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Search Results for " fibrogenesis "

8

Compounds

Cat No. Product Name Synonyms Targets
T0462 Cilostazol OPC 21,OPC 13013 PDE , Autophagy
Cilostazol (OPC 21) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of cilostazol is as a Phosphodiesterase 3 Inhibitor.
T0518 Methacycline hydrochloride Rondomycin,Methacycline HCl ribosome , Antibacterial , Antibiotic
Methacycline hydrochloride (Rondomycin) is a broad-spectrum semisynthetic antibiotic related to TETRACYCLINE but excreted more slowly and maintaining effective blood levels for a more extended period.
T8505 SC-236 Sc 236 Apoptosis , COX , PPAR
SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).
T38737L SDKPDMAEIEKFDKSK acetate SDKPDMAEIEKFDKSK acetate(1339864-27-5 free base) Others
SDKPDMAEIEKFDKSK acetate is a thymosin β4 derivative. Thymosin β4 inhibits PDGF-BB-induced fibrogenesis, proliferation and migration of HSC by blocking Akt phosphorylation.
T11807 L002 Others , Histone Acetyltransferase , STAT
L002, a potent, cell-permeable, reversible, and specific acetyltransferase p300 (KAT3B) inhibitor with an IC50 of 1.98 μM, directly binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain. By ...
T41231 GP 1a Cannabinoid Receptor , PERK , Arrestin
GP 1a is a potent agonist of cannabinoid receptor 2 (CB2) (EC50=7.1), as shown in cAMP, GTPγS and β-arrestin recruitment assays. GP 1a is approximately 30-fold more selective for CB2 receptors than CB1 receptors and incr...
T67961 Safironil Others
safironil is a novel antifibrotic compound and a competitive inhibitor of collagen synthesis. safironil inhibited in vitro experiments on fibroblast activation monitored by collagen I mRNA or smooth muscle alpha-actin le...
T5S0106 Peimisine Ebeiensine RAAS , AChR
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe...
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