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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T75270 | Genevant CL1 | ||
Genevant CL1 is a lipid that can be used for mRNA lipid nanoparticle (LNP) vaccine delivery [1] . | |||
T2080 | LCL161 | IAP | |
LCL161, a SMAC mimetic, effectivity binds to and inhibits multiple IAPs (i.e. XIAP, c-IAP). | |||
T16030 | Mcl1-IN-8 | Others | |
Mcl1-IN-8 is an Mcl-1-PUMA interface inhibitor (Ki: 0.3 μM). In cancer cells, Mcl1-IN-8 shows dual activity on reducing PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis. | |||
T11977 | Mcl1-IN-9 | BCL | |
Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM. | |||
T16029 | Mcl1-IN-3 | Others | |
Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively. | |||
T16027 | Mcl1-IN-1 | Others | |
Mcl1-IN-1 is a myeloid cell factor 1 inhibitor (IC50=2.4 µM). | |||
T11974 | Mcl1-IN-12 | BCL | |
Mcl1-IN-12 has anti-tumor activity.It is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively. | |||
T11973 | Mcl1-IN-11 | BCL | |
Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively. | |||
T24436 | Mcl1-IN-26 | ||
Mcl1-IN-26 is an effective and selective myeloid cell leukemia 1 inhibitor. | |||
T11975 | PROTAC Mcl1 degrader-1 | BCL , PROTACs | |
PROTAC Mcl1 degrader-1 induces the ubiquitination and proteasomal degradation of Mcl-1 by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1 inhibitor S1-6 with μM-range affinity. PROTAC Mcl1 ... | |||
T11976 | Mcl1-IN-4 | Others | |
Mcl1-IN-4 is an inhibitor of Mcl1 ( IC50:0.2 μM). | |||
T39440 | CXCL12 ligand 1 | ||
CXCL12 ligand 1 is the first ligand of the sY12-binding pocket on chemokine CXCL12 . | |||
T13657 | DMCL1-2 | Others | |
dMCL1-2 is a potent and selective myeloid leukemia 1 (MCL1) degrading agent based on PROTAC, which binds to MCL1 with a KD of 30 nM. dmcl-2 activates the apoptosis mechanism by degrading MCL1. | |||
T7082 | HDAC8-IN-1 | HDAC | |
MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5). HDAC8-IN-1 exhibits ... | |||
T83853 | L-K6L9 TFA | ||
L-K6L9, a cytolytic peptide comprised of L-isomer leucine and lysine, demonstrates cytotoxicity against both androgen-independent (LNCaP-CL1) and androgen-dependent (22Rv1 and LNCaP) human prostate cancer cells, with LC5... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04752 | DCLK1 Protein, Human, Recombinant | Human | Baculovirus Insect Cells |
DCLK1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 78.5 kDa and the accession number is O15075-1. | |||
TMPY-04404 | DCLK1 Protein, Human, Recombinant (aa 1-705, His & GST) | Human | Baculovirus Insect Cells |
DCLK1 Protein, Human, Recombinant (aa 1-705, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 106 kDa and the accession number is O15075-1. | |||
TMPY-05337 | CXCL16 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CXCL16 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.5 kDa and the accession number is Q9H2A7. | |||
TMPY-03274 | CXCL11 Protein, Human, Recombinant | Human | E. coli |
I-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low e... | |||
TMPY-02970 | CXCL10 Protein, Human, Recombinant | Human | E. coli |
CXCL10 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.8 kDa and the accession number is P02778. | |||
TMPK-00735 | CXCL13/BCA-1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve li... | |||
TMPY-00566 | CCL18 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its... | |||
TMPK-01269 | CXCL10 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | E. coli |
C-X-C motif ligand 10 (CXCL10), or interferon-inducible protein-10, is a small chemokine belonging to the CXC chemokine family. Its members are responsible for leukocyte trafficking and act on tissue cells, like endothel... | |||
TMPY-02755 | Lymphotactin/XCL1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | Baculovirus Insect Cells |
Lymphotactin/XCL1 Protein, Cynomolgus, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 11.6 kDa. | |||
TMPJ-00673 | CX3CL1/Fractalkine Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Fractalkine(CX3CL1) is a single-pass type I membrane protein and belongs to the intercrine delta family. It consists of an extracellular NH2-terminal domain, a mucin-like stalk, a transmembrane α helix, and a short cytop... | |||
TMPH-01397 | LANCL1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during norma... | |||
TMPY-00433 | CXCL1 Protein, Mouse, Recombinant | Mouse | E. coli |
CXCL1 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.3 kDa and the accession number is A2RTH0. | |||
TMPK-00018 | CXCL13/BCA-1 Protein, Human, Recombinant (His & Sumo) | Human | E. coli |
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve li... | |||
TMPJ-00974 | XCL1 Protein, Human, Recombinant (hFc & His) | Human | HEK293 Cells |
Lymphotactin is a secreted protein which belongs to the intercrine gamma family. It is also a member of the XC chemokine family. XCL1 is found in spleen with highest level, lower in peripheral leukocytes and very low lev... | |||
TMPY-00008 | CXCL1 Protein, Rat, Recombinant | Rat | E. coli |
CXCL1 Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.9 kDa and the accession number is P14095. | |||
TMPY-00573 | MUCL1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
MUCL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 8.4 kDa and the accession number is Q96DR8. | |||
TMPJ-01394 | CXCL15 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Mouse C-X-C motif chemokine 15, also known as Cxcl15, is a secreted protein which is member of the ELR motif-containing CXC chemokines. It expressed at low levels in fetal lung, the expression restricted to the lung, pro... | |||
TMPK-00734 | CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve li... | |||
TMPY-03025 | CXCL16 Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
CXCL16 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46 kDa and the accession number is A0A6M4C4P9. | |||
TMPY-02610 | Lymphotactin/XCL1 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
Lymphotactin/XCL1 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 11.5 kDa and the accession number is P47993. | |||
TMPY-02468 | CCL14 Protein, Human, Recombinant (aa 28-93, His) | Human | E. coli |
CCL14 Protein, Human, Recombinant (aa 28-93, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 9.3 kDa and the accession number is Q16627-1. | |||
TMPY-02180 | CXCL1 Protein, Human, Recombinant (His & NusA) | Human | E. coli |
CXCL1 Protein, Human, Recombinant (His & NusA) is expressed in E. coli expression system with His and NusA tag. The predicted molecular weight is 65 kDa and the accession number is P09341-1. | |||
TMPJ-01001 | CCL11 Protein, Human, Recombinant | Human | E. coli |
C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of all... | |||
TMPY-02026 | CXCL1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
CXCL1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with His and SUMO tag. The predicted molecular weight is 21.3 kDa and the accession number is P09341-1. | |||
TMPY-03905 | Lymphotactin/XCL1 Protein, Canine, Recombinant (His) | Canine | Baculovirus Insect Cells |
Lymphotactin/XCL1 Protein, Canine, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 11.34 kDa and the accession number is A0A8C0PT44. | |||
TMPH-01099 | CLTCL1 Protein, Human, Recombinant (His) | Human | E. coli |
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. CLTCL1 Prot... | |||
TMPJ-00008 | CXCL10 Protein, Human, Recombinant (hFc & His) | Human | HEK293 Cells |
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CX... | |||
TMPY-00090 | SPARCL1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
SPARC-like protein 1 (SPARCL1; also known as SC1, high endothelial venule protein, or hevin) is an extracellular matrix-associated, secreted glycoprotein belonging to the secreted protein acidic and rich in cysteine (SPA... | |||
TMPJ-00952 | CXCL12 Protein, Mouse, Recombinant | Mouse | E. coli |
Mouse Cxcl12 is a secreted and highly conserved protein which belongs to the intercrine alpha (chemokine CxC) family.CXCL12 is widely expressed in various organs including brain, kidney, skeletal muscle, heart, liver, an... | |||
TMPY-02868 | CXCL1 Protein, Human, Recombinant | Human | E. coli |
CXCL1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.9 kDa and the accession number is P09341-1. | |||
TMPK-00721 | CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | HEK293 Cells |
Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its increased levels in tumors improve the prognosis for cancer... | |||
TMPY-03896 | CXCL16 Protein, Canine, Recombinant (hFc) | Canine | HEK293 Cells |
CXCL16 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.1 kDa and the accession number is XP_849304.2. | |||
TMPK-00138 | CXCL16 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
CXC chemokine ligand 16 (CXCL16) is a CXC soluble chemokine, an adhesion molecule and a cell surface scavenger receptor. CXCL16 regulates inflammation, tissue injury and fibrosis. Parenchymal renal cells, vascular wall c... | |||
TMPY-02687 | Lymphotactin/XCL1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Lymphotactin/XCL1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 11.6 kDa and the accession number is P47992. | |||
TMPY-02550 | Eotaxin/CCL11 Protein, Human, Recombinant (His) | Human | E. coli |
CCL11 or chemokine (C-C motif) ligand 11 is a member of the chemokine (C-C motif) ligand family. Chemokin (C-C motif) ligand 11 is a member of the chemokine family. There are four members of the chemokine family: C-C kem... | |||
TMPY-02754 | CXCL16 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
CXCL16 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is Q6AXU5. | |||
TMPK-00017 | CXCL13/BCA-1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve li... | |||
TMPJ-00018 | CCL16 Protein, Human, Recombinant | Human | E. coli |
CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC c... | |||
TMPY-04943 | CXCL10 Protein, Rat, Recombinant (His) | Rat | P. pastoris (Yeast) |
CXCL10 Protein, Rat, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 10 kDa and the accession number is P48973. | |||
TMPY-04984 | CXCL17 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Chemokine (C-X-C motif) ligand 17 (CXCL17) is the latest member of the chemokine family. CXCL17 is a potential oncogene and promising therapeutic target, is an independent biomarker of poor prognosis in patients with bre... | |||
TMPY-05618 | CXCL14 Protein, Human, Recombinant, Biotinylated | Human | E. coli |
CXCL14 Protein, Human, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 9.4 kDa and the accession number is O95715. | |||
TMPH-01984 | CLECL1P Protein, Human, Recombinant (His & Myc) | Human | Baculovirus Insect Cells |
May function in mediating immune cell-cell interactions. May act as a T-cell costimulatory molecule, enhancing anti-CD3-induced proliferation. May play a role in the interaction of dendritic cells with T-cells and the ce... | |||
TMPY-00001 | CXCL14 Protein, Mouse, Recombinant | Mouse | E. coli |
CXCL14 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9.4 kDa and the accession number is Q9WUQ5. | |||
TMPK-00469 | CXCL16 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CXC chemokine ligand 16 (CXCL16) is a CXC soluble chemokine, an adhesion molecule and a cell surface scavenger receptor. CXCL16 regulates inflammation, tissue injury and fibrosis. Parenchymal renal cells, vascular wall c... | |||
TMPH-00485 | CCL17 Protein, Canine, Recombinant (His & KSI) | Canine | E. coli |
CCL17 Protein, Canine, Recombinant (His & KSI) is expressed in E. coli. | |||
TMPY-03781 | CXCL14 Protein, Human, Recombinant | Human | E. coli |
CXCL14 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9.4 kDa and the accession number is O95715. | |||
TMPY-00641 | LEC/CCL16 Protein, Human, Recombinant (His) | Human | E. coli |
CCL16, a chemokine poorly characterized at the functional level. Human CCL16 is a member of the CC family, and its gene maps to human chromosome 17q. In the mouse, only a pseudogene has been identified to date. CCL16 is ... | |||
TMPH-01001 | BCL10 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Plays a key role in both adaptive and innate immune signaling by bridging CARD domain-containing proteins to immune activation. Acts by channeling adaptive and innate immune signaling downstream of CARD domain-containing... | |||
TMPY-05330 | CCL19/MIP-3b Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
CCL19/MIP-3b Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 10.7 kDa and the accession number is O70460. | |||
TMPH-00879 | ASCL1 Protein, Human, Recombinant (His) | Human | E. coli |
ASCL1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.6 kDa and the accession number is P50553. | |||
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