myocytes — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TMS2171	(±)-Naringenin	Salipurpol,Naringenine,Naringenin	Potassium Channel
	(±)-Naringenin (Naringenine) is a natural product. It displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes.		Potassium Channel
T15286	Flindokalner	BMS-204352	Potassium Channel
	Flindokalner (BMS-204352) is a potassium channel modulator and a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. Flindokalner is a large conductance calcium-activated K channel (BKca) p...		Potassium Channel
T3S0208	Hederagenin 28-O-beta-D-glucopyranosyl ester	Hederagenin-28-beta-D-glucopyranoside	Others
	Hederagenin-28-beta-D-glucopyranoside, a triterpene saponin isolated from Ilex cornuta, protects cardiac myocytes against H2O2-induced damage.		Others
T7578	REVERSE T3	3,3',5'-triiodo-L-thyronine	Thyroid hormone receptor(THR)
	Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.		Thyroid hormone receptor(THR)
T3574	Sematilide hydrochloride	CK-1752A,CK-1752,Sematilide HCl	Potassium Channel
	Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the ...		Potassium Channel
T12853	SBI-477		Others
	SBI-477 is a chemical probe stimulated insulin signaling by deactivating the transcription factor MondoA. SBI-477 coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal...		Others
T7044	Norepinephrine	Levophed,Levonoradrenaline,Aktamin,Nor-Epirenan,Levonor,Arterenol	MMP , Endogenous Metabolite , Adrenergic Receptor , Autophagy
	Norepinephrine (Levophed) can stimulate apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway. It can up-regulate the expression of vascular endothelial growth factor, matrix metalloprotei...
T30249	AZD 7009	AZD-7009,AZD7009	Sodium Channel
	AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM. AZD 7009 inhibited late sodium current in isolated rabbit atrial and ventricular myocytes, an...		Sodium Channel
T35834L	(Sar¹)-Angiotensin II acetate		RAAS
	(Sar¹)-Angiotensin II acetate, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. It binds to brain membrane-rich particles, with a Kd of 2.7 nM. It can stimulate protein synthesis and cell...		RAAS
TP1937L1	RFRP-1 (human) acetate(311309-25-8 free base)		Neuropeptide Y Receptor
	RFRP-1 (human) acetate is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduc...		Neuropeptide Y Receptor
TP1913L1	BA 1 acetate(183241-31-8 free base)		Bombesin Receptor
	BA 1 acetate is a potent bombesin receptor agonist (IC50 values are 0.26, 1.55 and 2.52 nM for BB1, BB2 and BB3 respectively). Enhances glucose transport in obese and diabetic primary myocytes. Also stimulates NCI-H1299 ...		Bombesin Receptor
T2530	Levosimendan	OR1259,OR1855	Potassium Channel , PDE , Carbonic Anhydrase , Autophagy
	Levosimendan (OR1259) is a calcium sensitizer used in the management of acutely decompensated congestive heart failure. It increases the sensitivity of the heart to calcium, thus increasing cardiac contractility without ...		Potassium Channel , PDE , Carbonic Anhydrase , Autophagy
T68123	Oxodipine		Calcium Channel
	Oxodipine, a dihydropyridine-type calcium antagonist , inhibited KCl-induced aortic contraction in rabbits and reduced cardiac force in less potent rat ventricular test-paper contractions. In rat cultured neonatal ventri...		Calcium Channel
T15487	HMR 1556		Others
	HMR 1556 is a chromanol derivative and is an IKs blocker (IC50s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively).		Others
T28779	SIM-6080
	SIM-6080 is a calcium channel antagonist. SIM-6080 inhibits the proliferation of rat aortic myocytes.
T75947	RFRP-1(human) TFA
	RFRP-1(human) TFA, an endogenous NPFF receptor agonist, exhibits potent activity with EC50 values of 0.0011 nM for NPFF2 and 29 nM for NPFF1. It significantly diminishes the contractile function of isolated rat and rabbi...
TP1937	RFRP-1(human)	RFRP-1 (human)
	Potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume...
TP1913	BA 1
	Potent bombesin receptor agonist (IC50 values are 0.26, 1.55 and 2.52 nM for BB1, BB2 and BB3 respectively). Enhances glucose transport in obese and diabetic primary myocytes. Also stimulates NCI-H1299 lung cancer cell p...
T21927	A 61603 hydrobromide
	A-61603 is a selective agonist of α 1A -adrenergic receptor [1]. A-61603 increases the frequency of spontaneous Ca 2+ transients in rat ventricular myocytes in vitro [2].
T35628	AN-7
	α-Lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form. It is an essential cofactor for decarboxylation reactions of the citric acid cycle and acts as a general antioxidant. AN-7...