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Search Results for " schizophrenia "

20

Compounds

Cat No. Product Name Synonyms Targets
T14319 Aripiprazole Lauroxil Dopamine Receptor , 5-HT Receptor
Aripiprazole lauroxil, the N-acyloxymethyl prodrug form of aripiprazole, a long-acting injectable (LAI) antipsychotic. Aripiprazole lauroxil is cleaved by esterases in vivo to N-hydroxymethyl aripiprazole (lauric acid), ...
T8862 ML 254 GluR
ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricerca profile, and suitable dystrophia myotonica protein kinas...
T10232 Acetophenazine dimaleate Dopamine Receptor
Acetophenazine dimaleate is an antipsychotic agent, effective in anxious depression. Acetophenazine dimaleate primarily targets the dopamine D2 receptor.
T21629 Loxapine Dopamine Receptor , 5-HT Receptor
Loxapine is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent,used primarily in the treatment of schizophrenia. The drug is a member of the dibenzoxazepine class ...
T9183 Ralmitaront RO6889450 Others
Ralmitaront (RO6889450) is a potent, orally active partial agonist of the trace amine-associated receptor 1 (TAAR1).
T13189 TP-10 PDE
TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM.
T11095L DREADD agonist 21 5-HT Receptor , Adrenergic Receptor , AChR , Histamine Receptor
DREADD agonist 21 is a potent agonist of human muscarinic acetylcholine M3 receptors (EC50=1.7 nM).
T5183 AUT1 Potassium Channel
AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).
T29137 VU0453595 VU 0453595,VU-0453595 AChR
VU0453595 is a M1 positive allosteric modulator (PAM).
T14830 Bromperidol R-11333 5-HT Receptor
Bromperidol (R-11333) is a butyrophenone derivative and it is a potent and long-acting neuroleptic. Which is used as an antipsychotic in the treatment of schizophrenia.
T7549 Talnetant SB 223412 Neurokinin receptor
Talnetant (SB 223412) is a selective, competitive, brain-penetrant NK3 receptor antagonist with the ability to modulate mesolimbic and mesocortical dopaminergic neurotransmission
T23348 SEN12333 SEN 12333 AChR
SEN12333 is an α7 nicotinic acetylcholine receptor (nAChR) agonist
T9694 Emraclidine CVL-231 AChR
Emraclidine (CVL-231) is a muscarinic M4 receptor positive allosteric modulator and can be used in neurological diseases studies.
T1539 Iloperidone HP 873 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
Iloperidone (HP 873) is an atypical antipsychotic agent that is used for treatment of schizophrenia.
T15260 Evenamide NW-3509 Sodium Channel
Evenamide (NW-3509) is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.
T4195 Betahistine PT 9 base,Vasomotal,Serc base Histamine Receptor
Betahistine (Vasomotal) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. Betahisti...
T11722 JNJ-37822681 dihydrochloride Dopamine Receptor
JNJ-37822681 has potential for the treatment of schizophrenia and bipolar disorder.JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate b...
T0076 Paliperidone 9-hydroxyrisperidone Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Histamine Receptor
Paliperidone (9-hydroxyrisperidone)(Invega) is used as an atypical antipsychotic. It applies to the acute and maintenance treatment of schizophrenia. Chemically, paliperidone is the primary active metabolite of the older...
T9317 TAK-041 NBI-1065846 GPR
TAK-041 (NBI-1065846) is a potent and selective GPR139 agonist.
T0246 Betahistine dihydrochloride PT-9,Betahistine 2HCl Histamine Receptor
Betahistine dihydrochloride (Betahistine 2HCl) is a histamine analog and H1 receptor agonist that serves as a vasodilator.
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TargetMol