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Methantheline Bromide

Catalog No. T33314 CAS 53-46-3

Synonyms: Frenogastrico, Dixamone bromide, Banthine, Asabaine, Methanthelinium bromide

Methantheline Bromide is a synthetic spasmolytic used to relieve cramps or spasms of the stomach, bowel, and bladder. It is also useful for intestinal or gastric ulcers (peptic ulcer disease), intestinal problems, pancreatitis, gastritis, biliary dysmotility, pyloric or urinary problems.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Methantheline Bromide Chemical Structure

Methantheline Bromide, CAS 53-46-3

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Frenogastrico, Dixamone bromide, Banthine, Asabaine, Methanthelinium bromide
Molecular Weight	420.34
Formula	C21H26BrNO3
CAS No.	53-46-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Müller C, Berensmeier A, Hamm H, Dirschka T, Reich K, Fischer T, Rzany B. Efficacy and safety of methantheline bromide (Vagantin(®) ) in axillary and palmar hyperhidrosis: results from a multicenter, randomized, placebo-controlled trial. J Eur Acad Dermatol Venereol. 2013 Oct;27(10):1278-84. doi: 10.1111/j.1468-3083.2012.04708.x. Epub 2012 Sep 25. PubMed PMID: 23004926. 2. [Hyperhidrosis. Effective reduced sweating with methantheline bromide]. MMW Fortschr Med. 2012 May 31;154(10):68-9. German. PubMed PMID: 22803247. 3. Newburger J, Kotenbauder HB. The effect of ion-pair formation on the lethal dose of methantheline bromide. Life Sci. 1977 Feb 15;20(4):627-30. PubMed PMID: 14290. 4. NOGAMI H, AWAZU S, IWATSURU M. STUDIES ON DECOMPOSITION AND STABILIZATION OF DRUGS IN SOLUTION. XIV. STABILIZATION OF METHANTHELINE BROMIDE AND CHOLINE DERIVATIVES IN AQUEOUS SOLUTION BY SURFACE-ACTIVE AGENTS. Chem Pharm Bull (Tokyo). 1963 Oct;11:1251-5. PubMed PMID: 14075277.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Methantheline Bromide 53-46-3 Frenogastrico Dixamone bromide Banthine Dixamone Bromide Asabaine Methanthelinium Bromide Methanthelinium bromide inhibitor inhibit

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