anesthesia — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7045	Clonidine	Nexiclon,Catapres,Kapvay	Adrenergic Receptor
	Clonidine (Kapvay) is a centrally active alpha-adrenergic agonist used predominantly as an antihypertensive agent, usually in combination with other agents. Despite wide-scale use for many years, clonidine has not been l...		Adrenergic Receptor
T5326	Sugammadex sodium	Org25969,Sugammadex (sodium)	Others
	Sugammadex sodium (Org25969) , a synthetic derivative of γ-cyclodextrin, is a steroid-based neuromuscular blocker reversing agent.		Others
T0862	Diphenidol hydrochloride	Diphenidol HCl,Difenidol hydrochloride	Sodium Channel , AChR
	Diphenidol hydrochloride (Difenidol hydrochloride), a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug.		Sodium Channel , AChR
T0364L	Dibucaine hydrochloride	Cinchocaine HCl,Dibucaine HCl,Cinchocaine hydrochloride	Sodium Channel , AChR
	Dibucaine hydrochloride (Cinchocaine hydrochloride), a long-acting local amide anestheticsis, is usually used for surface anesthesia.		Sodium Channel , AChR
T0364	Dibucaine	Cinchocaine	CaMK , Sodium Channel , AChR
	Dibucaine (Cinchocaine), a local anesthetic of the amide type, is now usually used for surface anesthesia.		CaMK , Sodium Channel , AChR
T33272	Mefenidil	McN-2378,McN 2378	Others
	Mefenidil (McN-2378), a selective cerebral vasodilator, was shown to increase CBF in healthy brains without stimulating O2 uptake in a dog anesthesia model.		Others
T0012	Cinchonine	LA40221,(8R,9S)-Cinchonine	Apoptosis , P-gp , Parasite
	Cinchonine (LA40221), a local anesthetic of the amide type, now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local narcotics and its parenteral use is restricted to spi...		Apoptosis , P-gp , Parasite
T13142L	Theodrenaline hydrochloride	Theodrenaline hydrochloride(13460-98-5 Free base)	SARS-CoV
	Theodrenaline hydrochloride is an inhibitor targeting SARS-CoV-2 for the study of hypotension induced by spinal anesthesia.		SARS-CoV
T5734	(+)-BORNEOL	d-Borneol	GABA Receptor
	(+)-BORNEOL (d-Borneol) is a natural bicyclic monoterpene used for analgesia and anesthesia in traditional Chinese medicine; enhances GABA receptor activity with an EC50 of 248 μM.		GABA Receptor
Fr16605	Lupinine		AChR , AChE
	Lupinine is an alkaloid capable of counteracting ethanol anesthesia. Lupinine is an AChE and BChE inhibitor and potential CD69 activator found in species of Loranthus, Calia, and Lupinus. It may also inhibit heparin.		AChR , AChE
T2524	Dexmedetomidine		Adrenergic Receptor
	Dexmedetomidine is a Central alpha-2 Adrenergic Agonist. The mechanism of action of dexmedetomidine is as an Adrenergic alpha2-Agonist. The physiologic effect of dexmedetomidine is by means of General Anesthesia.		Adrenergic Receptor
T0029	Procaine	Duracaine,Spinocaine,Novocaine,Vitamin H3	Histone Demethylase , DNA/RNA Synthesis , Sodium Channel
	Procaine (Vitamin H3) is a local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block.		Histone Demethylase , DNA/RNA Synthesis , Sodium Channel
T1198	Tetracaine hydrochloride	Amethocaine hydrochloride,Amethocalne HCl,Tetracaine HCl	Calcium Channel , Sodium Channel
	Tetracaine hydrochloride (Amethocalne HCl) (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. It is primarily used as an antipruritic and topically in ophthalmology, and it has been use...		Calcium Channel , Sodium Channel
T19658	Enflurane	NSC115944,Ethrane,NSC-115944,Efrane,NSC 115944	Others
	Enflurane (Efrane), a volatile anaesthetic, is a potent inhibitor of high conductance Ca2+-activated K+ channels of Chara australis. Enflurane is an internal standard in monitoring halogenated volatile anaesthetics by he...		Others
T1787	Levobupivacaine		Sodium Channel
	Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZ...		Sodium Channel
T31914	Gantacurium chloride	GW 280430A,AV4430A,AV 4430A,GW280430,GW 280430,GW-0430
	Gantacurium chloride is a benzylisoquinoline alkaloid, which may be used as an adjuvant in anesthesia.
T31296	Decamethonium chloride	Decamethylenebis(trimethylammonium chloride),Decamethonium dichloride
	Decamethonium is a depolarizing muscle relaxant or neuromuscular blocking agent,[1] and is used in anesthesia to induce paralysis.
T28259	Org-21465	Org21465,Org 21465
	Org-21465, a gamma-aminobutyric acid (GABA) receptor agonist, is used potentially for the use of anesthesia.
T28591	Ro 48-6791	Ro-486791,Ro 486791,Ro-48-6791,Ro486791,Ro48-6791
	Ro 48-6791, a GABA receptor agonist, is used potentially for anesthesia.
T34753	Suxamethonium bromide	L.T. 1,370 I.S.,Brevidil M
	Suxamethonium bromide can be used to cause short-term paralysis as part of general anesthesia.