Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 93.00 | |
5 mg | In stock | $ 197.00 | |
10 mg | In stock | $ 293.00 | |
25 mg | In stock | $ 512.00 | |
50 mg | In stock | $ 743.00 | |
100 mg | In stock | $ 1,050.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 229.00 |
Description | TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM. |
In vivo | TP-10 is active in the mouse behavioral model for positive symptoms. TP-10 demonstrates good in vitro and in vivo activity with extremely high intrinsic clearance (CLint) of t>1000 mL/min/kg in mouse liver microsomes (MLM) in assay[1]. |
Molecular Weight | 460.45 |
Formula | C26H19F3N4O |
CAS No. | 898563-00-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 95 mg/mL (206.32 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TP-10 898563-00-3 Metabolism PDE schizophrenia U-87 MG cGMP inhibit disorder Inhibitor cAMP TP10 reactive oxygen TP 10 Phosphodiesterase (PDE) pCREB-LI inhibitor