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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T38629 | Folate-PEG3-alkyne | Folate-PEG3-alkyne | |
Folate-PEG3-alkyne is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syste... | |||
T40818 | Folate-PEG3-amine | Folate-PEG3-amine | |
Folate-PEG3-amine is a three-unit polyethylene glycol (PEG) linker, which is cleavable. This linker is specifically employed in the synthesis of antibody-drug conjugates (ADCs). | |||
T38492 | Folate-PEG2-amine | Folate-PEG2-amine | |
Folate-PEG2-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system... | |||
T21367 | Tetrahydrofolic acid | 5,6,7,8-tetrahydrofolic acid,folate-H4,Tetrahydropteroylglutamic acid,th-folate | Endogenous Metabolite |
Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) is a vitamin B9 derivative that is a common one-carbon donor in organisms and is involved in growth and metabolism. | |||
T34942 | Triglutamate folate | Pteglu3 | |
Triglutamate folate is a bioactive chemical. | |||
T25496 | Hexaglutamate folate | Pteglu6 | |
Hexaglutamate folate is a naturally occurring form of folic acid. The bioavailability of dietary folate may be limited by the need for the glutamate moieties to be deconjugated before absorption. Folate deficiency in hum... | |||
T17861 | DSPE-PEG46-Folate | Others | |
DSPE-PEG46-Folate is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system... | |||
T17984 | Folate-PEG3-azide | Others | |
Folate-PEG3-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system... | |||
T31836 | Folate sodium | Folic acid, monosodium salt,Folvite sodium | |
Folate sodium, as a member of the vitamin B family, can stimulate the hematopoietic system. Folic acid can be used in the treatment and prevention of folate deficiencies and megaloblastic anemia. | |||
T82378 | Folate-MS432 | PROTACs | |
Folate-MS432 is a PROTAC that degrades MEKs selectively in cancer cells via folate receptor-dependent pathways. | |||
T0062 | Folic acid | Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,Folacin | DNA/RNA Synthesis , Endogenous Metabolite |
Folic acid (Vitamin B9)(Vitamin M; Vitamin B9) is indispensable for the production and maintenance of new cells, for DNA/RNA synthesis. | |||
T74308 | DSPE-PEG-Folate | ||
DSPE-PEG-Folate (Mw 3350), a derivative of PEG with folic acid content, exhibits targeting capability by binding to folate receptors on cancer cells. It forms micelles/lipid bilayers, facilitating its use in targeted dru... | |||
T77274 | DSPE-PEG-Folate (MW 5000) | ||
DSPE-PEG-Folate (MW 5000), a derivative of polyethylene glycol (PEG) integrated with folic acid, demonstrates a specific targeting ability by binding to folate receptors on cancer cells. This compound forms micelles/lipi... | |||
T77270 | Cholesterol-PEG-Folate (MW 2000) | ||
Cholesterol-PEG-Folate (MW 2000), an excipient, facilitates the preparation of folate-conjugated PEG-liposomes [1]. | |||
T25358 | EC-17 free acid | EC17,EC 17,EC-17,FTIC-Folate,Folate-FTIC | |
EC17 is a FITC conjugated folic acid, also known as Folate-FITC. It also acts as an FRα-targeting agent that fluoresces at 500nm. EC17 is a conjugate consisting of fluorescein isothiocyanate (FITC) conjugated with folate... | |||
T31508 | Diopterin | Folate monoglutamate,Pteroyl diglutamic acid | |
Diopterin is a folic acid analog. | |||
T3279 | Silver sulfadiazine | Silvadene,Dermazin,Flamazine | DNA/RNA Synthesis , Antibacterial , Antibiotic |
Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity. | |||
T1153 | Trimethoprim | NIH 204,BW 56-72,NSC-106568 | DHFR , DNA/RNA Synthesis , Antifolate , Antibacterial , Antibiotic |
Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Tra... | |||
T7593 | Levomefolate calcium | Antifolate | |
Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements. | |||
T7598 | Calcium N5-methyltetrahydrofolate | NSC173328 | Others , Antifolate |
Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers |