Search Result

Search Results for " pog "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T4978	Sarpogrelate hydrochloride	MCI-9042	5-HT Receptor
	Sarpogrelate hydrochloride (MCI-9042) , a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD. Target: 5-HT2 Recepter Sarpogrelate is a drug which acts as an antagonist at ...		5-HT Receptor
T25572	Ketohypoglycin	Methylenecyclopropylpyruvate
	Ketohypoglycin has been utilized to study the inhibition of gluconeogenesis in isolated rat liver cells.
T13459	(+)-Apogossypol	Apogossypol,NSC736630	Others
	(+)-Apogossypol is an antagonist of pan-BCL-2. (+)-Apogossypol binds to Mcl-1(Bcl-2 and Bcl-xL with EC50s of 2.6, 2.8 and 3.69 µM, respectively).		Others
T125277	Hypoglaunine A

T28783	Sipoglitazar	TAK654,TAK 654,TAK-654
	Sipoglitazar, a PPARγ agonist, is used potentially for the treatment of diabetes.
T19367	Hypoglycemic agent 1		Others
	Hypoglycemic agent 1 has an action for lowering blood sugar. It acts as a therapeutic and/or prophylactic agent for diabetes.		Others
T70874	Vipoglanstat
	Vipoglanstat is a prostaglandin E synthase inhibitor and an anti-inflammatory. Vipoglanstat ameliorates leukocyte infiltration and lung injury resulting from both endotoxin-induced and sepsis-induced lung injury.
T62374	Sarpogrelate
	Sarpogrelate (MCI-9042) is a new, orally active, specific 5-HT2 receptor antagonist. sarpogrelate increases platelet aggregation, has a haemostatic effect and can be used in the study of berghett's disease.
T21786	Apogossypolone (ApoG2)
	Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins with K i values of 35, 25 and 660 nM for Bcl-2, Mcl-1 and Bcl-X L, respe...
T126059	Ophiopogonanone B
	Ophiopogonanone B is a useful organic compound for research related to life sciences and the catalog number is T126059.
T123875	Ophiopogonin B sulfate
	Ophiopogonin B sulfate is a useful organic compound for research related to life sciences and the catalog number is T123875.
T32287	Jegosapogenol A	Jegosapogenol,Giganteumgenin M,Proschiwalligenin PB1,Careyagenol A,Saniculagenin D
	Jegosapogenol A is a type of triterpenoid. Triterpenoids are terpene molecules containing six isoprene units. Barringtogenol C is a very weakly acidic compound (based on its pKa) and practically insoluble (in water). Bar...
T13091	Taspoglutide	R1583,BIM51077,ITM077	Others
	Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist(EC50 value of 0.06 nM),and for treatment of type 2 diabetes		Others

Compounds

Sarpogrelate hydrochloride

T4978

Synonym: MCI-9042

Target: 5-HT Receptor

Ketohypoglycin

T25572

Synonym: Methylenecyclopropylpyruvate

Target:

(+)-Apogossypol

T13459

Synonym: Apogossypol,NSC736630

Synonym: TAK654,TAK 654,TAK-654

Apogossypolone (ApoG2)

Ophiopogonin B sulfate

Synonym: Jegosapogenol,Giganteumgenin M,Proschiwalligenin PB1,Careyagenol A,Saniculagenin D

Target:

Taspoglutide

T13091

Synonym: R1583,BIM51077,ITM077

Target: Others

Cat No.	Product Name	Synonyms	Targets
TN1071	Ophiopogonin D'		Sirtuin , UGT
	Ophiopogonin D' can activate SIRT1 in a dose-dependent manner. Ophiopogonin D' also noncompetitively inhibits UGT1A6 and UGT1A10.		Sirtuin , UGT
T5S1252	Prosapogenin A	Progenin III	Apoptosis , Others
	Prosapogenin A (Progenin III) has anticancer activity.		Apoptosis , Others
T5S1261	Methylophiopogonanone B		Ras
	1. Methylophiopogonanone B (MOPB) induces cell morphological change and Rho activation via melanocyte dendrite retraction and stress fiber formation.		Ras
T6S1255	Ophiopogonin-D		ROS
	Ophiopogonin D(OPD) significantly inhibited the in vitro and in vivo growth of prostate cells via RIPK1, OPD may be developed as a potential anti-prostate cancer agent.		ROS
T5S1262	Methylophiopogonanone A		Others
	1. Methylophiopogonanone A has anti-inflammatory and anti-oxidative properties. 2. Methylophiopogonanone A has therapeutic potential against cerebral I/R injury through its ability to attenuate BBB disruption by regulati...		Others
T5701	OPHIOPOGONIN D		RAAS , Calcium Channel , NF-κB , PPAR
	Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.		RAAS , Calcium Channel , NF-κB , PPAR
T2733	Sarsasapogenin	Parigenin,Sarsagenin	Apoptosis , NF-κB , Endogenous Metabolite
	Sarsasapogenin (Parigenin) is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin. It is named after sarsaparilla (Smilax sp.), a family of climbing plants found in subtropical regions. It was one o...		Apoptosis , NF-κB , Endogenous Metabolite
T4244	Methylophiopogonone A		Others
	Methylophiopogonone A, an isoflavone isolated from the roots of Ophiopogon japonicus, exhibits anti-inflammatory properties.		Others
T4S0867	Pogostone	DHELWANGIN	Apoptosis , Antibacterial , Autophagy
	1. Pogostone (DHELWANGIN) possesses potent anti-bacterial and anti-fungal activities, such as gram negative bacteria , gram positive bacteria, Escherichia coli. 2. Pogostone exhibits an immunosuppressive property by dire...		Apoptosis , Antibacterial , Autophagy
TN2225	Soyasapogenol B		Apoptosis , Autophagy
	Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.		Apoptosis , Autophagy
TMA2212	Ophiopogonoside A		Others
	Ophiopogonoside A is a natural product of Ophiopogon, Liliaceae. The catalog number is TMA2212 and the CAS number is 791849-22-4. Ophiopogonoside A can be used as a reference standard.		Others
T3789	Ophiopogonin B		Others
	Ophiopogonin B has antitumor activity and is a prospective inhibitor of PI3K/Akt.		Others
T81602	Ophiopogonin R
	Ophiopogonin R (compound 3), a steroid saponin, was isolated and purified from natural ophiopogonin and demonstrated no cytotoxicity against five human tumor cell lines (HepG2, HLE, BEL7402, BEL7403, and Hela) [1].
T83266	6-Formyl-isoophiopogonanone B
	6-Formyl-isoophiopogonanone B, a homoisoflavonoid, can be isolated from the species Ophiopogon japonicus [1].
TN5470	6-Aldehydo-isoophiopogonone A
	6-Aldehydo-isoophiopogonone A is a natural product of Ophiopogon, Liliaceae. The catalog number is TN5470 and the CAS number is 112500-90-0. 6-Aldehydo-isoophiopogonone A can be used as a reference standard.
TN2014	Ophiopogonanone C		Others
	Ophiopogonanone C is a natural product of Ophiopogon, Liliaceae. The catalog number is TN2014 and the CAS number is 477336-75-7. Ophiopogonanone C can be used as a reference standard.		Others
TN2227	Soyasapogenol D		Others
	Soyasapogenol D is a natural product		Others
TN6876	Ophiopogonanone D
	Ophiopogonanone D is a natural product.
T81094	Steppogenin-7,4'-di-O-β-D-glucoside
	Steppogenin-7,4'-di-O-β-D-glucoside, a natural compound extractable from the roots of Morus nigra [1], is characterized by its unique structural composition.
T81601	Ophiopogonone C
	Ophiopogonone C (compound 3), an isoflavone, has been isolated from the ethanol extract of the tubers of Ophiopogon japonicus [1].
TN2013	Ophiopogonanone A		Others
	Ophiopogonanone A has oxygen free radicals(OFRs) scavenging effects, it can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro.		Others
TN2016	Ophiopogonin A		Others
	Ophiopogonin A is a natural product		Others
T3S1253	Cixiophiopogon A		Others
	Cixiophiopogon A is a natural product from Ophiopogon japonicus.		Others
TN2224	Soyasapogenol A		TNF
	Soyasapogenol A shows estrogenic and hepatoprotective activities, it directly prevents apoptosis of hepatocytes, and secondly, inhibits the elevation of plasma TNF-α±, which consequently resulted in the prevention of liv...		TNF
TN2104	Prosapogenin CP6		Others
	Prosapogenin CP6 is a natural product		Others
TN6273	Soyasapogenol A 21-O-α-L-rhamnopyranoside
	Soyasapogenol A 21-O-α-L-rhamnopyranoside is a natural product for research related to life sciences. The catalog number is TN6273 and the CAS number is 2067321-88-2.
TN2015	Ophiopogonanone E		Others
	Ophiopogonanone E has oxygen free radicals(OFRs) scavenging effects, it can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro.		Others
T23184	Presapogenin CP4		Others
	Presapogenin CP4 extracted from Anemone hupehensis.		Others
TN1304	6-Formyl-isoophiopogonanone A	6-Aldehydoisoophiopogonanone A	Others
	6-Aldehydoisoophiopogonanone A is a natural product from Ophiopogon japonicus.		Others
T75692	Hypoglaunine D
	Hypoglaunine D, an analogue of Triptonine B, serves as an anti-HIV compound by inhibiting HIV replication in H9 lymphocytes, demonstrating an efficacy with an EC50 value of 22 μg/ml [1].
TN4715	Ophiopogonanone F		Others
	Ophiopogonanone F can be used for preparing a drug for resisting hepatocellular injury.		Others
T83271	6-Aldehydoisoophiopogonone B
	Compound 24, also known as 6-Aldehydoisoophiopogonone B, is a homoisoflavonoid extractable from Ophiopogon japonicus [1].
TN2226	Soyasapogenol C		Others
	Soyasapogenol C is a natural product		Others
T40086	Ophiopogonside A
	Ophiopogonside A is a naturally occurring compound derived from ophiopogon japonicas, with demonstrated anti-cancer activity.
TN1050	Methylophiopogonone B		Others
	Methylophiopogonone B is a natural product		Others
TN6846	Ophiopogonone A
	ophiopogonone A is a natural product.
TN5448	Steppogenin	Norartocarpanone
	Steppogenin exhibits significant tyrosinase inhibition activity, ;it also shows strong mushroom tyrosinase inhibitory activity with IC(50) values lower than 50 microM, more potent than kojic acid (IC(50) = 71.6 microM), ...
T13805	Ophiopogonin C	Ophiopogonin C	Others
	Ophiopogonin C is a natural product isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside.		Others
T33926	Penupogenin
	Penupogenin is a steroidal aglycone isolated from the roots of Cynanchum auriculatum.

Natural Products

Synonym: Progenin III

Target: Apoptosis, Others

Methylophiopogonanone B

Methylophiopogonanone A

Target: RAAS, Calcium Channel, NF-κB, PPAR

Sarsasapogenin

T2733

Synonym: Parigenin,Sarsagenin

Target: Apoptosis, NF-κB, Endogenous Metabolite

Methylophiopogonone A

Target: Apoptosis, Antibacterial, Autophagy

Soyasapogenol B

TN2225

Synonym:

Target: Apoptosis, Autophagy

6-Formyl-isoophiopogonanone B

T83266

Synonym:

Target:

6-Aldehydo-isoophiopogonone A

Steppogenin-7,4'-di-O-β-D-glucoside

Soyasapogenol A 21-O-α-L-rhamnopyranoside

6-Formyl-isoophiopogonanone A

TN1304

Synonym: 6-Aldehydoisoophiopogonanone A

6-Aldehydoisoophiopogonone B

Methylophiopogonone B

Synonym: Norartocarpanone

Target:

Ophiopogonin C

T13805

Synonym: Ophiopogonin C

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02390	SSPA Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Stringent starvation protein A (ssPA), a member of the GST superfamily, is an RNA polymerase-associated transcriptional activator for the lytic development of phage P1 and is essential for stationary phase-induced acid t...
TMPY-06872	Ara h 9 Protein, Arachis hypogaea, Recombinant	Arachis hypogaea	P. pastoris (Yeast)
	Ara h 9 Protein, Arachis hypogaea, Recombinant is expressed in P. pastoris yeast expression system. The predicted molecular weight is 16.34 kDa.
TMPY-06670	Ara h 3.01 Protein, Arachis hypogaea, Recombinant	Arachis hypogaea	E. coli
	Ara h 3.01 Protein, Arachis hypogaea, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 59.3 kDa.
TMPH-00118	Arachin Arah3 isoform Protein, Arachis hypogaea, Recombinant (His)	Arachis hypogaea	E. coli
	N/A. Arachin Arah3 isoform Protein, Arachis hypogaea, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 62.5 kDa and the accession number is B5TYU1.
TMPH-00117	Ara h 1, clone P17 Protein, Arachis hypogaea, Recombinant (His)	Arachis hypogaea	E. coli
	N/A. Ara h 1, clone P17 Protein, Arachis hypogaea, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 71.7 kDa and the accession number is P43237.
TMPY-06667	Ara h 9.0101 Protein, Arachis hypogaea, Recombinant	Arachis hypogaea	P. pastoris (Yeast)
	Ara h 9.0101 Protein, Arachis hypogaea, Recombinant is expressed in P. pastoris yeast expression system. The predicted molecular weight is 18.9 kDa.
TMPH-00119	Conglutin-7 Protein, Arachis hypogaea, Recombinant (His)	Arachis hypogaea	E. coli
	Weak inhibitor of trypsin. Conglutin-7 Protein, Arachis hypogaea, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 22.0 kDa and the accession number is Q6PSU...
TMPY-06151	Ara h 6 Protein, Arachis hypogaea, Recombinant (His)	Arachis hypogaea	P. pastoris (Yeast)
	Ara h 6 is a major peanut allergen showing similarity with Ara h 2 in many aspects. Ara h 6 is a major peanut allergen in children and adults. Ara h 6 has approximately the same seroprevalence as Ara h 2 and thus is con...