12
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8158 | Tilianin | Others | |
Tilianin is a flavonoid glycoside of Dragocephalum moldavicum L. | |||
T3S0289 | Araloside X | Calcium Channel | |
Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane perox... | |||
T5S1632 | Barlerin | 8-O-Acetylshanzhiside methyl ester,ND01 | VEGFR , TNF , NF-κB , Akt , Caspase |
Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and its protective effect on oxygen-glucose deprivation-induced injury might be due to the suppression of intracellular Ca2+ e... | |||
T2S0500 | Ilexsaponin A | Ilexsaponin A1 | Others |
1. Ilexsaponin A (Ilexsaponin A1) shows protective effects on ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway. | |||
T3920 | Pseudoginsenoside F11 | Ginsenoside A1 | Others , Endogenous Metabolite |
Pseudoginsenoside F11 (Ginsenoside A1) is a component of Panax quinquefolium (American ginseng) which main pharmacological activities are positive inotropic effect on isolated heart function, good therapeutic effect on m... | |||
T9180 | LUF6096 | CF-602 | Adenosine Receptor |
LUF6096 (CF-602) is a potent allosteric enhancer of the adenosine A3 receptor, exhibiting the capability to enhance agonist binding allosterically while demonstrating low orthosteric affinity across adenosine receptors. ... | |||
T2973 | Astragaloside IV | AST-IV,AS-IV | MMP , ERK , Estrogen/progestogen Receptor , JNK |
Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cel... | |||
T4S2326 | Cornuside | 7-Galloylsecologanol,7-O-Galloylsecologanol,Comuside | ERK , p38 MAPK , NF-κB , JNK |
1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardi... | |||
T4S0280 | Eleutheroside D | ||
Eleutheroside has protective effect to myocardial ischemic-reperfusion injury(IRI) in isolated rats. | |||
T72281 | Caspase-9 Inhibitor III | Ac-LEHD-cmk | |
Caspase-9 Inhibitor III (Ac-LEHD-cmk), a caspase-9 inhibitor, exhibits protective effects against ischemia-reperfusion-induced myocardial injury. | |||
T68878 | L-2286 | ||
L-2286 is a novel PARP inhibitor. L-2286 exerted significant protective effect against ischemia-reperfusion-induced myocardial injury in both experimental models. More importantly, L-2286 facilitated the ischemia-reperfu... | |||
TN3914 | Echinatine | ATPase , IL Receptor , TNF | |
Echinatin exerts a protective effect against ischemia/reperfusion (I/R)-induced myocardial injury on hearts, this effect may be attributed to the antioxidant and anti-inflammatory activities of this compound. Echinatin c... |