keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cyclotraxin B acetate is an antagonist of TrkB receptors; inhibits BDNF-induced TrkB activity (IC50 = 0.30 nM). Allosterically alters TrkB receptor conformation but does not alter BDNF binding. Prevents BDNF-induced cold allodynia in mice. Also shown to exhibit putative anxiolytic properties in mice.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 173.00 | |
5 mg | In stock | $ 392.00 | |
10 mg | In stock | $ 589.00 | |
25 mg | In stock | $ 943.00 | |
50 mg | In stock | $ 1,280.00 | |
100 mg | In stock | $ 1,720.00 |
Description | Cyclotraxin B acetate is an antagonist of TrkB receptors; inhibits BDNF-induced TrkB activity (IC50 = 0.30 nM). Allosterically alters TrkB receptor conformation but does not alter BDNF binding. Prevents BDNF-induced cold allodynia in mice. Also shown to exhibit putative anxiolytic properties in mice. |
Targets&IC50 | TrkB:0.30 nM |
Molecular Weight | 1260.42 |
Formula | C50H77N13O19S3 |
CAS No. | TP2068L |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mM
You can also refer to dose conversion for different animals. More
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Cyclotraxin B acetate(1203586-72-4 free base) TP2068L Tyrosine Kinase/Adaptors Trk receptor Cyclotraxin B acetate(1203586 72 4 free base) Cyclotraxin B acetate(1203586724 free base) inhibitor inhibit