cardioprotective — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3809	Liriope muscari baily saponins C		Others
	Liriope muscari baily saponins C has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of TF and IL-6.		Others
T21640	Talinolol		Adrenergic Receptor
	(±)-Talinolol is a selective β1 adrenoceptor antagonist well known for its cardioprotective and antihypertensive activity.		Adrenergic Receptor
T1940	BTB06584		RAAS , ATPase
	BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. BTB06584 is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising drug target against Mycobacterium tuberculosis (MTB).		RAAS , ATPase
T24109	GSK329	GSK 329,GSK-329	Others
	GSK329 is an effective and selective inhibitor of TNNI3 Interacting Kinase (TNNI3K). GSK329 exhibits positive cardioprotective outcomes in the model of ischemia/reperfusion cardiac injury.		Others
T21919	UCF 101		Apoptosis
	UCF 101 is a specific inhibitor of HtrA2 and reduces apoptosis in PC12 cells.		Apoptosis
T9714	Atpenin A5		Potassium Channel
	Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM). Atpenin A5 is also an effective mKATP channel agonist and cardioprotective agent[1].		Potassium Channel
T0075	Nicorandil	SG-75	Potassium Channel
	Nicorandil (SG-75)(Ikorel) acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system. It undertakes this through two methods. Firstly, by activating potassium channels, and secondly b...		Potassium Channel
TN2144	Resveratroloside		P450 , NO Synthase
	Resveratroloside has cardioprotective effect, it exhibits α±-glucosidase inhibitory activity, it also can inhibit hydroxylation of testosterone by CYP3A4.		P450 , NO Synthase
T2763	Panaxadiol	20(R)-Panaxadiol	Others , HIF/HIF Prolyl-Hydroxylase
	Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.		Others , HIF/HIF Prolyl-Hydroxylase
T12478L	Pinacidil	S 1230,P 1134,S-1230,P-1134,P1134	Potassium Channel
	Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure and peripheral resistance and producing fluid retention.		Potassium Channel
T19335	Danegaptide Hydrochloride	GAP-134 (Hydrochloride),ZP 1609 Hydrochloride	Gap Junction Protein
	Danegaptide Hydrochloride (GAP-134 (Hydrochloride)) (GAP-134 Hydrochloride) is a selective modifier of the gap junction protein.		Gap Junction Protein
TN1982	Neoglycyrol		Others
	Neoglycyrol shows some cardioprotective effects .		Others
T3885	ROSIRIDIN	6'-O-Deacetylrosiridoside C,(-)-Rosiridin	Others , Monoamine Oxidase
	Rosiridin (6'-O-Deacetylrosiridoside C) has cardioprotective activity.		Others , Monoamine Oxidase
T25859	Necrostatin-7	Necrostatin 7,Necrostatin7,Nec 7,Nec-7,Nec7	Apoptosis
	Necrostatin-7 (Necrostatin 7) is an inhibitor of necrotic apoptosis with cardioprotective effects, inhibits RANK-NFATc1 signaling, and attenuates macrophage differentiation into osteoblasts.		Apoptosis
T37807	JTV 519 fumarate
	Ryanodine receptor (RyR) inhibitor; stabilizes RyR2 in a closed conformation. Exhibits antiarrhythmic and cardioprotective properties in vivo. Hunt et al (2007) K201 (JTV519) suppresses spontaneous Ca2+ release and [3H]r...
T10874	CP-060		Calcium Channel
	CP-060 is a potent Ca2+ antagonist and inhibits Ca2+ overload with antioxidant and cardioprotective activities.		Calcium Channel
T8493	Ingliforib	GPi 296,CP 368296	Phosphorylase
	Ingliforib (CP 368296) is a novel glycogen phosphorylase inhibitor,has antihyperglycemic and cardioprotective properties.		Phosphorylase
T6454	CORM-3	CORM3	Others , NF-κB , NOD-like Receptor (NLR)
	CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.		Others , NF-κB , NOD-like Receptor (NLR)
T68077	Furnidipine
	Furnidipine significantly reduced AoD and AF and had antiarrhythmic and cardioprotective effects at low doses in a rat model.
T5S0833	Astragaloside III		Antioxidant
	Astragaloside III has cardioprotective effects as well as causing improvement in cognitive function. It can be used in the prevention of cardio-cerebral vascular diseases. It also is antioxidant.		Antioxidant