chf — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T68042	CHF-4227	Chf4227,Chf 4227	Estrogen Receptor/ERR
	CHF-4227 is a novel, potent and selective estrogen receptor modulator that reduces cholesterol and LDL cholesterol concentrations.		Estrogen Receptor/ERR
T38625	Tanimilast	CHF-6001	PDE
	Tanimilast (CHF-6001) is a novel, potent and selective phosphodiesterase 4 inhibitor with an IC 50 value of 0.026 ± 0.006 nM.Tanimilast has potent anti-inflammatory activity and is indicated for topical use in the lungs....		PDE
T30875	CHF 1255	CHF1255,CHF-1255
	CHF 1255 is a potential drug for the treatment of heart failure.
T33711L	Nolomirole HCl	CHF 1035 HCl,CHF 1035,CHF1035,CHF1035 HCl,CHF-1035 HCl,CHF-1035,Nolomirole Hydrochloride	Dopamine Receptor , Norepinephrine
	Nolomirole HCl (CHF 1035) is a novel selective dopamine agonist with oral activity and inhibitory effects on norepinephrine release, which can be used to study mild chronic heart failure.		Dopamine Receptor , Norepinephrine
T30876	CHF 2819	Ganstigmine HCl,CHF-2819,Ganstigmine hydrochloride,CHF2819
	CHF 2819 is a pure AR antagonist with AR nuclear translocation inhibition activity. It suppresses castration and prevents the growth of prostate cancer cells.
T30878	CHF-2993	CHF 2993,5NY5Q1OUZ3,UNII-5NY5Q1OUZ3,CHF2993
	CHF-2993 is a bio-active chemical.
T70572	CHF-2060
	CHF-2060 is a novel acetylcholinesterase inhibitor.
T30879	CHF-5022	UNII-JO8EVV007Q,CHEMBL196246,CHF5022
	CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).
T30877	CHF-1024	UNII-HPH2L3QA2F
	CH-5137291 is a pure AR antagonist with AR nuclear translocation inhibition activity. It inhibits castration and prevents the growth of prostate cancer cells.
T27606	Indantadol HCl	CHF-3381,CMP-3381,GT-3381,V-3381,CNP-3381,Indantadol	MAO , NMDAR
	Indantadol HCl (CHF-3381) is a NMDA antagonist and nonselective MAO inhibitor.		MAO , NMDAR
T13992	CHF5407	SVT-47060	AChR
	CHF5407（SVT-47060） is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect on bronchospasm and may be used in the study of respiratory disorders.CHF...		AChR
T70376	CHF-6366
	CHF-6366 is a dual-action chemical compound acting as a potent M3 muscarinic antagonist and β2-adrenergic receptors agonist, with respective pK i values of 10.4 and 11.4. Additionally, it exhibits weak calcium channel in...
T33711	Nolomirole	CHF1025,CHF-1025,CHF 1025
	Nolomirole is a dopamine receptor agonist that reduces symptoms of congestive heart failure caused by monoclinine.
T2262	Itanapraced	CHF5074,CSP-1103	Beta Amyloid , Gamma-secretase
	Itanapraced (CHF5074), a γ-secretase modulator, reduces Aβ42/40 secretion (IC50: 3.6/18.4 μM).		Beta Amyloid , Gamma-secretase
T70375	ZEN-2759		Epigenetic Reader Domain
	ZEN-2759 is a potent BET small molecule inhibitor of BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2).		Epigenetic Reader Domain
T69233	Ganstigmine
	Ganstigmine is an acetylcholinesterase inhibitor for Alzheimer's disease.
T70638	P38-α MAPK-IN-5
	P38-α MAPK-IN-5 is a potent inhibitor of p38α, demonstrating inhibitory concentrations (IC50) of 0.1 nM for p38α, 0.2 nM for p38β, 944 nM for p38γ, and 4100 nM for p38δ. It exhibits anti-inflammatory properties and holds...
T1461	Candesartan	CV 11974	RAAS
	Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.		RAAS
T5329	Trandolapril		Angiotensin-converting Enzyme (ACE)
	Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat.		Angiotensin-converting Enzyme (ACE)
T71944	FGF/PDGF/VEGF RTK Inhibitor
	FGF/PDGF/VEGF RTK Inhibitor is a potent, reversible, atp-competitive inhibitor against pdgfrβ, fgfr-1, and vegfr-2 (ic50 = 20, 90, and 240 nm, respectively) and effectively suppresses vegf-stimulated proliferation of h...