Powder: -20°C for 3 years
In solvent: -80°C for 2 years
L-2-Hydroxyglutaric acid disodium is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity(Km and Ki of 2.52 mM and 11.13 mM, respectively).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 52.00 | |
25 mg | In stock | $ 92.00 | |
50 mg | In stock | $ 149.00 | |
100 mg | In stock | $ 201.00 |
Description | L-2-Hydroxyglutaric acid disodium is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity(Km and Ki of 2.52 mM and 11.13 mM, respectively). |
In vitro | L-2-hydroxyglutarate can effectively inhibit 2-oxoglutarate (2-OG) dependent dioxygenases (2OGDs), including eleven eleven translocation (TET) enzymes [2]. |
Synonyms | (S)-2-Hydroxyglutaric acid disodium |
Molecular Weight | 194.094 |
Formula | C5H8Na2O5 |
CAS No. | 63512-50-5 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 5 mM
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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L-2-Hydroxyglutaric acid disodium 63512-50-5 Chromatin/Epigenetic Metabolism Histone Demethylase Mitochondrial Metabolism L 2 Hydroxyglutaric acid disodium (S)-2-Hydroxyglutaric acid disodium modifier demethylases methylation Inhibitor renal cancer epigenetic inhibit histone L2Hydroxyglutaric acid disodium inhibitor