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Search Results for " axin "

20

Compounds

Cat No. Product Name Synonyms Targets
T22884 JW 67 Wnt/beta-catenin
JW 67 is an inhibitor of canonical Wnt pathway signaling. JW 67 rapidly reduced active β-catenin with a subsequent downregulation of Wnt target genes, including AXIN2, SP5, and NKD1.
T1580 Desvenlafaxine WY 45233 Succinate,O-Desmethylvenlafaxine 5-HT Receptor , Serotonin Transporter , Norepinephrine
Desvenlafaxine (O-Desmethylvenlafaxine) is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) and is used as an antidepressive age...
T3783 Fraxin Fraxoside,Fraxetin-8-O-glucoside,Paviin OAT , transporter , PDE
Fraxin (Fraxoside) is a glucoside of fraxetin.
T9358 N,N,O-Tridesmethylvenlafaxine Tridesmethylvenlafaxine Others , Endogenous Metabolite
N,N,O-Tridesmethylvenlafaxine (Tridesmethylvenlafaxine) is a huamn endogenous metabolite.
T5380 Ansofaxine hydrochloride LPM570065,LY03005 Dopamine Receptor , 5-HT Receptor , Norepinephrine
Ansofaxine hydrochloride (LY03005) is a serotonin-norepinephrine-dopamine reuptake inhibitor (IC50s: 723, 763 and 491 nM, respectively).
T2064 Semaxinib SU5416 VEGFR
Semaxinib (SU5416) is a potent and selective VEGFR2 inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR than PDGFRβ, lack of activity against InsR, EGFR, and FGFR. Semaxanib reversibly inhibits ATP binding to the...
T6S0071 Fraxinellone HIF/HIF Prolyl-Hydroxylase , STAT , PD-1/PD-L1
1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhibited a variety of insecticidal activities including feeding...
T0472 Venlafaxine hydrochloride Venlafaxine HCl,Wy 45030 hydrochloride 5-HT Receptor , Serotonin Transporter
Venlafaxine hydrochloride (Wy 45030 hydrochloride) is a cyclohexanol and phenylethylamine derivative that functions as a SEROTONIN AND NORADRENALINE REUPTAKE INHIBITOR (SNRI) and is used as an ANTIDEPRESSIVE AGENT.
T2496 (Z)-Semaxinib SU5416 VEGFR
(Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR over PDGFRβ, no inhibition for FGFR, InsR, and EGFR. (Z)-Semaxinib is a quinolone derivative w...
T22453 Venlafaxine Wy 45030 Serotonin Transporter
Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disorder (MDD), panic disorder and social phobia.
T3366 Cephalotaxine ZINC19795976,(-)-Cephalotaxine,Cephalotaxlen Antiviral , Influenza Virus
Cephalotaxine (ZINC19795976) is an antiviral and an antitumor agent.
T3818 Fraxinol Others , P450
Fraxinol is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 5, 7-dimethoxy-2h-chromen-2-one. It is generated by cyp1a2, cyp2a6, cyp2b6, cyp2c9, cyp2c19, and cyp2e1 enzymes via an...
T10415 Autotaxin-IN-3 PDE
Autotaxin-IN-3 is an inhibitor of Autotaxin (IC50 = 2.4 nM) which is responsible for the increase in lysophosphatidic acid in ascites and plasma.
T6188 Desvenlafaxine succinate hydrate O-Desmethylvenlafaxine succinate hydrate,WY 45233 Succinate,Desvenlafaxine Succinate 5-HT Receptor , Serotonin Transporter , Norepinephrine
Desvenlafaxine succinate hydrate (WY 45233 Succinate) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).
TP2068L Cyclotraxin B acetate(1203586-72-4 free base) Trk receptor
Cyclotraxin B acetate is an antagonist of TrkB receptors; inhibits BDNF-induced TrkB activity (IC50 = 0.30 nM). Allosterically alters TrkB receptor conformation but does not alter BDNF binding. Prevents BDNF-induced cold...
T73977 (S)-Dehydro Venlafaxine
(S)-Dehydro Venlafaxine is an inactive S-enantiomer of Dehydro Venlafaxine. Dehydro Venlafaxine is an impurity of Venlafaxine hydrochloride. Venlafaxine hydrochloride (Wy 45030 hydrochloride) is a potent serotonin (5-HT)...
T41060 Ansofaxine Ansofaxine,LPM570065freebase,Toludesvenlafaxine,LY03005freebase
Ansofaxine, an SNRI compound, is commonly utilized in depression research as a serotonin-norepinephrine reuptake inhibitor.
TN6236 Taraxinic acid
Taraxinic acid is a natural product for research related to life sciences. The catalog number is TN6236 and the CAS number is 75911-33-0.
TN3787 Decinnamoyltaxinine J Others
Decinnamoyltaxinine J is a natural product from Taxus brevifolia Nutt.
TN5116 Taxinine M Others
Taxinine M is a natural product from Chinese yew Taxus chinensis.

Compounds

JW 67
T22884
Synonym:
Target: Wnt/beta-catenin
Desvenlafaxine
T1580
Synonym: WY 45233 Succinate,O-Desmethylvenlafaxine
Target: 5-HT Receptor, Serotonin Transporter, Norepinephrine
Fraxin
T3783
Synonym: Fraxoside,Fraxetin-8-O-glucoside,Paviin
Target: OAT, transporter, PDE
N,N,O-Tridesmethylvenlafaxine
T9358
Synonym: Tridesmethylvenlafaxine
Target: Others, Endogenous Metabolite
Ansofaxine hydrochloride
T5380
Synonym: LPM570065,LY03005
Target: Dopamine Receptor, 5-HT Receptor, Norepinephrine
Semaxinib
T2064
Synonym: SU5416
Target: VEGFR
Fraxinellone
T6S0071
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase, STAT, PD-1/PD-L1
Venlafaxine hydrochloride
T0472
Synonym: Venlafaxine HCl,Wy 45030 hydrochloride
Target: 5-HT Receptor, Serotonin Transporter
(Z)-Semaxinib
T2496
Synonym: SU5416
Target: VEGFR
Venlafaxine
T22453
Synonym: Wy 45030
Target: Serotonin Transporter
Cephalotaxine
T3366
Synonym: ZINC19795976,(-)-Cephalotaxine,Cephalotaxlen
Target: Antiviral, Influenza Virus
Fraxinol
T3818
Synonym:
Target: Others, P450
Autotaxin-IN-3
T10415
Synonym:
Target: PDE
Desvenlafaxine succinate hydrate
T6188
Synonym: O-Desmethylvenlafaxine succinate hydrate,WY 45233 Succinate,Desvenlafaxine Succinate
Target: 5-HT Receptor, Serotonin Transporter, Norepinephrine
Cyclotraxin B acetate(1203586-72-4 free base)
TP2068L
Synonym:
Target: Trk receptor
(S)-Dehydro Venlafaxine
T73977
Synonym:
Target:
Ansofaxine
T41060
Synonym: Ansofaxine,LPM570065freebase,Toludesvenlafaxine,LY03005freebase
Target:
Taraxinic acid
TN6236
Synonym:
Target:
Decinnamoyltaxinine J
TN3787
Synonym:
Target: Others
Taxinine M
TN5116
Synonym:
Target: Others
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TargetMol