Powder: -20°C for 3 years | In solvent: -80°C for 1 year
L-2-Hydroxyglutaric acid disodium ((S)-2-Hydroxyglutaric acid disodium) is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity(Km and Ki of 2.52 mM and 11.13 mM, respectively).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 45.00 | |
25 mg | In stock | $ 83.00 | |
50 mg | In stock | $ 136.00 | |
100 mg | In stock | $ 186.00 |
Description | L-2-Hydroxyglutaric acid disodium ((S)-2-Hydroxyglutaric acid disodium) is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity(Km and Ki of 2.52 mM and 11.13 mM, respectively). |
In vitro | L-2-hydroxyglutarate can effectively inhibit 2-oxoglutarate (2-OG) dependent dioxygenases (2OGDs), including eleven eleven translocation (TET) enzymes [2]. |
Synonyms | (S)-2-Hydroxyglutaric acid disodium |
Molecular Weight | 192.08 |
Formula | C5H6Na2O5 |
CAS No. | 63512-50-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5 mM
You can also refer to dose conversion for different animals. More
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L-2-Hydroxyglutaric acid disodium 63512-50-5 Chromatin/Epigenetic Metabolism Mitochondrial Metabolism Histone Demethylase 2-Hydroxyglutaric acid disodium L 2 Hydroxyglutaric acid disodium modifier demethylases methylation Inhibitor renal cancer 2-Hydroxyglutaric acid epigenetic L-2-Hydroxyglutaric acid inhibit histone L2Hydroxyglutaric acid disodium (S)-2-Hydroxyglutaric acid disodium inhibitor