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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22884 | JW 67 | Wnt/beta-catenin | |
JW 67 is an inhibitor of canonical Wnt pathway signaling. JW 67 rapidly reduced active β-catenin with a subsequent downregulation of Wnt target genes, including AXIN2, SP5, and NKD1. | |||
T1580 | Desvenlafaxine | WY 45233 Succinate,O-Desmethylvenlafaxine | 5-HT Receptor , Serotonin Transporter , Norepinephrine |
Desvenlafaxine (O-Desmethylvenlafaxine) is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) and is used as an antidepressive age... | |||
T3783 | Fraxin | Fraxoside,Fraxetin-8-O-glucoside,Paviin | OAT , transporter , PDE |
Fraxin (Fraxoside) is a glucoside of fraxetin. | |||
T9358 | N,N,O-Tridesmethylvenlafaxine | Tridesmethylvenlafaxine | Others , Endogenous Metabolite |
N,N,O-Tridesmethylvenlafaxine (Tridesmethylvenlafaxine) is a huamn endogenous metabolite. | |||
T5380 | Ansofaxine hydrochloride | LPM570065,LY03005 | Dopamine Receptor , 5-HT Receptor , Norepinephrine |
Ansofaxine hydrochloride (LY03005) is a serotonin-norepinephrine-dopamine reuptake inhibitor (IC50s: 723, 763 and 491 nM, respectively). | |||
T2064 | Semaxinib | SU5416 | VEGFR |
Semaxinib (SU5416) is a potent and selective VEGFR2 inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR than PDGFRβ, lack of activity against InsR, EGFR, and FGFR. Semaxanib reversibly inhibits ATP binding to the... | |||
T6S0071 | Fraxinellone | HIF/HIF Prolyl-Hydroxylase , STAT , PD-1/PD-L1 | |
1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhibited a variety of insecticidal activities including feeding... | |||
T0472 | Venlafaxine hydrochloride | Venlafaxine HCl,Wy 45030 hydrochloride | 5-HT Receptor , Serotonin Transporter |
Venlafaxine hydrochloride (Wy 45030 hydrochloride) is a cyclohexanol and phenylethylamine derivative that functions as a SEROTONIN AND NORADRENALINE REUPTAKE INHIBITOR (SNRI) and is used as an ANTIDEPRESSIVE AGENT. | |||
T2496 | (Z)-Semaxinib | SU5416 | VEGFR |
(Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR over PDGFRβ, no inhibition for FGFR, InsR, and EGFR. (Z)-Semaxinib is a quinolone derivative w... | |||
T22453 | Venlafaxine | Wy 45030 | Serotonin Transporter |
Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disorder (MDD), panic disorder and social phobia. | |||
T3366 | Cephalotaxine | ZINC19795976,(-)-Cephalotaxine,Cephalotaxlen | Antiviral , Influenza Virus |
Cephalotaxine (ZINC19795976) is an antiviral and an antitumor agent. | |||
T3818 | Fraxinol | Others , P450 | |
Fraxinol is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 5, 7-dimethoxy-2h-chromen-2-one. It is generated by cyp1a2, cyp2a6, cyp2b6, cyp2c9, cyp2c19, and cyp2e1 enzymes via an... | |||
T10415 | Autotaxin-IN-3 | PDE | |
Autotaxin-IN-3 is an inhibitor of Autotaxin (IC50 = 2.4 nM) which is responsible for the increase in lysophosphatidic acid in ascites and plasma. | |||
T6188 | Desvenlafaxine succinate hydrate | O-Desmethylvenlafaxine succinate hydrate,WY 45233 Succinate,Desvenlafaxine Succinate | 5-HT Receptor , Serotonin Transporter , Norepinephrine |
Desvenlafaxine succinate hydrate (WY 45233 Succinate) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI). | |||
TP2068L | Cyclotraxin B acetate(1203586-72-4 free base) | Trk receptor | |
Cyclotraxin B acetate is an antagonist of TrkB receptors; inhibits BDNF-induced TrkB activity (IC50 = 0.30 nM). Allosterically alters TrkB receptor conformation but does not alter BDNF binding. Prevents BDNF-induced cold... | |||
T73977 | (S)-Dehydro Venlafaxine | ||
(S)-Dehydro Venlafaxine is an inactive S-enantiomer of Dehydro Venlafaxine. Dehydro Venlafaxine is an impurity of Venlafaxine hydrochloride. Venlafaxine hydrochloride (Wy 45030 hydrochloride) is a potent serotonin (5-HT)... | |||
T41060 | Ansofaxine | Ansofaxine,LPM570065freebase,Toludesvenlafaxine,LY03005freebase | |
Ansofaxine, an SNRI compound, is commonly utilized in depression research as a serotonin-norepinephrine reuptake inhibitor. | |||
TN6236 | Taraxinic acid | ||
Taraxinic acid is a natural product for research related to life sciences. The catalog number is TN6236 and the CAS number is 75911-33-0. | |||
TN3787 | Decinnamoyltaxinine J | Others | |
Decinnamoyltaxinine J is a natural product from Taxus brevifolia Nutt. | |||
TN5116 | Taxinine M | Others | |
Taxinine M is a natural product from Chinese yew Taxus chinensis. |