20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8961 | GW280264X | Carbamic acid | MMP |
GW280264X (Carbamic acid) is an inhibitor of ADAM17 . | |||
T5361 | T-26c | MMP | |
T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor (IC50: 6.75 pM). | |||
T16966 | S 3304 | MMP | |
S 3304 is a novel matrix metalloproteinases inhibitor which is specific for MMP-2 and MMP-9. | |||
T14978 | CL-82198 | MMP | |
CL-82198, a selective MMP-13 inhibitor, serves as a pharmacological intervention to halt the progression of osteoarthritis (OA). Its mechanism of action involves binding to the S1’ pocket of MMP-13, ensuring its selectiv... | |||
T4783 | JNJ0966 | MMP | |
JNJ0966 is a highly selective MMP-9 zymogen inhibitor (IC50: 440 nM). | |||
T3414 | Morroniside | Apoptosis , MMP , Pyroptosis | |
Morroniside would act as a regulator of hepatic inflammatory reactions and lipid metabolism in db/db mice. It exhibits protective effects against diabetic renal damage and human umbilical vein endothelial cells, by inhib... | |||
T2993 | Cordycepin | 3'-Deoxyadenosine | MMP , TNF , Antibacterial , Antibiotic , Autophagy |
Cordycepin (3'-Deoxyadenosine) is a purine nucleoside antimetabolite and antibiotic isolated from the fungus Cordyceps militaris with potential antineoplastic activity. | |||
T16124 | MMP13-IN-3 | MMP | |
MMP13-IN-3 is >1000 selective over other MMPs. MMP13-IN-3 is an effective, selective, and orally active MMP-13 inhibitor (IC50=1 nM) for the potential treatment of osteoarthritis. | |||
T5416 | T-5224 | MMP | |
T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription factors. | |||
T6011 | Batimastat | BB94 | MMP |
Batimastat (BB94) (BB-94) is an effective, broad-spectrum matrix metalloprotease (MMP) inhibitor. Batimastat induces extracellular matrix degradation and inhibits angiogenesis, tumor growth and invasion, and metastasis. | |||
T5983 | O-Phenanthroline | 1,10-Phenanthroline | MMP , Others |
o-Phenanthroline (1,10-Phenanthroline) , a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells.o-Phenanthroline protects mammalian cells from hydrogen peroxide-induced gene m... | |||
T4115 | Auraptene | 7-geranyloxycoumarin | MMP , BACE |
Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits le... | |||
T1891 | NSC 405020 | MMP | |
NSC 405020 is a noncatalytic inhibitor of MT1-MMP. | |||
TN1879 | Lucideric acid A | Lucidenic acid A | MMP , p38 MAPK , JNK |
Lucideric acid A (Lucidenic acid A) is a modulator of JNK and p38 and enhances LPS-induced immune responses in monocytic THP-1 cells possibly via the modulation of p38 and JNK/MAPKs activation. | |||
T8310 | MMP-9-IN-1 | MMP | |
MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9). | |||
T2967 | Stigmasterol | Stigmasterin,beta-Stigmasterol | MMP , Endogenous Metabolite |
Stigmasterol (Stigmasterin) is found in the fats and oils of soybean, calabar bean and rape seed, as well as several other vegetables, legumes, nuts, seeds, and unpasteurized milk. Stigmasterol has been focused on the ch... | |||
T7522 | GI254023X | GI 254023X | MMP , Immunology/Inflammation related |
GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM) with 100-fold selectivity for the α-secretase ADAM10 over ADAM17 (TACE). GI254023X can remarkably inhibit the proliferation and induce the apoptosis... | |||
T3860 | Isoliquiritin apioside | MMP , p38 MAPK , NF-κB | |
Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced activation of MAPK and NF-κB. Isoliquiritin apioside auppresse... | |||
T4282 | S-methyl-KE-298 | MMP , Drug Metabolite | |
S-methyl-KE-298 is the second main metabolite in plasma,is a methyl conjugate of deacetyl-KE-298.KE-298 inhibits matrix metalloproteinase (MMP-1) production from rheumatoid arthritis (RA) synovial cells. | |||
T2743 | Ilomastat | Galardin,GM6001 | MMP |
Ilomastat (GM6001) (GM6001, Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor. |