Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve-injury pain[1][2][3].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 148.00 | |
5 mg | In stock | $ 322.00 | |
10 mg | In stock | $ 478.00 | |
25 mg | In stock | $ 772.00 | |
50 mg | In stock | $ 1,050.00 | |
100 mg | In stock | $ 1,420.00 | |
500 mg | In stock | $ 2,830.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 492.00 |
Description | Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve-injury pain[1][2][3]. |
In vivo | Adenosine A1 receptor activator T62 (0.3-3 μg; intrathecal administration; male SpragueDawley rats) treatment produces a dose-dependent antihypersensitivity effect. However it has no effect on ambulation or activity level[1]. |
Animal Research | Intrathecal T62 of Male SpragueDawley rats (250 g) after paw incision surgery with the dose of 0.3 μg, 0.5 μg, 1 μg, and 3 μg, produced a dose-dependent antihypersensitivity effect, with no effect on ambulation or activity level. The ED40 (95% confidence interval) for T62 was 0.77 (0.63-0.91) microg. |
Molecular Weight | 291.8 |
Formula | C15H14ClNOS |
CAS No. | 40312-34-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 75 mg/ml (257.03 mM)
You can also refer to dose conversion for different animals. More
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Adenosine A1 receptor activator T62 40312-34-3 GPCR/G Protein Neuroscience Adenosine Receptor allosteric Inhibitor P1 receptor adenosine hypersensitivity α2-adrenoceptors antihypersensitivity intrathecal Enhancer neuropathic Adenosine A-1 receptor activator T62 inhibit inhibitor