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Oxytetracycline Hydrochloride

Catalog No. T21430 CAS 2058-46-0

Synonyms: Dalinmycin, Oxytetracycline HCl, Biosolvomycin, Dalimycin, Oxytetracycline.HCl, Oxytetracycline, Sodium Salt

Oxytetracycline Hydrochloride is a tetracycline derivative produced by Streptomyces rimosus with antimicrobial activity. It interferes with the binding of aminoacyl-tRNA to the mRNA-<a href="/target/ribosome" style="display: inline; color: #c13a36">ribosome</a> complex, resulting in preventing peptide elongation and inhibiting protein synthesis.

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Oxytetracycline Hydrochloride, CAS 2058-46-0

Pack Size	Availability	Price/USD
100 mg	In stock	$ 50.00
200 mg	In stock	$ 62.00
500 mg	In stock	$ 86.00
1 mL * 10 mM (in DMSO)	In stock	$ 55.00

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Purity: 96.68%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Oxytetracycline Hydrochloride is a tetracycline derivative produced by Streptomyces rimosus with antimicrobial activity. It interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, resulting in preventing peptide elongation and inhibiting protein synthesis.

In vivo

The 10-day effect of oxytetracycline at therapeutic doses (82.8 mg/kg bw to 1 % bw/day) was species-specific. Oxytetracycline increases the enzymatic activity of CYP3A4 in Ictalurus punctatus, increases the protein expression of CYP3A4 in Oreochromis niloticus, and depletes hepatic CYP3A4 in the latter, and also increases the relative liver weight of Morone chrysops x M. saxatilis [1]. Oxytetracycline is limited to 100 μg/kg in muscle and breast milk, 200 μg/kg in eggs, 300 μg/kg in liver, and 600 μg/kg in kidney[3].

Synonyms	Dalinmycin, Oxytetracycline HCl, Biosolvomycin, Dalimycin, Oxytetracycline.HCl, Oxytetracycline, Sodium Salt
Molecular Weight	496.89
Formula	C22H25ClN2O9
CAS No.	2058-46-0

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

H2O: Insoluble

DMSO: 100 mg/mL (201.25 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Morales-Nin B, Grau A, Pérez-Mayol S, Pastor E, Palmer M. Oxytetracycline hydrochloride vital labelling revisited: the case of Dicentrarchus labrax and Diplodus puntazzo. J Fish Biol. 2011 Mar;78(3):762-82. 2. Pickens LB, et al. Oxytetracycline biosynthesis. J Biol Chem. 2010 Sep 3;285(36):27509-15. 3. Morales-Nin B, Grau A, Pérez-Mayol S, Pastor E, Palmer M. Oxytetracycline hydrochloride vital labelling revisited: the case of Dicentrarchus labrax and Diplodus puntazzo. J Fish Biol. 2011 Mar;78(3):762-82. doi: 10.1111/j.1095-8649.2010.02887.x. PubMed PMID: 21366571. 4. López-Jornet P, Camacho-Alonso F, Martinez-Canovas A, Sidrach-Cardona M. Topical 1% oxytetracycline hydrochloride versus placebo in oral mucosa biopsy. Dermatol Surg. 2012 Jul;38(7Pt 1):1054-8.

Related compound libraries

This product is contained In the following compound libraries：

FDA-Approved & Pharmacopeia Drug Library FDA-Approved Drug Library Inhibitor Library Approved Drug Library Bioactive Compound Library Anti-Bacterial Compound Library Drug Repurposing Compound Library Orally Active Compound Library Bioactive Compounds Library Max Human Endogenous Metabolite Library

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Keywords

Oxytetracycline Hydrochloride 2058-46-0 Immunology/Inflammation Metabolism Microbiology/Virology Endogenous Metabolite Antiviral Antibacterial HSV Dalinmycin Gram-positive Antibiotic Oxytetracycline Oxytetracycline HCl Gram-negative Biosolvomycin Dalimycin Oxytetracycline.HCl Bacterial tetracycline Herpes simplex virus Inhibitor synthesis protein HSV-1 m-ribosomal Oxytetracycline, Sodium Salt inhibit aminoacil-tRNA inhibitor

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