Home Tools
Log in
Cart

Search Result

Search Results for " alzheimer's "

20

Compounds

Cat No. Product Name Synonyms Targets
T20993 Memantine Others
Memantine, an amantadine derivative with some dopaminergic effects, has been proposed as an antiparkinson agent and has may be used to treat moderate to severe Alzheimer's disease. It acts on the glutamatergic system by ...
T9062 CA77.1 Autophagy
CA77.1(CA) is a novel chaperon-mediated autophagy (CMA) activator for the treatment of Alzheimer's disease (AD).
T21883 Gedunin HSP
Gedunin is an important limonoid present in several genera of the Meliaceae family, mainly in seeds. Gedunin is an Hsp90 inhibitor, and inhibits ovarian cancer cell proliferation.
TN1772 Isoastilbin Anti-infection , Tyrosinase , Antibacterial
Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL, Isoastilbin has anti-acne an...
T9989 AChE-IN-27 Others
AChE-IN-27 is a small molecule used for high-throughput assays.
TN6919 Methyl tridecanoate Beta Amyloid , AChE
Methyl tridecanoate is a natural product.
T2S1720 Huperzine B AChE
1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Alzheimer's disease therapy.
T3S1873 Talatisamine Potassium Channel
1. Talatisamine (12 μM) and TEA (5mM) inhibits the enhanced I(K) caused by Aβ4 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response. 2. Talat...
T3S0195 Nootkatone AMPK
1. Nootkatone can provide effective tick control. 2. (+)-Nootkatone has antiallergic, anti-inflammatory, and antiplatelet activities. 3. Nootkatone can prevent obesity and improve physical performance through AMPK activa...
T7837 SR8278 Others
SR8278 is an REV-ERBα antagonist(EC50 = 0.47 µM), blocking activation of the receptor by the synthetic agonist GSK 4112
TN1390 Angeloylgomisin Q Others
Angeloylgomisin Q is a natural product from Schizandra chinensis BAILL.
T11175 Elenbecestat E2609 Beta-Secretase , BACE
Elenbecestat (E2609) is an effective oral bioutilization and CNS penetrating ACE-1 inhibitor for the treatment of Alzheimer's disease.
T6058 LY2886721 Beta-Secretase , BACE
LY2886721, a BACE inhibitor, is used for the therapy of Alzheimer's Disease.
TN1355 Acanthoside B Immunology/Inflammation related
Acanthoside B is a lignan with anti-inflammatory and anti-amnesic effects. Acanthoside B can be used for studies about Alzheimer's disease and lung inflammation.
T1132 Nicergoline Nicergolinum,Nimergoline Adrenergic Receptor
Nicergoline (Nicergolinum) is an ergot derivative used to treat senile dementia and other disorders with vascular origins.
T3394 Timosaponin BII Prototimosaponin A III Beta Amyloid , Others , BACE
Timosaponin BII (Prototimosaponin A III) has anti-dementia activity and may be useful for the treatment of type 2 diabetes. Timosaponin BII has antioxidant activity, can inhibit the up-regulation of BACE1 and reduced the...
T8230 PNU112455A hydrochloride PNU 112455A CDK
PNU112455A hydrochloride is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.
T21439 Tacrine CS 12602,Tacrinum,Tetrahydroaminocrine AChR
Tacrine (CS 12602) is an indirect cholinergic agonist and centrally acting anticholinesterase. It is approved for the treatment of Alzheimer's disease.
T23348 SEN12333 SEN 12333 AChR
SEN12333 is an α7 nicotinic acetylcholine receptor (nAChR) agonist
T0130 Physostigmine Salicylate AChR , AChE
Physostigmine, a parasympathomimetic alkaloid, is a reversible cholinesterase inhibitor. It extracts from the Calabar bean.
1 2 3 4 5 ... 28
TargetMol