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Indantadol HCl

Catalog No. T27606 CAS 202914-18-9

Synonyms: CHF-3381, CMP-3381, GT-3381, V-3381, CNP-3381, Indantadol

Indantadol HCl (CHF-3381) is a NMDA antagonist and nonselective MAO inhibitor.

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Indantadol HCl, CAS 202914-18-9

Pack Size	Availability	Price/USD
1 mg	In stock	$ 195.00
5 mg	In stock	$ 430.00
10 mg	In stock	$ 636.00
25 mg	In stock	$ 987.00
50 mg	In stock	$ 1,360.00
100 mg	In stock	$ 1,830.00
500 mg	In stock	$ 3,680.00

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Purity: 98.24%

Biological Description

Chemical Properties

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Description

Indantadol HCl (CHF-3381) is a NMDA antagonist and nonselective MAO inhibitor.

In vivo

In a human heat-capsaicin-induced pain model, Indantadol HCl at a dose of 500 mg effectively reduced the area of secondary hyperalgesia to 67%. Indantadol HCl undergoes extensive liver metabolism, withthe formation of two major metabolites - CHF-3567 and 2-aminoindane. The drug is excreted in urine partially as the parent compound, but mostly as CHF-3567. The tolerability profile of Indantadol HCl at single doses up to 600 mg and twice-daily doses up to 400 mg in clinical trials was significantly more favorable than for other NMDA antagonists. Most side effects have been observed to be mild, and include dizziness and asthenia. Indantadol HCl is currently in phase II clinical trials in patients with diabetic peripheral neuropathic pain.[1]

Synonyms	CHF-3381, CMP-3381, GT-3381, V-3381, CNP-3381, Indantadol
Molecular Weight	226.7
Formula	C11H15ClN2O
CAS No.	202914-18-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Mattia C, et al. Indantadol, a novel NMDA antagonist and nonselective MAO inhibitor for the potential treatment of neuropathic pain. IDrugs. 2007;10(9):636-644.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Neurodegenerative Disease Compound Library Drug Repurposing Compound Library Inhibitor Library Bioactive Compounds Library Max Clinical Compound Library Bioactive Compound Library

Related Products

Related compounds with same targets

Isogentisin MAO-IN-1 MAO-B-IN-17 5-Hydroxy-1-methoxyxanthone Bifemelane hydrochloride Echitovenidine Minaprine 4-Hydroxyderricin

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Indantadol HCl 202914-18-9 Metabolism Neuroscience MAO NMDAR CNP3381 CHF 3381 GT3381 CMP3381 CHF-3381 V3381 CMP 3381 CMP-3381 CNP 3381 GT-3381 GT 3381 CHF3381 V-3381 CNP-3381 V 3381 Indantadol inhibitor inhibit

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