pancreatitis — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8198	Visnagin		Others
	Visnagin has acute hypotensive, anti-inflammatory, and neuroprotective effects, it protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase.		Others
T2391	Camostat mesylate	FOY-S980,FOY305,Camostat mesilate	Serine/threonin kinase , SARS-CoV , Sodium Channel
	Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.		Serine/threonin kinase , SARS-CoV , Sodium Channel
T34123	Pranazepide	FR120480,FK 480,FR-120480	cholecystokinin
	Pranazepide (FK 480) is a small molecule cholecystokinin receptor antagonist used to study digestive disorders and pancreatitis.		cholecystokinin
T5352	GLYCODEOXYCHOLIC ACID		Others , Endogenous Metabolite
	Glycodeoxycholic Acid is a bile acid that induces severe pancreatitis in rats. It can induce the apoptosis of SMMC-7721 cells.		Others , Endogenous Metabolite
T74140	β-D-Glucan		Others
	β-D-Glucan is a compound that targets tumor-associated macrophages with antitumor activity and modulates the immune response in necrotizing pancreatitis.		Others
T0372	Gabexate mesylate	FOY	Factor Xa , Serine Protease , Proteasome
	Gabexate mesylate (FOY) is a serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inh...		Factor Xa , Serine Protease , Proteasome
T9670L	Patamostat HCl	Patamostat HCl（114568-26-2 Free base）	Serine Protease , Protease
	Patamostat HCl is a highly potent and selective small molecule protease (protease) inhibitor that inhibits trypsin, fibrinolytic enzymes, and thrombin with IC50 values of 39 nM, 950 nM, and 1.9 μM, respectively.Patamosta...		Serine Protease , Protease
T67749	Fuzapladib	IS-741	Phospholipase
	Fuzapladib (IS-741) (IS-741) is a phospholipase A2 inhibitor that can inhibits the expression of Mac-1, a cell adhesion molecule. Fuzapladib blocks activation of adhesion molecules (integrin) expressed on the inflammator...		Phospholipase
T28248	Ono-3307 mesylate	Ono-3307,Ono3307,Ono 3307	Protease
	Ono-3307 mesylate is a protease inhibitor with inhibitory effects on a variety of proteases.Ono-3307 mesylate has significant protective effects against liver injury in rats and inhibits the deposition of radiofibrillar ...		Protease
T13662	Diarylalkane derivative 1		Others
	Diarylalkane derivative 1 is used for the research of pancreatitis.		Others
T25275	Crambene	NSC 321802,NSC-321802,NSC321802
	Crambene results in the induction of apoptosis by protects mice against acute pancreatitis via anti-inflammatory pathways.
T31569	DP-b99	DP-b-99,DP-BAPTA-99,DPb-99,DPBAPTA-99,DP-b 99
	DP-B 99 (DP-B 99, DP-BAPTA-99, DPB-99, DP-BAPTA-99) is a potential chelating agent for the treatment of acute pancreatitis.
T78376	Rimtoregtide
	Rimtoregtide, a polypeptide, markedly attenuates the elevations in blood amylase and lipase levels associated with acute pancreatitis, suggesting its potential utility in the research of pancreatitis and acute pancreatit...
T37771	Taurolithocholic Acid 3-sulfate (sodium salt)
	Taurolithocholic acid 3-sulfate (TLCA3S) is a metabolite of the conjugated bile acid taurolithocholic acid . TLCA3S has been used to study bile acid transport in cellular models and to induce pancreatitis in mouse models...
T33314	Methantheline Bromide	Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide
	Methantheline Bromide is a synthetic spasmolytic used to relieve cramps or spasms of the stomach, bowel, and bladder. It is also useful for intestinal or gastric ulcers (peptic ulcer disease), intestinal problems, pancre...
T10055	(Iso)-FK-480	CHEMBL333994	cholecystokinin
	(Iso)-FK-480 is a novel orally available cholecystokinin A (CCK-A) antagonist for investigational treatment of chronic pancreatitis.		cholecystokinin
T38521	Patamostat mesylate	E-3123 mesylate
	Patamostat mesylate (E-3123) is a highly potent protease inhibitor, displaying strong inhibitory activity against trypsin, plasmin, and thrombin, with IC 50 values of 39 nM, 950 nM, and 1.9 μM, respectively. This compoun...
T9670	Patamostat
	Patamostat (E-3123) is a potent protease inhibitor that effectively inhibits trypsin, plasmin, and thrombin, exhibiting IC50 values of 39 nM, 950 nM, and 1.9 µM, respectively. Research suggests that Patamostat might supp...
T36623	Antileukinate
	Antileukinate is a synthetic hexapeptide with an acetylated amino terminus and an amidated carboxyl terminus that inhibits the binding of CXC chemokines to the chemokine receptor CXCR2. It inhibits IL-8 binding to neutro...
T22506	3,4-DAA		NOS
	3,4-DAA has anti-inflammatory activity, ameliorates acute hepatic allograft injury, and alleviates severe acute pancreatitis by inhibiting intestinal barrier dysfunction and NF-κB activation.3,4-DAA inhibits EOC20 cell-i...		NOS