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Rhodblock 6

Catalog No. T26078 CAS 886625-06-5

Synonyms: Rhodblock6, Rhodblock-6

Rhodblock 6 is a Rho kinase (ROCK) inhibitor that inhibits the localization of phosphorylated MRLC (Myosin Regulatory Light Chain) and acts by specifically inhibiting Rho kinase activity.

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Rhodblock 6, CAS 886625-06-5

Pack Size	Availability	Price/USD
1 mg	In stock	$ 106.00
5 mg	In stock	$ 249.00
10 mg	In stock	$ 368.00
25 mg	In stock	$ 618.00
50 mg	In stock	$ 883.00
100 mg	In stock	$ 1,190.00
500 mg	In stock	$ 2,420.00

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Purity: 98.27%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Rhodblock 6 is a Rho kinase (ROCK) inhibitor that inhibits the localization of phosphorylated MRLC (Myosin Regulatory Light Chain) and acts by specifically inhibiting Rho kinase activity.
In vitro	Rhodblock 6 (1-30 μM) strongly inhibits ROCK activity in a dose-dependent manner. Rhodblock 6 (100 μM; 20 h) can cause the rupture of stress fibers in human HeLa cells.[1]

Synonyms	Rhodblock6, Rhodblock-6
Molecular Weight	215.25
Formula	C12H13N3O
CAS No.	886625-06-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Castoreno AB, et al. Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis. Nat Chem Biol. 2010;6(6):457-463.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library TGF-beta/Smad Compound Library Bioactive Compound Library Kinase Inhibitor Library Anti-Cancer Compound Library Bioactive Compounds Library Max

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CCG-222740 Thiazovivin WAY-656935 GSK269962A Y-9738 YAP/TAZ inhibitor-1 Chroman 1 CCG-232964

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Rhodblock 6 886625-06-5 Cell Cycle/Checkpoint Cytoskeletal Signaling Stem Cells ROCK Rhodblock6 Rhodblock-6 inhibitor inhibit

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