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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14319 | Aripiprazole Lauroxil | Dopamine Receptor , 5-HT Receptor | |
Aripiprazole lauroxil, the N-acyloxymethyl prodrug form of aripiprazole, a long-acting injectable (LAI) antipsychotic. Aripiprazole lauroxil is cleaved by esterases in vivo to N-hydroxymethyl aripiprazole (lauric acid), ... | |||
T8862 | ML 254 | GluR | |
ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricerca profile, and suitable dystrophia myotonica protein kinas... | |||
T10232 | Acetophenazine dimaleate | Dopamine Receptor | |
Acetophenazine dimaleate is an antipsychotic agent, effective in anxious depression. Acetophenazine dimaleate primarily targets the dopamine D2 receptor. | |||
T21629 | Loxapine | Dopamine Receptor , 5-HT Receptor | |
Loxapine is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent,used primarily in the treatment of schizophrenia. The drug is a member of the dibenzoxazepine class ... | |||
T9183 | Ralmitaront | RO6889450 | Others |
Ralmitaront (RO6889450) is a potent, orally active partial agonist of the trace amine-associated receptor 1 (TAAR1). | |||
T13189 | TP-10 | PDE | |
TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM. | |||
T11095L | DREADD agonist 21 | 5-HT Receptor , Adrenergic Receptor , AChR , Histamine Receptor | |
DREADD agonist 21 is a potent agonist of human muscarinic acetylcholine M3 receptors (EC50=1.7 nM). | |||
T5183 | AUT1 | Potassium Channel | |
AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a). | |||
T29137 | VU0453595 | VU 0453595,VU-0453595 | AChR |
VU0453595 is a M1 positive allosteric modulator (PAM). | |||
T14830 | Bromperidol | R-11333 | 5-HT Receptor |
Bromperidol (R-11333) is a butyrophenone derivative and it is a potent and long-acting neuroleptic. Which is used as an antipsychotic in the treatment of schizophrenia. | |||
T7549 | Talnetant | SB 223412 | Neurokinin receptor |
Talnetant (SB 223412) is a selective, competitive, brain-penetrant NK3 receptor antagonist with the ability to modulate mesolimbic and mesocortical dopaminergic neurotransmission | |||
T23348 | SEN12333 | SEN 12333 | AChR |
SEN12333 is an α7 nicotinic acetylcholine receptor (nAChR) agonist | |||
T9694 | Emraclidine | CVL-231 | AChR |
Emraclidine (CVL-231) is a muscarinic M4 receptor positive allosteric modulator and can be used in neurological diseases studies. | |||
T1539 | Iloperidone | HP 873 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Iloperidone (HP 873) is an atypical antipsychotic agent that is used for treatment of schizophrenia. | |||
T15260 | Evenamide | NW-3509 | Sodium Channel |
Evenamide (NW-3509) is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness. | |||
T4195 | Betahistine | PT 9 base,Vasomotal,Serc base | Histamine Receptor |
Betahistine (Vasomotal) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. Betahisti... | |||
T11722 | JNJ-37822681 dihydrochloride | Dopamine Receptor | |
JNJ-37822681 has potential for the treatment of schizophrenia and bipolar disorder.JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate b... | |||
T0076 | Paliperidone | 9-hydroxyrisperidone | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Histamine Receptor |
Paliperidone (9-hydroxyrisperidone)(Invega) is used as an atypical antipsychotic. It applies to the acute and maintenance treatment of schizophrenia. Chemically, paliperidone is the primary active metabolite of the older... | |||
T9317 | TAK-041 | NBI-1065846 | GPR |
TAK-041 (NBI-1065846) is a potent and selective GPR139 agonist. | |||
T0246 | Betahistine dihydrochloride | PT-9,Betahistine 2HCl | Histamine Receptor |
Betahistine dihydrochloride (Betahistine 2HCl) is a histamine analog and H1 receptor agonist that serves as a vasodilator. |