Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mcl1-IN-8 is an Mcl-1-PUMA interface inhibitor (Ki: 0.3 μM). In cancer cells, Mcl1-IN-8 shows dual activity on reducing PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 53.00 | |
1 mL * 10 mM (in DMSO) | 5 days | $ 130.00 |
Description | Mcl1-IN-8 is an Mcl-1-PUMA interface inhibitor (Ki: 0.3 μM). In cancer cells, Mcl1-IN-8 shows dual activity on reducing PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis. |
Targets&IC50 | MCL1:0.3 μM (ki) |
Molecular Weight | 393.5 |
Formula | C22H23N3O2S |
CAS No. | 678158-55-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (127.06 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Mcl1-IN-8 678158-55-9 Others Mcl-1-IN-8 Mcl1IN8 Mcl1 IN 8 inhibitor inhibit