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Search Results for " pressure-lowering "

20

Compounds

Cat No. Product Name Synonyms Targets
T0022 Taurine 2-Aminoethanesulfonic acid LDL , Endogenous Metabolite , Autophagy
Taurine (2-Aminoethanesulfonic acid), an organic acid, is distributed in various animal tissues.
T0106 Methazolamide L584601,CL 8490 Carbonic Anhydrase
Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
T12478L Pinacidil S 1230,P 1134,S-1230,P-1134,P1134 Potassium Channel
Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure and peripheral resistance and producing fluid retention.
T4661 PKG drug G1 PKA
PKG drug G1 targets PKG Iα C42. PKG drug G1 can couple to vasodilation and blood pressure lowering by a C42 PKG Iα-independent mechanism.
T6S0654 Isocorynoxeine 7-Isocorynoxeine 5-HT Receptor
1. Isocorynoxeine (7-Isocorynoxeine) shows the effects of lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage. 2. Isocorynoxeine exhibits a significant neuroprotective effect ...
T2782L Catharanthine Tartrate(2468-21-5(free base)) Calcium Channel
Catharanthine Tartrate is a natural product isolated from Madagascar periwinkle, Catharanthine Tartrate inhibits voltage-operated L-type Ca2+ channel, with anti-cancer and blood pressure-lowering activity
T3744 Veratric acid Veratrumenoic acid,3,4-Dimethoxybenzoic acid Reactive Oxygen Species , COX
Veratric acid (3,4-Dimethoxybenzoic acid) is a simple benzoic acid derived from plants and fruits with anti-oxidant, anti-inflammation and blood pressure-lowering effects.
T15718 Latanoprost acid GPR
Latanoprost acid is a selective agonist of prostanoid receptors and inhibits RANKL-induced osteoclastogenesis and function through the inhibition of c-fos/NFATc1 pathway. Latanoprost acid can be used in studies about low...
T3332 Isosteviol (-)-Isosteviol IL Receptor , Potassium Channel , TNF , NF-κB , Reactive Oxygen Species , COX , Topoisomerase
Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside and its hydrolysis products, steviol, isosteviol and stevio...
T26453 A 81282 A81282,A-81282,Abbott 81282,Abbott-81282
A 81282 is a selective antagonist of angiotensin receptors. It has the activity of lowering blood pressure.
T25483 H-0106 Dihydrochloride H 0106 2HCl,H0106 2HCl,H0106 Dihydrochloride
H-0106 Dihydrochloride is an inhibitor of ROCK that acts by applying strong intraocular pressure (IOP)-lowering effects into the eyes of monkeys.
T25482 H-0104 Dihydrochloride H0104 Dihydrochloride,H0104 2HCl,H 0104 Dihydrochloride,H 0104 2HCl,H-0104 2HCl
H-0104 Dihydrochloride is an inhibitor of ROCK that acts by applying potent intraocular pressure (IOP)-lowering effects into the eyes of monkeys.
TN2350 Pingpeimine A Others
Pingpeimine A has the effect of expectorating and lowering blood pressure. Derived from Fritillaria sibiricum.
T81915 LPP Tripeptide
LPP Tripeptide, a blood pressure-lowering tripeptide, is utilized in hypertension research [1].
T0112L Diltiazem Diltiazem free base,Dilticard,CRD-401,CRD401,Dilzen,CRD 401
Diltiazem is a non-dihydropyridine (non-DHP) calcium channel blocker that relaxes the smooth muscle in arterial walls, thus opening (dilating) arteries, allowing easier blood flow, and lowering blood pressure, and is use...
T76499 Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine
Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine, is a peptide composed of 4 amino acids recognized for its blood pressure-lowering properties and functions as an angiotensin-converting enzyme (ACE) inhibitor. This...
T68098 Midaglizole (±)-DG5128 free base,DG5128 free base,(±)-DG5128 free base ; DG5128 free base
Midaglizole ((±)-DG5128 free base, DG5128 free base) is a powerful α2-adrenoceptor antagonist that acts as a hypoglycemic agent by increasing blood pressure and lowering blood glucose levels in vivo.
T39063 Azilsartan mepixetil
Azilsartan mepixetil is a potent angiotensin II receptor antagonist with enhanced efficacy and prolonged duration of action. It exhibits more prominent and sustained effects in lowering blood pressure and heart rate, whi...
T16388 Omidenepag isopropyl Prostaglandin Receptor
Omidenepag isopropyl is converted to the active product Omidenepag during corneal penetration. Omidenepag isopropyl is a selective EP2 receptor agonist. Omidenepag isopropyl displays only a weak affinity for EP1, EP2, an...
T78624 OPC-163493 Reactive Oxygen Species
OPC-163493 is an orally active, liver-targeted mitochondrial uncoupling agent that diminishes Δψ (delta psi) and mitochondrial ROS (reactive oxygen species) production. This compound demonstrates antidiabetic properties ...

Compounds

Taurine
T0022
Synonym: 2-Aminoethanesulfonic acid
Target: LDL, Endogenous Metabolite, Autophagy
Methazolamide
T0106
Synonym: L584601,CL 8490
Target: Carbonic Anhydrase
Pinacidil
T12478L
Synonym: S 1230,P 1134,S-1230,P-1134,P1134
Target: Potassium Channel
PKG drug G1
T4661
Synonym:
Target: PKA
Isocorynoxeine
T6S0654
Synonym: 7-Isocorynoxeine
Target: 5-HT Receptor
Catharanthine Tartrate(2468-21-5(free base))
T2782L
Synonym:
Target: Calcium Channel
Veratric acid
T3744
Synonym: Veratrumenoic acid,3,4-Dimethoxybenzoic acid
Target: Reactive Oxygen Species, COX
Latanoprost acid
T15718
Synonym:
Target: GPR
Isosteviol
T3332
Synonym: (-)-Isosteviol
Target: IL Receptor, Potassium Channel, TNF, NF-κB, Reactive Oxygen Species, COX, Topoisomerase
A 81282
T26453
Synonym: A81282,A-81282,Abbott 81282,Abbott-81282
Target:
H-0106 Dihydrochloride
T25483
Synonym: H 0106 2HCl,H0106 2HCl,H0106 Dihydrochloride
Target:
H-0104 Dihydrochloride
T25482
Synonym: H0104 Dihydrochloride,H0104 2HCl,H 0104 Dihydrochloride,H 0104 2HCl,H-0104 2HCl
Target:
Pingpeimine A
TN2350
Synonym:
Target: Others
LPP Tripeptide
T81915
Synonym:
Target:
Diltiazem
T0112L
Synonym: Diltiazem free base,Dilticard,CRD-401,CRD401,Dilzen,CRD 401
Target:
Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine
T76499
Synonym:
Target:
Midaglizole
T68098
Synonym: (±)-DG5128 free base,DG5128 free base,(±)-DG5128 free base ; DG5128 free base
Target:
Azilsartan mepixetil
T39063
Synonym:
Target:
Omidenepag isopropyl
T16388
Synonym:
Target: Prostaglandin Receptor
OPC-163493
T78624
Synonym:
Target: Reactive Oxygen Species
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TargetMol