adrenoceptors — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T14127	Adenosine A1 receptor activator T62		Adenosine Receptor
	Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve...		Adenosine Receptor
T23283	2-Methoxyidazoxan monohydrochloride	RX 821002 hydrochloride	Adrenergic Receptor
	L-Albizziin (2-Methoxyidazoxan monohydrochloride) is a highly potent selective antagonist of the alpha 2r adrenergic receptor, with little or no antagonistic effect on imidazoline. It has a significantly higher affinity ...		Adrenergic Receptor
T22904	L-745870 trihydrochloride	L-745,870 trihydrochloride	Dopamine Receptor , Sigma receptor , 5-HT Receptor , Adrenergic Receptor
	L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist.
T22052	BU 226 hydrochloride		Imidazoline Receptor
	BU 226 hydrochloride demonstrates affinity for imidazoline (I) receptors, in particular the I2 binding site with a Ki of 1.4 nM. BU 226 hydrochloride showed low (microM) affinity for alpha 2-adrenoceptors.		Imidazoline Receptor
T28895	T-0509	T 0509,T0509	Adrenergic Receptor
	T-0509 is a selective beta 1 receptor agonist that increases inotropy in canine ventricular muscle and selectively down-regulates rat cardiac beta 1-adrenoceptors.		Adrenergic Receptor
T22316	Doxazosin	UK 33274	Adrenergic Receptor
	Doxazosin (UK 33274) is a long-lasting inhibitor of α1-adrenoceptors that is widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms.		Adrenergic Receptor
T10000	(±)-Tazifylline		Histamine Receptor
	(±)-Tazifylline is a selective and long-acting antagonist of histamine H1 receptor. Tazifylline shows much lower affinity for H2 receptors, α- and β-adrenoceptors, 5-hydroxytryptamine and muscarinic receptor subtypes.		Histamine Receptor
T3232	Higenamine hydrochloride	Higenamine HCl,Demethylcoclaurine hydrochloride,norcoclaurine HCl,(+-)-Demethylcoclaurine hydrochloride,Higenamine Hydrochloride	Adrenergic Receptor
	Higenamine hydrochloride (norcoclaurine HCl) has been demonstrated to be a β2 adrenoreceptor agonist. Adrenergic receptors, or adrenoceptors, belong to the class of G protein–coupled receptors, and are the most prominent...		Adrenergic Receptor
T3S1729	Dihydrolycorine		Others
	1. Dihydrolycorine-HCL(DL) shows hypotensive effects, it can block alpha 1-adrenoceptors. 2. Dihydrolycorine is an inhibitors of protein synthesis in eukarytic cells, it halts protein synthesis in eukaryotic cells by inh...		Others
T13804	OPC-28326		Adrenergic Receptor
	OPC-28326 is a specific an α2-adrenergic receptor antagonist and acts as a peripheral vasodilator. OPC-28326 inhibits α2A-, α2B- and α2C-adrenoceptors with Ki of 2040, 285, and 55 nM, respectively.		Adrenergic Receptor
T4S0998	Trifolirhizin		TNF , Tyrosinase
	Trifolirhizin exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, and therefore, are candidates as skin-whitening agents.Trifolirhizin possesses potential anti-inflammatory and anti-cancer ...		TNF , Tyrosinase
T11277	FG 7142	ZK 39106,LSU-65	GABA Receptor
	FG 7142 (LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cereb...		GABA Receptor
T4978	Sarpogrelate hydrochloride	MCI-9042	5-HT Receptor
	Sarpogrelate hydrochloride (MCI-9042) , a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD. Target: 5-HT2 Recepter Sarpogrelate is a drug which acts as an antagonist at ...		5-HT Receptor
T13376	YS-49		RAAS , Akt , PI3K , Adrenergic Receptor
	YS-49 is an activator of PI3K/Akt (a downstream target of RhoA).		RAAS , Akt , PI3K , Adrenergic Receptor
T23878	CH-38083	CH38083
	CH-38083 is a selective and effective alpha-2 adrenoceptors antagonist.
T71447	Perbufylline
	Perbufylline is a bronchodilator. It is N-methylated xanthine derivative. Perbufylline acts as a competitive antagonist at 5-HT2 and alpha1-adrenoceptors, with at least 100-fold less activity at alpha2-adrenoceptors.
T11763	Ko-3290		Others
	Ko-3290 is a cardioselective antagonist of β-adrenoceptors known for its antilipolytic effects in animals.		Others
T26784	BFE-61	BFE 61
	BFE-61 is a partial agonist of the beta-adrenoceptors.
T24462	Mezilamine
	Mezilamine is an antagonist of dopamine. It also blocks presynaptic but stimulating postsynaptic alpha-adrenoceptors.
T28172	Niguldipine hydrochloride	BY-935,Niguldipine HCl,B-85935,B-8509-035,B-859-35
	Niguldipine is a calcium channel antagonist. Niguldipine shows high affinity to Ca2+ channels and to a subtype of alpha 1-adrenoceptors.