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Enflurane

Catalog No. T19658 CAS 13838-16-9

Synonyms: NSC115944, Ethrane, NSC-115944, Efrane, NSC 115944

Enflurane (Efrane), a volatile anaesthetic, is a potent inhibitor of high conductance Ca2+-activated K+ channels of Chara australis. Enflurane is an internal standard in monitoring halogenated volatile anaesthetics by headspace gas chromatography-mass spectrometry. It allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate.

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Enflurane, CAS 13838-16-9

Pack Size	Availability	Price/USD
50 mg	In stock	$ 30.00
100 mg	In stock	$ 41.00
500 mg	In stock	$ 97.00

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Purity: 99.64%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	NSC115944, Ethrane, NSC-115944, Efrane, NSC 115944
Molecular Weight	184.49
Formula	C3H2ClF5O
CAS No.	13838-16-9

Storage

store at low temperature

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/ml (298.12 mM)

References and Literature

1. Andrade LA, Silla JM, Stephens SL, Marat K, da Cunha EF, Ramalho TC, van Wijngaarden J, Freitas MP. Conformational Exploration of Enflurane in Solution and in a Biological Environment. J Phys Chem A. 2015 Oct 29;119(43):10735-42. doi: 10.1021/acs.jpca.5b08087. Epub 2015 Oct 19. PubMed PMID: 26461140. 2. Liu H, Weng H. Up-regulation of Alzheimer's disease-associated proteins may cause enflurane anesthesia induced cognitive decline in aged rats. Neurol Sci. 2014 Feb;35(2):185-9. doi: 10.1007/s10072-013-1474-x. Epub 2013 Aug 11. PubMed PMID: 23934553. 3. Hung O. From the Journal archives: Early clinical evaluation of enflurane: the cost of progress. Can J Anaesth. 2014 Mar;61(3):269-72. doi: 10.1007/s12630-013-0091-8. Epub 2013 Dec 7. PubMed PMID: 24318728. 4. Zierkiewicz W, Czarnik-Matusewicz B, Michalska D. Blue shifts and unusual intensity changes in the infrared spectra of the enflurane···acetone complexes: spectroscopic and theoretical studies. J Phys Chem A. 2011 Oct 20;115(41):11362-8. doi: 10.1021/jp205081r. Epub 2011 Sep 13. PubMed PMID: 21913646.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library FDA-Approved & Pharmacopeia Drug Library Bioactive Compounds Library Max Bioactive Compound Library FDA-Approved Drug Library NO PAINS Compound Library Approved Drug Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Enflurane 13838-16-9 Others Inhibitor Potassium Channel mass standard internal NSC115944 anaesthetic volatile Ethrane NSC-115944 spectrometry inhibit Efrane KcsA NSC 115944 inhibitor

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