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Ketohypoglycin

Catalog No. T25572 CAS 5746-24-7

Synonyms: Methylenecyclopropylpyruvate

Ketohypoglycin has been utilized to study the inhibition of gluconeogenesis in isolated rat liver cells.

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Ketohypoglycin, CAS 5746-24-7

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25 mg	6-8 weeks	Inquiry

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Ketohypoglycin has been utilized to study the inhibition of gluconeogenesis in isolated rat liver cells.

Synonyms	Methylenecyclopropylpyruvate
Molecular Weight	140.14
Formula	C7H8O3
CAS No.	5746-24-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Kean EA, Pogson CI. Inhibition of gluconeogenesis in isolated rat liver cells by methylenecyclopropylpyruvate (ketohypoglycin). Biochem J. 1979 Sep 15;182(3):789-96. PubMed PMID: 518564; PubMed Central PMCID: PMC1161413. 2. Marusich JA, Grant KR, Blough BE, Wiley JL. Effects of synthetic cathinones contained in "bath salts" on motor behavior and a functional observational battery in mice. Neurotoxicology. 2012 Oct;33(5):1305-13. doi: 10.1016/j.neuro.2012.08.003. Epub 2012 Aug 23. PubMed PMID: 22922498; PubMed Central PMCID: PMC3475178. 3. Kler RS, Sherratt HS, Turnbull DM. The measurement of mitochondrial beta-oxidation by release of 3H2O from [9,10-3H]hexadecanoate: application to skeletal muscle and the use of inhibitors as models of metabolic disease. Biochem Med Metab Biol. 1992 Apr;47(2):145-56. PubMed PMID: 1515172. 4. Billington D, Sherratt HS. Hypoglycin and metabolically related inhibitors. Methods Enzymol. 1981;72:610-6. PubMed PMID: 7311858.

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Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ketohypoglycin 5746-24-7 Methylenecyclopropylpyruvate inhibitor inhibit

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