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GPR183

Catalog No. T9975 CAS 1241280-25-0

Synonyms: 3-(3,4-difluorophenyl)-N-[3-fluoro-5-(morpholin-4-yl)phenyl]propanamide

GPR183 (3-(3,4-difluorophenyl)-N-[3-fluoro-5-(morpholin-4-yl)phenyl]propanamide) is a chemotactic receptor known for its role in the maturation of B cells, and the endogenous ligand is the oxysterol 7α,25-dihydroxycholesterol (7α,25-OHC). GPR183 can be used in research on inflammatory bowel disease (IBD).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

GPR183, CAS 1241280-25-0

Pack Size	Availability	Price/USD
1 mg	In stock	$ 97.00
5 mg	In stock	$ 247.00
10 mg	In stock	$ 397.00
25 mg	In stock	$ 663.00
50 mg	In stock	$ 945.00
100 mg	In stock	$ 1,280.00
1 mL * 10 mM (in DMSO)	In stock	$ 272.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	3-(3,4-difluorophenyl)-N-[3-fluoro-5-(morpholin-4-yl)phenyl]propanamide
Molecular Weight	364.36
Formula	C19H19F3N2O2
CAS No.	1241280-25-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (137.22 mM)

References and Literature

1. Misselwitz B, et al. The oxysterol receptor GPR183 in inflammatory bowel diseases. Br J Pharmacol. 2021 Aug;178(16):3140-3156. 2. Braden K, et al. GPR183-Oxysterol Axis in Spinal Cord Contributes to Neuropathic Pain. J Pharmacol Exp Ther. 2020 Nov;375(2):367-375.

Related compound libraries

This product is contained In the following compound libraries：

Immunology/Inflammation Compound Library Bioactive Compound Library Bioactive Compounds Library Max

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

GPR183 1241280-25-0 Others GPR183 antagonist-1 SAE-14 3-(3,4-difluorophenyl)-N-[3-fluoro-5-(morpholin-4-yl)phenyl]propanamide inhibit GPR-183 SAE 14 SAE14 HL-60 Inhibitor GPR 183 GPR183 antagonist SAE-14 EBI2/GPR183 inhibitor

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