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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T19833 | 5-Fluoroorotic acid | DNA/RNA Synthesis , Antifungal | |
5-Fluoroorotic acid is an inhibitor of thymidylate synthase. 5-Fluoroorotic is a selective agent in yeast molecular genetics.5-Fluoroorotic possesses a well-expressed anticandidal effect close to that of 5-fluorocytosine... | |||
T72013 | Epigenetic Multiple Ligand | ||
Epigenetic Multiple Ligand is a cell-permeable inhibitor of substrate processing by several chromatin-associated enzymes, including SIRT1/2, H3/SET7, H3/p300/CBP, H4/RmtA, PABP1/CARM1, and H4/PRMT1. It acts by inducing e... | |||
T82458 | Epigenetic factor-IN-1 | Sirtuin | |
Epigenetic factor-IN-1 (40569Z) is an epigenetic factor inhibitor that exhibits potent binding affinity for SIRT7. It is utilized in the study of liver cancer [1]. | |||
T63806 | CFTR corrector 8 | CFTR | |
CFTR corrector 8 is a highly effective modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). This compound is specifically designed for utilization in research related to cystic fibrosis, a genetic... | |||
T68110 | Moxnidazole | ||
Moxnidazole, a 5-nitroimidazole, is mutagenic in microbial assays and in Drosophila, inducing genetic alterations in mouse somatic cells. | |||
T9733 | PAL-4 | 1H-1,2,4-Triazol-5-amine, 3-[[(4-chlorophenyl)methyl]thio]-1-[(2,3-dihydro-5-benzofuranyl)sulfonyl]- | Others |
PAL-4 stimulates the activity of LYPLAL1, a poorly characterized serine hydrolase with complex genetic links to human metabolic traits. | |||
T10531 | BGB-102 | JNJ-26483327 | EGFR , VEGFR , FLT , Src |
BGB-102 (JNJ-26483327) is a kinase inhibitor targeting FLT3 and YES1 and an antagonist targeting EGFR and VEGFR3, which may be useful in the study of macular degeneration and diseases associated with genetic disorders an... | |||
T6468 | D-glutamine | Mitophagy , Ferroptosis , Endogenous Metabolite , GluR , Autophagy | |
D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code. | |||
T4762 | L-Pipecolic acid | L-Homoproline,H-HoPro-OH | Endogenous Metabolite |
L-Pipecolic acid (L-Homoproline) is a breakdown product of lysine, accumulates in body fluids of infants with generalized genetic peroxisomal disorders, such as Zellweger syndrome, neonatal adrenoleukodystrophy. | |||
T4877 | L-Homocystine | Endogenous Metabolite | |
Homocystine is the double-bonded form of homocysteine, but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Increasing evidence supports a role for an ele... | |||
T73400L | PG-11047 2HCl | PG-11047 2HCl(949933-50-0 Free base),CGC-11047 2HCl | Apoptosis |
PG-11047 2HCl is an apoptosis-stimulating agent used in the treatment of genitourinary disorders, immune system disorders, genetic disorders and malformations, ocular disorders, and disorders of the blood and lymphatic s... | |||
T4781 | N-Acetyl-L-phenylalanine | N-Ac-Phenylalanine | Others , Endogenous Metabolite |
N-Acetyl-L-phenylalanine (N-Ac-Phenylalanine) is an essential amino acid produced for medical, feed, and nutritional applications. It appears in large amount in urine of patients with phenylketonuria which is a human gen... | |||
T5219 | L-Alloisoleucine | L-allo-Isoleucine,(3R)-LS-Isoleucine,L(+)-Alloisoleucine | Others , Endogenous Metabolite |
L-Alloisoleucine (L-allo-Isoleucine) is a branched chain amino acid and is a stereoisomer of L-isoleucine. It is a common constituent of human plasma (albeit at low levels). L-alloisoleucine is produced as a byproduct of... | |||
T5267 | N-Acetyl-L-glutamic acid | Ac-L-Glu-OH,N-Acetylglutamic acid | Others , Endogenous Metabolite |
N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) (NAcGlu) is an acetylated amino acid. NAcGlu is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetyl glutamate synthase (NAGS). NAcGlu activates carbamoyl phospha... | |||
T4971 | 5'-DEOXYADENOSINE | 5′-dAdo | Endogenous Metabolite |
5'-Deoxyadenosine (5′-dAdo) is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material, which has long be... | |||
T4944 | Nervonic acid | cis-15-Tetracosenoic acid,Selacholeic acid | Endogenous Metabolite |
Nervonic acid (Selacholeic acid) is a long chain unsaturated fatty acid that is enriched in sphingomyelin. It consists of choline, sphingosine, phosphoric acid, and fatty acid. Nervonic acid may enhance the brain functio... | |||
T4827 | Trimethylammonium chloride | Trimethylamine hydrochloride | Others , Endogenous Metabolite |
Trimethylammonium chloride (Trimethylamine hydrochloride) is a product of decomposition of plants and animals. It is the substance mainly responsible for the fishy odor often associated with fouling fish, bacterial vagin... | |||
T28511 | Reglitazar | JTT-501,JTT501,PNU-182716,PNU182716,PNU-716 | |
Reglitazar is a PPARɑ agonist and PPARγ agonist. Reglitazar rapidly stimulates glucose disposal rates by enhancing insulin signal transduction in skeletal muscle. Reglitazar improves insulin resistance in genetic and non... | |||
T16912 | Sortin1 | Others | |
Sortin1, a chemical genetic-hit compound, specifically induces mislocalization of both soluble and membrane-associated vacuolar markers in plants and yeast. | |||
T31601 | Eclanamine maleate | U-48753E,U48,753E,U-48,753E,U48753E,U 48,753E | |
Eclanamine was discovered to be slightly mutagenic in the AS52 assay, and a potential agent which was subjected to a battery of short-term assays for genetic activity. |