secretory — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T13206	Tris(2,4-di-tert-butylphenyl)phosphate		Phospholipase
	Tris(2,4-di-tert-butylphenyl)phosphate is a natural compound isolated from Vitex negundo L. with anti-inflammatory activity.		Phospholipase
T8599	Betazole dihydrochloride	Betazole hydrochloride	Histamine Receptor
	Betazole dihydrochloride (Betazole hydrochloride) is an agonist of H2 receptor.		Histamine Receptor
T2044	Varespladib	LY315920	Phospholipase
	Varespladib (LY315920), a specific and effective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor(IC50=7 nM), has been investigated for the treatment and prevention of sickle cell disease, vaso-occlusiv...		Phospholipase
T22665	PD 128042	CI 976	Acyltransferase
	PD 128042 (CI 976) is a potent orally active and selective ACAT inhibitor(IC50: 73 nM) and a potent lysophospholipid acyltransferase(LPAT) inhibitor. CI 976 inhibits Golgi-associated LPAT activity (IC50: 15 μM) and multi...		Acyltransferase
T6928	Pantoprazole	SKF96022,BY1023	Apoptosis , Proton pump , Autophagy
	Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.		Apoptosis , Proton pump , Autophagy
T0161	Pantoprazole Sodium Hydrate	SKF96022 sodium hydrate,BY1023 (sodium hydrate),SKF96022 (sodium hydrate)	Apoptosis , Potassium Channel , Proton pump , Autophagy
	Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.		Apoptosis , Potassium Channel , Proton pump , Autophagy
T6929	Pantoprazole sodium	Pantecta,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),BY-1023 sodium,Pantoloc	Apoptosis , Others , Proton pump , HIF , Autophagy
	Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, weak base that crosses the parietal cell membrane and enters...		Apoptosis , Others , Proton pump , HIF , Autophagy
T17218	Varespladib methyl	A-002,LY333013	Others , Phospholipase
	Varespladib methyl (LY333013), a bioavailable prodrug of Varespladib, is a selective group II secretory phospholipase A2 inhibitor.		Others , Phospholipase
T4192	Hnps-PLA Inhibitor		Phospholipase , LTR
	Hnps-PLA Inhibitor is an inhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA).		Phospholipase , LTR
TN1419	Rhamnetin	beta-Rhamnocitrin	Others , Phospholipase
	Rhamnetin (beta-Rhamnocitrin), a quercetin derivative found in Coriandrum sativum, has antioxidant and anti-inflammatory activities. Rhamnetin inhibits secretory phospholipase A2.		Others , Phospholipase
T2486	IOWH-032	IOWH032,IOWH 032	CFTR , Autophagy
	IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.		CFTR , Autophagy
T0594	Diphenmanil methylsulfate	Diphemanil mesylate,Diphemanil Methylsulfate	AChR
	Diphenmanil methylsulfate (Diphemanil mesylate), a quaternary ammonium anticholinergic, binds muscarinic acetylcholine receptors and thus decreases secretory excretion of stomach acids, sweat, and saliva.		AChR
T16865	SCH28080		ATPase , Proton pump
	SCH28080 is a reversible and K+-competitive inhibitor of gastric H+/K+-ATPase with an IC50 value of 20 nM (rabbit microsomal membrane).SCH28080 is a potent inhibitor of acid secretion in vivo with anti-ulcer activity, an...		ATPase , Proton pump
TCS1772	Dehydroabietic acid	Dehydroabietate	Antifection
	1. Dehydroabietic acid (Dehydroabietate) (DAA) is an EBV-EA activation inhibitor. 2. DAA is a useful food-derived compound for treating obesity-related diseases, by decreasing plasma glucose, insulin levels, plasma trigl...		Antifection
T1756	Ilaprazole sodium	IY-81149 sodium	Proton pump , TOPK
	Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environment of the secretory canaliculus...		Proton pump , TOPK
T23547	YM 26734		Others
	Competitive inhibitor of secretory phospholipase A2 (sPLA2)		Others
T29056	UK-9040	UK9040,UK 9040
	UK-9040 inhibits gastric secretory.
T30290	Bam 1745	Bam1745,Pyroglutamyl peptide bam-1745,Bam-1745
	Bam 1745 is a significant adrenomedullary secretory vesicles component.
T27539	Hexocyclium metilsulfate	AB803,AB-803,Traline,AB 803
	Hexocyclium metilsulfate has anti-gastric secretory effects in humans.
T20755	Trimegestone	RU27987,RU-27987,RU 27987
	Trimegestone, a highly effective oral progestogen, is used for endometrial protection, all doses inducing secretory endometrial transformation.