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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14667 | BLT-1 | Others , HCV Protease | |
BLT-1 is a scavenger receptor BI (SR-BI)inhibitor. | |||
T5326 | Sugammadex sodium | Org25969,Sugammadex (sodium) | Others |
Sugammadex sodium (Org25969) , a synthetic derivative of γ-cyclodextrin, is a steroid-based neuromuscular blocker reversing agent. | |||
T5275 | 2,5-Furandicarboxylic acid | Dehydromucic Acid,2,5-Dicarboxyfuran | Others , Endogenous Metabolite |
2,5-Furandicarboxylic acid (Dehydromucic Acid) is a normal urinary metabolite in humans. 2,5-Furandicarboxylic acid is also a microbial metabolite, a product of the oxidation of hydroxymethylfurfural (HMF) by the enzyme ... | |||
T6134 | IEM 1754 2HBr | IEM 1754 dihydrobromide | GluR |
IEM 1754 2HBr (IEM 1754 dihydrobromide) is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM. | |||
T0370 | Pheniramine maleate | Daneral,Inhiston,Trimetose | 5-HT Receptor , Histamine Receptor |
Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived re... | |||
T11063 | DMT1 blocker 1 | Others | |
DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with IC50 of 0.64 μM, which is expected to block the absorption of iron by intestinal cells in vivo. | |||
T11064 | DMT1 blocker 2 | Others | |
DMT1 blocker 2, compound 12f, is a direct inhibitor of divalent metal transporter 1 (DMT1) with an IC50 hydrogen peroxide value of 0.83, which is expected to block iron uptake by intestinal epithelial cells in vivo. | |||
T8741 | MitoBloCK-10 | 3-fluoro-N'-[(E)-(5-nitrothiophen-2-yl)m | Others |
MitoBloCK-10 (3-fluoro-N'-[(E)-(5-nitrothiophen-2-yl)m) inhibits Tim44 binding to the precursor and to Hsp70.MitoBloCK-10 is the first small molecule modulator to attenuate protein-associated motor (PAM) complex activity... | |||
T72170 | NaV1.2/1.6 channel blocker-1 | Sodium Channel | |
NaV1.2/1.6 channel blocker-1 is a potent NaV1.2/1.6 channel blocker with inhibitory effects on rNaV1.6 and hNaV1.2.NaV1.2 channel blocker-1 can be used in the study of generalised epilepsy and movement disorders. | |||
T60143 | MitoBloCK-6 | Apoptosis | |
MitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC 50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 with IC 50 of 1.4 μM. MitoBloCK-6 can induce apoptosis via cytochrome c release in human embryo... | |||
T26078 | Rhodblock 6 | Rhodblock6,Rhodblock-6 | ROCK |
Rhodblock 6 is a Rho kinase (ROCK) inhibitor that inhibits the localization of phosphorylated MRLC (Myosin Regulatory Light Chain) and acts by specifically inhibiting Rho kinase activity. | |||
T12504 | (+)-KCC2 blocker 1 | Potassium Channel | |
(+)-KCC2 blocker 1 is a selective blocker of KCC2 (IC50 = 0.4 μM). | |||
T10690 | Cav 2.2 blocker 1 | Calcium Channel | |
Cav 2.2 blocker 1 is an N-type calcium channel (Cav 2.2; IC50: 1 nM) blocker for the treatment of pain. | |||
T8782 | MitoBloCK-11 (MB-11) | Others | |
MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, con... | |||
T12153 | N-type calcium channel blocker-1 | Calcium Channel | |
N-type calcium channel blocker-1 is an orally active analgesic agent,shows high affinity to functionally block N-type calcium channels. | |||
T26077 | Rhodblock 3 | ||
Rhodblock 3 is a potent small molecule Rho pathway inhibitor. | |||
T28132 | NaV1.7 Blocker-801 | ||
NaV1.7 Blocker-801 is a potent NaV1.7 blocker. | |||
T80930 | TRPV2-selective blocker 1 | ||
TRPV2-selective blocker 1 (compound IV2-1) is a selective inhibitor of the TRPV2 channel, exhibiting an IC50 value of 6.3 μM. It specifically targets the TRPV2 channel without impacting related TRPV1, TRPV3, or TRPV4 cha... | |||
T62586 | Cav 2.2/3.2 blocker 1 | ||
Cav 2.2/3.2 blocker 1 (Compound 9e) is a neuronal calcium channel blocker that acts on Cav2.2 (IC50: 1.22 μM) and Cav3.2 (IC50: 80 μM). Can penetrate the central nervous system. | |||
T69387 | NMO-IgG blocker A-01 | ||
NMO-IgG blocker A-01 is a idiotype-specific blocker of neuromyelitis opticaimmunoglobulin g (nmo-igg) binding to aquaporin-4 (aqp4) |