pathogenic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T40863	Bisdionin C		Antibacterial
	Bisdionin C is a potent inhibitor of GH18 chitinase with an IC50 of 0.2 μM for A. fumigatus ChiB1. Bisdionin C inhibits human macrophage chitotriosidase(HCHT, IC50 = 8.3 μM) and acidic mammalian chitinase (AMCase, IC50 =...		Antibacterial
T20237	Fenhexamid	Elevate,Teldor	Antifungal
	Fenhexamid (Elevate), a sterol biosynthesis inhibitor, shows antifungal activity against the plant pathogenic fungus. Fenhexamid is used for agriculture and is present in measurable amounts in fruits and vegetables.		Antifungal
TN2279	Totarol	(+)-Totarol	Antibacterial , Antifection
	Totarol ((+)-Totarol) shows antibacterial effects against several pathogenic Gram-positive bacteria, mycobacterium tuberculosis.		Antibacterial , Antifection
T6105	Phosphorylcholine chloride	phosphorylcholine,Phosphocholine chloride	Others
	Phosphorylcholine chloride, an antigenic component found on the surface of numerous commensal and pathogenic bacteria inhabiting the upper airway, is integral to bacterial cell surfaces.		Others
TP1309	Gastric mucin		Antibacterial , Antibiotic
	Gastric mucin is a large glycoprotein which is thought to play a major role in the protection of the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma.		Antibacterial , Antibiotic
T7897	PK150		Others , Antibacterial
	PK150 shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations.		Others , Antibacterial
T9508	MONOCAPRYLIN	Sefsol 318,Glyceryl monocaprylate	Antibacterial
	Monocaprylin (Sefsol 318) is a monoglyceride of caprylic acid with an excellent antibacterial activity. Monocaprylin inhibits a variety of foodborne pathogenic and spoilage microorganisms and has the potential for an alt...		Antibacterial
T9208	1,3,6,8-Tetrahydroxynaphthalene	T4HN,1,3,6,8-THN,naphthalene-1,3,6,8-tetrol	Others
	1,3,6,8-Tetrahydroxynaphthalene (T4HN) is a key precursor of 1,8-dihydroxynaphthalene-melanin, an important virulence factor in pathogenic fungi, where T4HN is believed to be the direct product of pentaketide synthases		Others
T15001	Corypalmine		Others , Antifungal
	Corypalmine is a kind of alkaloid from Coptis chinensis and purple chinensis, which has inhibitory effect on the germination of plant pathogenic spores and saprophytic fungi.		Others , Antifungal
T9231	Mbx2329		Antiviral
	MBX2329 is a specific inhibitor of HA-mediated viral entry that inhibits H1N1 virus strain high pathogenic avian influenza H5N1 virus strain.		Antiviral
T27617	Inz-1		P450
	Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human. Inz-1 reverses Fluconazole or other triazole antifungals’ resistance in the path...		P450
T39057	Rozanolixizumab	UCB7665	Others
	Rozanolixizumab (RYSTIGGO) is a high-affinity humanized immunoglobulin G4 monoclonal antibody targeting Fc receptors (FcRn) in human newborns for the study of pathogenic IgG in autoimmune and alloimmune diseases.		Others
T37069	Pyribencarb	ZINC43065336	Antifungal
	Pyribencarb (), a benzylcarbamate-type fungicide, exhibits broad-spectrum activity against various plant pathogenic fungi. Acting as a potent Qo inhibitor of cytochrome b, Pyribencarb demonstrates particular efficacy aga...		Antifungal
TN6993	Benzylideneacetone	Benzalacetone	Phospholipase , Endogenous Metabolite
	Benzylideneacetone, a monoterpene produced by the insect pathogenic bacterium Xenorhabdus nematophila, is a phospholipase A2 (PLA2) inhibitor with inhibitory effects on arachidonoid biosynthesis and enhances baculovirus ...		Phospholipase , Endogenous Metabolite
T74756	SDH-IN-2		Antifungal
	SDH-IN-2 is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 0.55 μg/mL.SDH-IN-2 possesses antifungal activity, with average EC50 values of 3.82-9.81 μg/mL for inhibition of plant pathogenic fungi.		Antifungal
T3S0057	Dihydrochelerythrine	12,13-Dihydrochelerythrine	Antifungal
	1. Dihydrochelerythrine (12,13-Dihydrochelerythrine) is nontoxic up to 5μM concentration. 2. Dihydrochelerythrine has antifungal activity against pathogenic plant fungi. 3. Dihydrochelerythrine has potential application ...		Antifungal
T5S0993	Kurarinone		BCL , Others , IκB/IKK , TNF , NF-κB , JAK , STAT
	Kurarinone, a flavanoid derived from shrub Sophora flavescens,Kurarinone exhibits anti-tumor, estrogenic, and anti-inflammatory activities, it also shows strong inhibitory effect on immune responses. Kurarinone may ameli...		BCL , Others , IκB/IKK , TNF , NF-κB , JAK , STAT
T10065L	2',3'-cGAMP sodium	2'-3'-cyclic GMP-AMP sodium	STING , cGAS
	2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium), a cGAMP synthase (cGAS) affecting cytoplasmic DNA production as a second messenger, is a transmembrane bridging protein that is a key component of the cellular innate imm...		STING , cGAS
T63059	CRK12-IN-1		Antibiotic
	CRK12-IN-1 is a potent CRK12 inhibitor.CRK12-IN-1 has insecticidal activity, with inhibitory effects on Trypanosoma brucei (T.b. brucei) and Trypanosoma congolense (T. congolense) with EC50s of 1.3 and 18 nM, respectivel...		Antibiotic
TP1120L	IRBP acetate(211426-18-5 free base)	Interphotoreceptor Retinoid Binding Protein Fragment IRBP	Others
	IRBP acetate(211426-18-5 free base) (Interphotoreceptor Retinoid Binding Protein Fragment IRBP) is a 20-residue peptide, which is a major pathogenic epitope. It exists in the first homologous repeat of interstitial visua...		Others