Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Boc-gly-PEG3-endo-BCN is a PEG-based PROTAC linker and a cleavable 2-unit PEG ADC linker, utilized in the synthesis of PROTACs[1] and antibody-drug conjugates (ADCs)[2], respectively.
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Description | Boc-gly-PEG3-endo-BCN is a PEG-based PROTAC linker and a cleavable 2-unit PEG ADC linker, utilized in the synthesis of PROTACs[1] and antibody-drug conjugates (ADCs)[2], respectively. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2]. |
Molecular Weight | 553.69 |
Formula | C28H47N3O8 |
CAS No. | 2110444-63-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Boc-gly-PEG3-endo-BCN 2110444-63-6 Others Boc-gly-PEG-3-endo-BCN Boc gly PEG3 endo BCN BocglyPEG3endoBCN inhibitor inhibit