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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN1754 | Hypaconine | Others | |
Hypaconine is a C19-diterpenoid alkaloid isolated from Aconitum and Delphinium spp. It exhibits strong cardiac activity. | |||
TN2054 | Periplocymarin | Calcium Channel | |
Periplocymarin is a cardiac glycoside with anticancer potential isolated from Periploca sepium and Periploca graeca. | |||
T0267 | Zonisamide | AD 810,CI 912 | Calcium Channel , Sodium Channel , Carbonic Anhydrase |
Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydrase although this is not one of the main mechanisms... | |||
T15052 | Dapansutrile | NOD-like Receptor (NLR) , NOD | |
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity. | |||
T2052 | KY02111 | Wnt/beta-catenin | |
KY02111 facilitates differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, maybe affect downstream of GSK3β and APC. | |||
T23351 | Shz 1 | Others | |
induces phenotypic differentiation | |||
T9258 | Aficamten | Others | |
Aficamten is a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy. | |||
T22341 | GSK-114 | Others | |
GSK-114, a selective inhibitor of TNNI3 Interacting Kinase (TNNI3K) with IC50 of 25 nM, shows significant bias for TNNI3K over B-Raf with IC50 of 1000 nM, exceptional broad spectrum kinase selectivity and adequate oral e... | |||
T8786 | VUT-MK142 | Others | |
VUT-MK142 is a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes,which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair. | |||
T1787 | Levobupivacaine | Sodium Channel | |
Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZ... | |||
TN1039 | Tamarixetin | 4'-O-Methyl Quercetin | Endogenous Metabolite , Immunology/Inflammation related |
Tamarixetin (4'-O-Methyl Quercetin) (4'-O-Methyl Quercetin) is a natural flavonoid derivative of quercetin, with anti-inflammatory and anti-oxidative effects. Tamarixetin protects against cardiac hypertrophy. | |||
T11807 | L002 | Others , Histone Acetyltransferase , STAT | |
L002, a potent, cell-permeable, reversible, and specific acetyltransferase p300 (KAT3B) inhibitor with an IC50 of 1.98 μM, directly binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain. By ... | |||
T8391 | Cesium chloride | CsCl | Potassium Channel |
Cesium chloride (CsCl) is considered to be the most toxic of the alkali chlorides, inhibiting fungal growth. | |||
T24109 | GSK329 | GSK 329,GSK-329 | Others |
GSK329 is an effective and selective inhibitor of TNNI3 Interacting Kinase (TNNI3K). GSK329 exhibits positive cardioprotective outcomes in the model of ischemia/reperfusion cardiac injury. | |||
T16686 | Pyr10 | TRP/TRPV Channel | |
Pyr10 is a pyrazole derivative and a selective TRP cation 3 inhibitor. Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1)/Orai1 channels. Pyr10 inhibits... | |||
T3S0081 | Oxypeucedanin | (+-)-Oxypeucedanin,Oxypeucadanin | Potassium Channel |
1. Oxypeucedanin ((+-)-Oxypeucedanin) has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. 2. Oxypeucedanin is a kind of open-channel blocke... | |||
T3144 | BML-284 | Wnt agonist 1 | Wnt/beta-catenin |
BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator. | |||
T9232 | Mitochondrial fusion promoter M1 | Mitochondrial Metabolism | |
Mitochondrial fusion promoter M1, a modulator of mitochondrial dynamics, enhances mitochondrial function and cellular respiration, and has shown efficacy in reducing brain and cardiac damage in rats suffering from cardia... | |||
T6086 | Clopamide | Brinaldix,Adurix,Aquex | Sodium Channel |
Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity. | |||
T3408 | Syringin | Lilacin,Syringoside,eleutheroside-b,Methoxyconiferine | NOS , Autophagy |
Syringin (eleutheroside-b) is a compound with antitumor, antiproliferative, immunomodulatory and platelet aggregation inhibiting effects. |