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Ono-3307 mesylate

Catalog No. T28248   CAS 76472-29-2
Synonyms: Ono-3307, Ono3307, Ono 3307

Ono-3307 mesylate is a protease inhibitor with inhibitory effects on a variety of proteases.Ono-3307 mesylate has significant protective effects against liver injury in rats and inhibits the deposition of radiofibrillar proteins in the kidneys and lungs.PF-184298 is a protease inhibitor with potential antioxidant effects in plasma and adipose tissue.PF-184298 can be used in the study of pancreatitis.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Ono-3307 mesylate Chemical Structure
Ono-3307 mesylate, CAS 76472-29-2
Pack Size Availability Price/USD Quantity
1 mg In stock $ 293.00
5 mg In stock $ 722.00
10 mg In stock $ 987.00
25 mg In stock $ 1,520.00
50 mg 6-8 weeks $ 1,980.00
100 mg 6-8 weeks $ 2,500.00
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Purity: 98.16%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Ono-3307 mesylate is a protease inhibitor with inhibitory effects on a variety of proteases.Ono-3307 mesylate has significant protective effects against liver injury in rats and inhibits the deposition of radiofibrillar proteins in the kidneys and lungs.PF-184298 is a protease inhibitor with potential antioxidant effects in plasma and adipose tissue.PF-184298 can be used in the study of pancreatitis.
Synonyms Ono-3307, Ono3307, Ono 3307
Molecular Weight 430.46
Formula C15H18N4O7S2
CAS No. 76472-29-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Yoshikawa T, et al. Protective effects of ONO-3307, a new synthetic protease inhibitor against experimental disseminated intravascular coagulation in rats. Thromb Res. 1990 Oct 1;60(1):1-7. 2. Matsuoka S, et al. Inhibitory effects of ONO-3307 on various proteases and tissue thromboplastin in vitro and on experimental thrombosis in vivo. Jpn J Pharmacol. 1989 Dec;51(4):455-63. 3. Hirano T,et al. Impaired hepatic energy metabolism in rat acute pancreatitis: protective effects of prostaglandin E2 and synthetic protease inhibitor ONO 3307. J Surg Res. 1992 Sep;53(3):238-44. 4. Hirano T,et al. Protective effects of combined therapy with a protease inhibitor, ONO 3307, and a xanthine oxidase inhibitor, allopurinol on temporary ischaemic model of pancreatitis in rats. Nihon Geka Hokan. 1992 May 1;61(3):224-33.

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Keywords

Ono-3307 mesylate 76472-29-2 Proteases/Proteasome Protease Ono-3307 Ono3307 Ono 3307 mesylate Ono-3307 Mesylate Ono3307 mesylate Ono 3307 inhibitor inhibit

 

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