine		COX
	4-Hydroxyantipyrine is formed during oxidative deamination of aminopyrine.		COX
T3875	CLINODISIDE A		Others
	Clinodiside A in rats with one compartment open model into the body, rapid distribution, elimination rate.		Others
T35337L	Teduglutide acetate		Glucagon Receptor
	Teduglutide acetate, a GLP-2 analogue, maximizes small intestinal mucosal hypertrophy. Teduglutide acetate partially restores small intestinal epithelial function through an altered distribution of claudin-10, facilitati...		Glucagon Receptor
T3S0057	Dihydrochelerythrine	12,13-Dihydrochelerythrine	Antifungal
	1. Dihydrochelerythrine (12,13-Dihydrochelerythrine) is nontoxic up to 5μM concentration. 2. Dihydrochelerythrine has antifungal activity against pathogenic plant fungi. 3. Dihydrochelerythrine has potential application ...		Antifungal
T9897	7-Methoxy-1-naphthaleneacetic acid		Others
	7-Methoxy-1-naphthaleneacetic acid is an inhibitor of auxin action in plants. 7-Methoxy-1-naphthaleneacetic acid inhibits polar auxin transport and tropic responses associated with asymmetric auxin distribution in Arabid...		Others
T4685	INOSINIC ACID	Inosine 5′-monophosphate,IMP,I-5'-P	Endogenous Metabolite
	Inosinic acid (IMP) is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. Inosinic acid is a nucleotide present in muscle and other tissues. It is formed by the...		Endogenous Metabolite
TN2080	Pinoresinol	(+)-Pinoresinol	Apoptosis , NF-κB , CDK , p53
	Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative st...		Apoptosis , NF-κB , CDK , p53
T14835	BTRX-335140	CYM-53093	Opioid Receptor
	BTRX-335140 (CYM-53093) is a potent and selective, orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively. BTRX-335140...		Opioid Receptor
T6S2227	Spinosin	Flavoayamenin	Others
	1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammato...		Others
T13247	UK-101	UK101,UK 101	Proteasome
	UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μM. UK-101 has a 144-fold and 10-fold higher affinity for β1i ...		Proteasome
T1083L	Theophylline monohydrate	Quibron	HDAC , PDE , Adenosine Receptor
	Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Theophylline monohydrate is a ...		HDAC , PDE , Adenosine Receptor
T34166	PROTAC_ERRalpha
	PROTAC_ERRalpha is a proteolysis targeting chimeras (PROTAC) which provides broad tissue distribution and knockdown of the targeted ERRalpha protein in tumor xenografts.
T33392	MIP-1095 I-123	123-I-MIP-1095,(123I)MIP 1095
	MIP-1095 I-123, as a radiotracer, is under investigation in clinical trial NCT00712829 (Evaluating the Safety, Pharmacokinetics, Tissue Distribution, Metabolism and Dosimetry of Two Prostate Cancer Imaging Agents).
T24924	Umibecestat HCl (1387560-01-1 free base)	CNP 520,Umibecestat HCl,Umibecestat hydrochloride,CNP520,CNP-520
	Umibecestat is a beta-secretase inhibitor. CNP520 has a selectivity, pharmacodynamics, and distribution profile suitable for AD prevention studies.
T32082	Histidyl-aspartyl-glutamyl-leucine	His-asp-glu-leu,Hdel sequence
	HDEL intracellular distribution is characteristic of plant endoplasmic reticulum (ER).
T26230	Stilbamidine dihydrochloride	NSC 35605,NCI 174
	Stilbamidine dihydrochloride is a blocker of neuromuscular transmission and axonal conduction used to study the distribution of the drug in the organs and tissues of rats following intravenous injection.
T82238	HAPSBC
	HAPSBC, an S-benzyl iron chelator, modulates the intracellular distribution of ^59Fe [1].
T14289	Anguizole		Others
	Anguizole, a small molecule, effectively inhibits Hepatitis C Virus (HCV) replication by modifying the subcellular distribution of NS4B. It demonstrates its potency with an IC50 value, highlighting its specific target ac...		Others
T16993	Taribavirin		Others
	Taribavirin is an orally active inosine monophosphate dehydrogenase inhibitor. Taribavirin is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cel...		Others
T29154	WB403	WB-403,WB 403
	WB403 is a TGR5 activator. WB403 significantly decreases fasting blood glucose, postprandial blood glucose and HbA1c, improves glucose tolerance in type 2 diabetic mice. WB403 increases pancreatic β-cells and restores th...