Search Result

Search Results for " b-23 "

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
TP1162	Fibrinopeptide B, human TFA (36204-23-6 free base)	FPB,human TFA,Fibrinopeptide B, human TFA
	FibrinopeptideB,human is a 14-amino acid polypeptide released from the amino terminus of the fibrinogen segment.
T78859	MAO-B-IN-23		Monoamine Oxidase
	MAO-B-IN-23, also known as Compound 11f, is a reversible and competitive monoamine oxidase B (MAO-B) inhibitor with an IC50 value of 1.44 μM and a Ki of 0.51 μM [1].		Monoamine Oxidase
T5612	Sudan III	Solvent Red 23,Tetrazobenzene-β-naphthol,111440 Red,Sudan Red III	Others
	Sudan III (Solvent Red 23) is a solvent dye used to color nonpolar substances.		Others
TP1126	InsB 9-23	Insulin B chain (9-23)
	InsB (9-23) is an insulin B-chain peptide that binds to a class II histocompatibility complex (MHC) allele called I-Ag7.
T83547	(Des-Bromo)-Neuropeptide B (1-23) (human)
	'(Des-Bromo)-Neuropeptide B (1-23) (human)' is an agonist for orphan G-protein-coupled receptors, exhibiting a K i of 1.2 nM for GPR7 (NPBW1) and 341 nM for GPR8 (NPBW2) respectively [1].
T40132	Insulin β Chain Peptide (15-23)
	Insulin β Chain Peptide (15-23), also referred to as INS, is an insulin-derived peptide that is specifically recognized by islet-associated T cells. The tetramer of Insulin β Chain Peptide (15-23) effectively stained the...
T65421	Rifamycin O
	Rifamycin O is a useful organic compound for research related to life sciences. The catalog number is T65421 and the CAS number is 14487-05-9.
T14363	AZ-23	AZ 23,AZ23	Trk receptor
	AZ-23 is an inhibitor of ATP-competitive and Trk kinase A/B/C. For TrkA, TrkB, FGFR1, Flt3, Ret, MuSk, Lck, the IC50s values are 2 nM, 8 nM, 24 nM, 52 nM, 55 nM, 84 nM, 99 nM, respectively.		Trk receptor
T6039	TAK-285	TAK285,TAK 285	EGFR , MEK , HER , Aurora Kinase
	TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1.		EGFR , MEK , HER , Aurora Kinase
T14367	AZ1495		IRAK , CDK , Haspin Kinase
	AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffu...		IRAK , CDK , Haspin Kinase
T10215	AAPK-25		Apoptosis , PLK , Aurora Kinase
	AAPK-25 is a potent and selective Aurora/PLK dual inhibitor with anti-tumor activity, which can cause mitotic delay and arrest cells in prometaphase, followed by a surge in apoptosis. AAPK-25 targets Aurora-A/-B/-C with ...		Apoptosis , PLK , Aurora Kinase
T22702	CYM 50769		Neuropeptide W
	CYM 50769 is a neuropeptide W/B receptor 1 (NPBWR1, GPR7) antagonist(IC50 = 0.12 μM). CYM 50769 inhibited NPW activation of NPBWR1 with a submicromolar IC50, and displayed high selectivity against a broad array of off-ta...		Neuropeptide W
T2247	KenPaullone	9-Bromopaullone,NSC-664704	GSK-3 , CDK
	KenPaullone (9-Bromopaullone), a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell differentiation. Kenpaullone promotes iTreg cell differentiation through increased and prolonged transcription of foxp...		GSK-3 , CDK
T3579	PLX8394		Raf
	PLX8394 is an orally active inhibitor of serine/threonine-protein kinase B-Raf (BRAF) protein. PLX8394 can selectively bind to and inhibit the activity of both wild-type and mutated forms of BRAF, then inhibit the prolif...		Raf
T35610	2,5-dimethyl Celecoxib		Apoptosis , Wnt/beta-catenin , Prostaglandin Receptor
	2,5-dimethyl Celecoxib is a derivative of celecoxib that does not inhibit COX-2 (IC50 = >100 μM).1 It does inhibit microsomal prostaglandin E synthase-1 (mPGES-1) in HeLa cells (IC50 = 15.6 μM) and reduces prostaglandin ...		Apoptosis , Wnt/beta-catenin , Prostaglandin Receptor
T22272	Lifirafenib	BGB-283,Beigene-283	EGFR , Raf
	Lifirafenib (Beigene-283) is a potent inhibitor of RAF family kinases and EGFR in biochemical assays with IC50 of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant respective...		EGFR , Raf
T124685	Myrtucommulone B
	Myrtucommulone B is a useful organic compound for research related to life sciences. The catalog number is T124685 and the CAS number is 54247-23-3.
T80290	PP102
	PP102, an antimicrobial peptide, exhibits activity against gram-positive bacteria, including B. subtilis (MIC: 25 µM), S. aureus (MIC: 13.3 µM), S. lutea (MIC: 63 µM), and B. pumilus (MIC: 23 µM) [1].
T124486	Swietenocoumarin B
	Swietenocoumarin B is a useful organic compound for research related to life sciences. The catalog number is T124486 and the CAS number is 64652-23-9.
T61603	H3R antagonist 2
	H3R antagonist 2 (Compound 23) is a multitarget histamine H3 receptor antagonist. It exhibits inhibitory effects on acetylcholinesterase, butyrylcholinesterase, and human monoamine oxidase B (hMAO B) with IC50 values of ...
T68485	Apilimod HCl
	Apilimod dimesylate is a potent and selective PIKfyve inhibitor. It exhibits no significant activity at other lipid kinases and protein kinases, including PIP4K, PIP5K, mTOR, PI3K and PI4K. Apilimod dimesylate inhibits c...
T37719	Galbinic Acid
	Galbinic acid is a depsidone lichen metabolite that has been found in U. undulata.1,2 It is active against the Gram-positive bacteria B. cereus, B. subtilis, and S. aureus, but not S. epidermidis (MICs = 62.5, 62.5, 250,...
T36460	CAY10736	CAY10736
	CAY10736 is an anticancer compound.1 It inhibits proliferation in a panel of melanoma and breast, pancreatic, and lung cancer cell lines (IC50s = 0.827-9.89 μM). CAY10736 inhibits migration and epithelial-to-mesenchymal ...
T36497	CAY10735	CAY10735
	CAY10735 is an anticancer compound.1 It inhibits proliferation in a panel of melanoma and breast, pancreatic, and lung cancer cell lines (IC50s = 0.674-11.56 μM). CAY10735 inhibits migration of and the epithelial-to-mese...
T38002	LEO 39652
	LEO 39652, a dual-soft PDE4 inhibitor, demonstrates potent inhibition of PDE4 subtypes A, B, C, and D with respective IC50 values of 1.2 nM, 1.2 nM, 3.0 nM, and 3.8 nM. Additionally, it inhibits TNF-α with an IC50 of 6.0...
T36197	CAY10747
	CAY10747 is an inhibitor of the protein-protein interaction between heat shock protein 90 (Hsp90) and cell division cycle 37 (Cdc37) and a derivative of celastrol .1It decreases protein levels of the Hsp90-Cdc37 complex ...
T36779	NG 25 (hydrochloride hydrate)
	NG 25 is a type II kinase inhibitor that inhibits MAP4K2 and TAK1 (IC50s = 21.7 and 149 nM, respectively).1It also inhibits the Src family kinases Src and LYN (IC50s = 113 and 12.9 nM, respectively) and Abl family kinase...

Compounds

Fibrinopeptide B, human TFA (36204-23-6 free base)

TP1162

Synonym: FPB,human TFA,Fibrinopeptide B, human TFA

Target: Monoamine Oxidase

Sudan III

T5612

Synonym: Solvent Red 23,Tetrazobenzene-β-naphthol,111440 Red,Sudan Red III

Target: Others

InsB 9-23

TP1126

Synonym: Insulin B chain (9-23)

Target:

(Des-Bromo)-Neuropeptide B (1-23) (human)

T83547

Synonym:

Target:

Insulin β Chain Peptide (15-23)

Synonym: TAK285,TAK 285

Target: EGFR, MEK, HER, Aurora Kinase

AZ1495

T14367

Synonym:

Target: IRAK, CDK, Haspin Kinase

AAPK-25

T10215

Synonym:

Target: Apoptosis, PLK, Aurora Kinase

CYM 50769

T22702

Synonym:

Target: Neuropeptide W

KenPaullone

T2247

Synonym: 9-Bromopaullone,NSC-664704

2,5-dimethyl Celecoxib

T35610

Synonym:

Target: Apoptosis, Wnt/beta-catenin, Prostaglandin Receptor

Lifirafenib

T22272

Synonym: BGB-283,Beigene-283

NG 25 (hydrochloride hydrate)

T36779

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
T6S2246	Alisol B 23-acetate	Alisol B Acetate,Alisol B monoacetate,23-O-Acetylalisol B,23-Acetylalismol B	Others
	1. Alisol B 23-acetate (Alisol B Acetate) produces protective effect against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes. 2. Alisol B 23-acetate produces promotiv...		Others
T83443	16β-Hydroperoxyalisol B 23-acetate
	16β-Hydroperoxyalisol B 23-acetate, a natural product, is isolable from Alisma orientale [1].
TN2117	Pulsatilloside E	Pulchinenoside E	Others
	Pulsatilloside E (Pulchinenoside E) is a natural product isolated from the roots of Pulsatilla chinensis (Ranunculaceae).		Others
T37609	(rel)-Asperparaline A
	Aspergillimide is a fungal metabolite originally isolated from A. japonicus.1 It reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) la...

Natural Products

Alisol B 23-acetate

T6S2246

Synonym: Alisol B Acetate,Alisol B monoacetate,23-O-Acetylalisol B,23-Acetylalismol B

Target: Others

16β-Hydroperoxyalisol B 23-acetate

Synonym: Pulchinenoside E

Target: Others

(rel)-Asperparaline A

T37609

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-00737	PDYN Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Proenkephalin-B(PDYN), belongs to the opioid neuropeptide precursor family. The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing. Leu-enkephalins, which is a ...
TMPY-04259	Nucleophosmin Protein, Human, Recombinant (aa 2-294, His)	Human	E. coli
	Nucleophosmin Protein, Human, Recombinant (aa 2-294, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34 kDa and the accession number is P06748-1.
TMPY-01925	Nucleophosmin Protein, Human, Recombinant (His)	Human	E. coli
	Nucleophosmin Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 17.8 kDa and the accession number is P06748-1.
TMPY-00168	MPIF-1/CCL23 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	MPIF-1/CCL23 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.9 kDa and the accession number is P55773.3.
TMPY-03886	MPIF-1/CCL23 Protein, Human, Recombinant	Human	E. coli
	MPIF-1/CCL23 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11.4 kDa and the accession number is P55773-1.
TMPH-02342	Collagenase Protein, Hypoderma lineatum, Recombinant (His & Myc)	Hypoderma lineatum	E. coli
	This enzyme is a serine protease capable of degrading the native triple helix of collagen. Also cleaves the B chain of insulin at the 15-Leu-\|-Try-16 and 22-Arg-\|-Gly-23 bonds. Hydrolyzes casein, but not Px-Pro-Leu-Gly-P...
TMPJ-00066	BCMA/TNFRSF17 Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
	B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. Mouse BCMA is a 185 amino acid (aa) protein consisting of a 49 aa extracellular domain, a 23 aa transmembrane...
TMPK-01416	HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	HLA-B15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B15:01 we...
TMPK-01413	H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi)	Mouse	HEK293 Cells
	Ovalbumin (OVA) has been historically a popular source of such antigens, since OVA can induce both humoral and cellular immune responses based on well-characterised peptide epitopes. The OVA257-264 octapeptide was one of...
TMPK-01412	HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	HLA-B15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B15:01 we...