Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Transporter 2 Inhibitor.
Pack Size | Availability | Price/USD | Quantity |
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500 mg | In stock | $ 45.00 |
Description | Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Transporter 2 Inhibitor. |
In vivo | Trimethoprim acts by interfering with the bacterial dihydrofolate reductase, inhibiting the synthesis of tetrahydrofolic acid. This inhibition causes a deficiency in nucleotides essential for bacterial DNA replication, which in some instances leads to cell death due to thymineless death. |
Synonyms | NIH 204, BW 56-72, NSC-106568 |
Molecular Weight | 290.32 |
Formula | C14H18N4O3 |
CAS No. | 738-70-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (189.45 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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Trimethoprim 738-70-5 Cell Cycle/Checkpoint DNA Damage/DNA Repair Metabolism Microbiology/Virology DHFR Antibacterial DNA/RNA Synthesis Antifolate Antibiotic NIH 204 Inhibitor Shigellosis folate NSC106568 inhibit Hsps protein urinary tract infections reductase Pneumocystis pneumonia BW 56-72 Influenza Virus NSC 106568 Bacterial aggregation NSC-106568 metabolism tetrahydrofolate dihydrofolate NIH204 Antimicrobial NIH-204 inhibitor