Co-stimulatory Immune Checkpoint Proteins

Stimulating immune checkpoint proteins weaken the immune system in contrast to inhibitory pathways, and co-stimulatory molecules may fight malignant cells by enhancing the immune response. Malignant cells usually promote tumorigenesis by inhibiting the co-stimulatory pathway. Checkpoint stimulatory molecules such as OX40, GITR, ICOS, 4-1BB, CD40 play a key role in regulating T cell effector function, and activation of the co-stimulatory pathway may enhance checkpoint inhibition effect and lead to durable anti-tumor response.

Cat No.	product name / Synonyms	Species	Expression System
TMPJ-00422	OX40 Protein, Mouse, Recombinant (His) OX40 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
TMPJ-00422	OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis o...
TMPJ-00555	B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated	Human	Human Cells
TMPJ-00555	The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or C...
TMPJ-00556	B7-2 Protein, Human, Recombinant (His) B7-2 Protein, Human, Recombinant (His)	Human	Human Cells
TMPJ-00556	The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or C...
TMPJ-00615	CD27 Protein, Rhesus macaque, Recombinant (hFc) CD27 Protein, Rhesus macaque, Recombinant (hFc)	Rhesus macaque	Human Cells
TMPJ-00615	CD27 antigen, also known as CD27L receptor, T-cell activation antigen CD27, T14, S152, Tp55, TNFRSF7 and Tumor necrosis factor receptor for superfamily member 7，...
TMPJ-00616	CD27 Protein, Rhesus macaque, Recombinant (His) CD27 Protein, Rhesus macaque, Recombinant (His)	Rhesus macaque	Human Cells
TMPJ-00616	CD27 antigen, also known as CD27L receptor, T-cell activation antigen CD27, T14, S152, Tp55, TNFRSF7 and Tumor necrosis factor receptor for superfamily member 7，...
TMPJ-00630	B7-1 Protein, Cynomolgus, Recombinant (hFc) B7-1 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	Human Cells
TMPJ-00630	Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-pr...
TMPJ-00632	B7-2 Protein, Cynomolgus, Recombinant (hFc) B7-2 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	Human Cells
TMPJ-00632	T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play impo...
TMPJ-00634	CD40 Protein, Cynomolgus, Recombinant (His) CD40 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Human Cells
TMPJ-00634	CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cel...
TMPJ-00641	B7-2 Protein, Rhesus macaque, Recombinant (His) B7-2 Protein, Rhesus macaque, Recombinant (His)	Rhesus macaque	Human Cells
TMPJ-00641	T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play impo...
TMPJ-00920	CD40L Protein, Mouse, Recombinant (His) CD40L Protein, Mouse, Recombinant (His)	Mouse	Human Cells
TMPJ-00920	CD40 Ligand, also known as TNFSF5, CD154, is a type II transmembrane glycoprotein member of the TNF superfamily. Mature mouse CD40 Ligand consists of a 22 amino ...
TMPJ-00958	B7-1 Protein, Rabbit, Recombinant (His) B7-1 Protein, Rabbit, Recombinant (His)	Rabbit	Human Cells
TMPJ-00958	Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of ...
TMPJ-00959	B7-2 Protein, Rabbit, Recombinant (His) B7-2 Protein, Rabbit, Recombinant (His)	Rabbit	Human Cells
TMPJ-00959	T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play impo...
TMPJ-01420	CD40 Protein, Cynomolgus, Recombinant (hFc) CD40 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	Human Cells
TMPJ-01420	CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cel...
TMPJ-01441	OX40L Protein, Cynomolgus, Recombinant (His) OX40L Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Human Cells
TMPJ-01441	Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and...
TMPJ-01458	OX40 Protein, Cynomolgus, Recombinant (His) OX40 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Human Cells
TMPJ-01458	OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis o...
TMPK-00063	OX40 Ligand/TNFSF4 Trimer Protein, Human, Recombinant (His & Flag) OX40 Ligand/TNFSF4 Trimer Protein, Human, Recombinant (His & Flag)	Human	HEK293
TMPK-00063	Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L),which belongs to the tumor necrosis factor fam...
TMPK-00078	CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled	Human	HEK293
TMPK-00078	CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a...
TMPK-00079	CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His) CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His)	Human	HEK293
TMPK-00079	CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a...
TMPK-00080	CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	HEK293
TMPK-00080	CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a...
TMPK-00086	ICOS/CD278 Protein, Human, Recombinant (His) ICOS/CD278 Protein, Human, Recombinant (His)	Human	HEK293
TMPK-00086	Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of ...