pylori — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T15500	HPi1		Others , Antibacterial
	HPi1 is a selective and orally active antimicrobial against Helicobacter pylori (IC50: 0.24 μM and a MIC of 0.08-0.16 μg/mL). HPi1 is inactive against other Xaliproden, including the gut commensals, Lactobacillus reuteri...		Others , Antibacterial
T1734	Rabeprazole Sulfide	Rabeprazole Related Compound E	Proton pump , Antibacterial
	Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors.		Proton pump , Antibacterial
T34093	PNNP	p NNP,p-Nitrophenyl phosphate,p-NNP,Nitrophenylphosphate	Carbonic Anhydrase
	pNNP (Nitrophenylphosphate) can be used as a substrate for the PP2C assay. pNNP inhibits β-carbonic anhydrase and α-carbonate dehydrogenase, as well as H. pylori Helicobacter pylori. pNNP is a weakly active, tissue-nonsp...		Carbonic Anhydrase
TN1213	2-(Hydroxymethyl)anthraquinone		Anti-infection
	2-(Hydroxymethyl)anthraquinone exhibits strong activity against Helicobacter pylori ATCC 43504 at 0.01 mg/disc.		Anti-infection
TN5173	Trichorabdal A		Antifection
	Trichorabdal A shows a very strong in vitro antibacterial activity against Helicobacter pylori.		Antifection
T6415	Bismuth Subcitrate Potassium		Others , Antibacterial , Antibiotic
	Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection.		Others , Antibacterial , Antibiotic
TN1733	Hesperetin 7-O-glucoside		Anti-infection , Antibacterial , HMG-CoA Reductase
	Hesperetin 7-O-glucoside and prunin are direct precursors of naringin and neohesperidin, respectively, in C. aurantium. Hesperetin 7-O-glucoside shows inhibition of human HMG-CoA reductase, it also exhibits effective inh...		Anti-infection , Antibacterial , HMG-CoA Reductase
T1562	Rebamipide	Proamipide,OPC12759	Free radical scavengers , COX , Prostaglandin Receptor
	Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis ...		Free radical scavengers , COX , Prostaglandin Receptor
T26288	Clovamide	trans-Clovamide,N-trans-Caffeoy-L-dopa	Apoptosis , Influenza Virus , ROS , Antibacterial
	Trans-Clovamide (trans-Clovamide) is a naturally occurring caffeoyl conjugate identified in the antioxidant polyphenolic fraction of cocoa (T. cacao L.) Trans-Clovamide is a potent antioxidantand that has shown neuroprot...		Apoptosis , Influenza Virus , ROS , Antibacterial
T2S1865	Octyl gallate	Gallic acid octyl ester,n-Octylgallate,Octyl 3,4,5-trihydroxybenzoate,Progallin O,Stabilizer GA-8	Antioxidant , Influenza Virus , Reactive Oxygen Species , Antibacterial , Antifungal , HSV
	1. Octyl Gallate is an antioxidant approved by the US Food and Drug Administration (FDA) as a food additive. 2. Octyl Gallate has antimetastatic activity. 3. Octyl Gallate shows antimicrobial activity against H. pylori, ...
T6S1684	8-Gingerol		Antioxidant , Antibacterial , TRP/TRPV Channel
	1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristic...		Antioxidant , Antibacterial , TRP/TRPV Channel
T13970	Xinjiachalcone A		Others
	Xinjiachalcone A is a natural product isolated from Glycyrrhiza inflata Batalin. Xinjiachalcone A shows both a low MIC and a strong bactericidal activity against H. pylori(MIC : 12.5 to 50 µM, seventeen H. pylori strains...		Others
T27375	FR-182024	FR 182024,FR182024
	FR-182024 is a novel cephem derivative, it has potent anti-Helicobacter pylori activity.
T27378	FR-193879	FR193879
	FR-193879 is an efficacious cephem derivative, it has extremely potent therapeutic efficacy against H. pylori.
TN1302	6,8-Diprenylorobol		Others , HIV Protease , Antifection
	6,8-Diprenylorobol possesses weaker anti-H. pylori activity, it may be a useful chemopreventive agent for peptic ulcer or gastric cancer in H. pylori-infected individuals.		Others , HIV Protease , Antifection
T3831	Licoricone		Antifection
	Licoricone exhibits anti-helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains.		Antifection
TN3852	Dihydrolicoisoflavone		Antifection
	Dihydrolicoisoflavone A possesses weaker anti-H. pylori activity, it may be useful chemopreventive agents for peptic ulcer or gastric cancer in H. pylori-infected individuals.		Antifection
TN1699	Glyasperin D		Antifection
	Glyasperin D possesses weak anti-Helicobacter pylori activity.		Antifection
T28834	Spirolaxine
	Spirolaxine, a natural product isolated from Sporotrichum laxum ATCC 15155, has shown a variety of biological activities including promising anti-Helicobacter pylori property.
TN3318	9-Hydroxy-alpha-lapachone		Antifection
	9-Hydroxy-alpha-lapachone can highly inhibit the growth of H. pylori, it exhibits potent inhibitory activity against H. pylori Cystathionine gamma-synthase, with IC(50) values of 4.64 microM. It may have anti-inflammator...		Antifection