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Desvenlafaxine succinate hydrate

Catalog No. T6188 CAS 386750-22-7

Synonyms: O-Desmethylvenlafaxine succinate hydrate, Desvenlafaxine Succinate, WY 45233 Succinate, WY 45233 Succinate, O-Desmethylvenlafaxine succinate hydrate, Desvenlafaxine Succinate

Desvenlafaxine succinate hydrate is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).

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Desvenlafaxine succinate hydrate, CAS 386750-22-7

Pack Size	Availability	Price/USD
5 mg	In stock	35.00
10 mg	In stock	50.00
25 mg	In stock	88.00
50 mg	In stock	115.00
100 mg	In stock	196.00
500 mg	In stock	774.00
1 mL * 10 mM (in DMSO)	In stock	49.00

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Purity 99.39%

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Description	Desvenlafaxine succinate hydrate is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).
Targets&IC50	5-HT , Norepinephrine (NE)
In vivo	Desvenlafaxine Succinate rapidly penetrates the male rat brain and hypothalamus. Desvenlafaxine Succinate significantly increases extracellular NE levels compared with baseline in the male rat hypothalamus but had no effect on DA levels using microdialysis. [1] Desvenlafaxine Succinate exhibits a linear and dose-proportional pharmacokinetic single-dose profile in a dose range from 100 to 600 mg/day. The absolute bioavailability of the oral formulation is 80.5%.[2]

Synonyms	O-Desmethylvenlafaxine succinate hydrate , Desvenlafaxine Succinate , WY 45233 Succinate , WY 45233 Succinate , O-Desmethylvenlafaxine succinate hydrate , Desvenlafaxine Succinate
Purity	99.39%
Molecular Weight	399.48
Formula	C20H33NO7
CAS No.	386750-22-7

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 6 months

Solubility Information

DMSO: 33 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Solution 1

0.5% methylcellulose/0.2% Tween 80: 30 mg/mL

Citations

References and Literature

1. Deecher DC, et al. J Pharmacol Exp Ther, 2006, 318(2), 657-665. 2. Sopko MA Jr, et al. Ann Pharmacother, 2008, 42(10), 1439-1446.

Related compound libraries

This product is contained In the following compound libraries：

Approved Drug Library Bioactive Compound Library Inhibitor Library Neuronal Signaling Compound Library Endocrinology-Hormone Compound Library Serotonin Receptor-Targeted Compound Library FDA-Approved Drug Library GPCR Compound Library CNS-Penetrant Compound Library Drug Repurposing Compound Library Target-Focused Phenotypic Screening Library Anti-Neurodegenerative Disease Compound Library FDA-Approved & Pharmacopeia Drug Library Anti-Alzheimer's Disease Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

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