maturation — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T25049	Allethrin		BCL , Caspase
	Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.		BCL , Caspase
T7992	4-Hydroxyflavanone		NO Synthase
	4-Hydroxyflavanone is a natural product, shows full vasorelaxing effects		NO Synthase
T5782	Bevirimat	YK FH312,MPC-4326,PA-457	HIV Protease
	Bevirimat (PA-457) is a first-in-class inhibitor of HIV-1 maturation, blocking the cleavage of the Gag capsid (CA) precursor, CA-SPI, to mature CA protein during virion maturation.		HIV Protease
TP1806L	BCMA72-80 acetate(2293841-58-2 free base)		Others
	BCMA72-80 acetate is a HLA-A2 specific B cell maturation antigen (BCMA) peptide. It is used to study multiple myeloma and tumors, which expresses B cell maturation antigen.		Others
T15436	GSK2838232		HIV Protease
	GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates,GSK2838232 is novel human immune virus (HIV) maturation inhibitor.		HIV Protease
T26854	BMS641	BMS-641,BMS-209641,BMS 641	Retinoid Receptor
	BMS641 (BMS-209641) is a selective and potent RARβ agonist.BMS641 has a high affinity for RARβ and synergistically activates RARβ and RARgamma to induce cellular maturation into specialized neuronal subtypes.		Retinoid Receptor
T9773	Thioquinapiperifil dihydrochloride	KF-31327	PDE
	Thioquinapiperifil dihydrochloride is a phosphodiesterase (PDE-5) inhibitor (IC50: 0.074 nM) that is potent, selective and non-competitive for investigational maturation.		PDE
T26955	Cavosonstat	N91115,N 91115,N-91115	GSNOR , CFTR
	Cavosonstat (N91115) is an orally active S-nitrosoglutathione reductase (GSNOR) inhibitor that promotes cystic fibrosis transmembrane conductance regulator (CFTR) maturation and plasma membrane stabilization.Cavosonstat ...		GSNOR , CFTR
T2595	Lumacaftor	VX-809,VRT 826809	CFTR , Autophagy
	Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. It enhances F508del-CFTR protein maturation in FRT cells (EC50: 100 nM).		CFTR , Autophagy
T67887	BDCRB
	BDCRB inhibits herpesvirus DNA maturation. BDCRB causes the HCMV terminase to skip the normal cleavage site and to continue to package DNA until a second cleavage site is encountered 30 kb further along the concatemer.
T9975	GPR183	3-(3,4-difluorophenyl)-N-[3-fluoro-5-(morpholin-4-yl)phenyl]propanamide	Others
	GPR183 (3-(3,4-difluorophenyl)-N-[3-fluoro-5-(morpholin-4-yl)phenyl]propanamide) is a chemotactic receptor known for its role in the maturation of B cells, and the endogenous ligand is the oxysterol 7α,25-dihydroxycholes...		Others
T21992	Vacuolin-1		PI3K , Autophagy
	Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane. It acts by inhibiting release of lysosomal content.vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits ...		PI3K , Autophagy
T2162	Maribavir	BW1263W94,GW257406X,Benzimidavir,1263W94	Others , HCV Protease
	Maribavir (GW257406X) is an orally available benzimidazole riboside compound with activity against cytomegalovirus (CMV). Maribavir is a selective ATP competitor of the viral UL97 kinase, which is involved in viral nucle...		Others , HCV Protease
TP1293	Jagged-1 (188-204) TFA(219127-21-6 free base)	Jagged-1 (188-204) TFA	Gamma-secretase
	Jagged-1 (188-204) TFA(219127-21-6 free base) is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing sub...		Gamma-secretase
T5S2357	Acetylcorynoline	(+)-Corynoline Acetate,O-Acetylcorynoline	Antifungal
	1. Acetylcorynoline (O-Acetylcorynoline) has antifungal、anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. 3...		Antifungal
T2563	Acetyl-L-carnitine hydrochloride	Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride	Others , Endogenous Metabolite
	Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) is a nutritional supplement composed of the hydrochloride salt form of the acetylated form of the endogenously produced L-carnitine, with potential neur...		Others , Endogenous Metabolite
T3226	Paritaprevir	ABT-450,Veruprevir	HCV Protease
	Paritaprevir (ABT-450) is an orally bioavailable, synthetic acylsulfonamide inhibitor of the hepatitis C virus (HCV) protease complex comprised of non-structural protein 3 and 4A (NS3/NS4A), with potential activity again...		HCV Protease
T26933	BzDANP	Benzo DANP,Benzo-DANP,BenzoDANP
	BzDANP is a modulator of pre-miR-29a maturation by Dicer.
T69986	BMS-955176 HCl
	GSK-3532795 is a second generation inhibitor of hiv-1 maturation, exhibiting a broader spectrum of antiviral effect in vitro and in clinical studies than the prototypical maturation inhibitor bevirimat
T27737	KNI-272	NSC-651714,Kynostatin-272,Kynostatin272,KNI272,Kynostatin 272
	Kynostatin-272 is a HIV protease inhibitor. KNI-272 blocked the maturation of viral particles.