exposure — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2086	ELN-441958	ELN 441958	Bradykinin Receptor
	ELN-441958 is a potent, neutral antagonist of B1 receptor, inhibits the binding of the B1 agonist ligand [3H]DAKD to IMR-90 cells with Ki of 0.26 nM. ELN-441958(ELN 441958) is highly selective for B1 over B2 receptors.		Bradykinin Receptor
T21995	XAP044		GluR
	XAP044 is a mGlu7-selective antagonist which inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice with a half-maximal blockade at 88 nm[1].		GluR
T15430	GSK2256294A	GSK 2256294	Others , Epoxide Hydrolase
	GSK2256294A (GSK 2256294) is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively.		Others , Epoxide Hydrolase
T1812	KX1-004	KX1 004,KX1004	Src
	KX1-004, a potential protective drug for NIHL, is an effective small molecule inhibitor of Src-PTK.		Src
TN7118	Methylhippuric acid	Methyl hippurate
	Methylhippuric acid (Methyl hippurate) is a xylene exposure biomarker in human urine.
T20039	7-Methyladenine	NSC7857,NSC-7857,NSC 7857	Others
	7-Methyladenine (NSC-7857) can be used as a marker of exposure to exogenous and carcinogenic methylating agents.		Others
T4931	Dihydroxyfumaric acid hydrate		Others , Endogenous Metabolite
	Dihydroxyfumaric acid is a known generator of superoxide anions and by hydroxyl free radicals. Dihydroxyfumarate exposure can cause insulin inhibitory effects. It can spontaneously convert to hydroxypyruvate or to oxalog...		Others , Endogenous Metabolite
T3106	C-DIM12		Apoptosis , Others
	C-DIM12 induced expression of Nurr1-regulated genes. C-DIM12 increased expression of transfected human Nurr1, induced Nurr1 protein expression in primary dopaminergic neurons and enhanced neuronal survival from exposure ...		Apoptosis , Others
T35501	5,6-trans-Vitamin D3	5,6-trans-Colecalciferol,5,6-trans-Cholecalciferol,Cholecalciferol EP Impurity A	Vitamin
	5,6-trans-Vitamin D3（5,6-trans-Cholecalciferol） is an isoform of Vitamin D3, which is converted from Vitamin D3 on the skin surface after light exposure.		Vitamin
T5S1550	Cinnamyl alcohol	Cinnamic Alcohol,Styryl Carbinol	PPAR
	Cinnamyl alcohol (Styryl Carbinol) readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay.		PPAR
T19082	1-Hydroxypyrene	1-Pyrenol,Pyren-1-ol	Endogenous Metabolite
	1-Hydroxypyrene (1-Pyrenol), a biomarker of exposure to polycyclic aromatic hydrocarbons, is analyzed in urine samples.		Endogenous Metabolite
T0976	Propoxur	Aprocarb,Propoxure,Baygon	AChR , Antifungal
	Propoxur (Propoxure) is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propoxur by ingestion leads to cholinesterase inhibition of red b...		AChR , Antifungal
T21404	Fluticasone furoate	Veramyst,Allermist,Avamys,Fluticasone furoate	Glucocorticoid Receptor
	Fluticasone furoate (Avamys) is a synthetic trifluorinated corticosteroid derived from fluticasone with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflammatory, anti-asthmatic activity, and low systemic exposure...		Glucocorticoid Receptor
T5718	L-(+)-Abrine	L-N-Methyltryptophan,N-α-Methyl-L-tryptophan,L-ABRINE	Others
	L-(+)-Abrine (L-N-Methyltryptophan) is a toxic protein found in the jequirity seed.,can be used as a biomarker for abrin exposure.		Others
T8547	DCBA		Drug Metabolite
	DCBA, an endogenous metabolite of the insect repellent N-N-diethyl-meta-toluamide (DEET), is utilized to evaluate DEET exposure through its concentration levels in urine.		Drug Metabolite
T36478	BI-6901		CCR
	BI-6901 is a CCR10 antagonist. In a mouse model of DNFB exposure hypersensitivity, BI 6901 displays its anti-inflammatory response in a dose-dependent manner.		CCR
T3746	Dimethyl phthalate	Solvanom,Avolin,Fermine	Others
	Dimethyl phthalate (Fermine) has many uses, including in solid rocket propellants, plastics, and insect repellants. Acute (short-term) exposure to dimethyl phthalate, via inhalation in humans and animals, results in irri...		Others
TQ0039	(±)-Zanubrutinib	(±)-BGB-3111	BTK
	(±)-Zanubrutinib ((±)-BGB-3111) is a potent and orally available Bruton's tyrosine kinase (Btk) inhibitor that demonstrates superior oral bioavailability, achieving higher exposure and more complete target inhibi.		BTK
T2S0633	Raspberry ketone	Oxyphenalon,Rasketone,Aloenin,4-(4-Hydroxyphenyl)-2-butanone,p-Hydroxybenzyl acetone,Frambinone	PPAR
	1. Raspberry ketone (p-Hydroxybenzyl acetone) is cytotoxic to melanocytes through the binding of RK-derived quinones to thiol proteins and the pro-oxidant activity of the RK-oligomer, the exposure of human skin to RK can...		PPAR
T17315	(±)-CPSI-1306	cpsi-1306,2-(3-(2,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)-1-morpholinoethan-1-one	Others
	(±)-CPSI-1306 (2-(3-(2,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)-1-morpholinoethan-1-one) is a macrophage migration inhibitory factor (MIF) antagonist and can be used in studies about non-insulin-dependent diabetes mel...		Others