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Higenamine hydrochloride

Catalog No. T3232 CAS 11041-94-4

Synonyms: Higenamine HCl, Demethylcoclaurine hydrochloride, norcoclaurine HCl, (+-)-Demethylcoclaurine hydrochloride, Higenamine Hydrochloride

Higenamine hydrochloride (norcoclaurine HCl) has been demonstrated to be a β2 adrenoreceptor agonist. Adrenergic receptors, or adrenoceptors, belong to the class of G protein–coupled receptors, and are the most prominent receptors in the adipose membrane, besides also being expressed in skeletal muscle tissue.

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Higenamine hydrochloride Chemical Structure

Higenamine hydrochloride, CAS 11041-94-4

Pack Size	Availability	Price/USD	Quantity
100 mg	In stock	$ 42.00
1 mL * 10 mM (in DMSO)	In stock	$ 46.00

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Purity: 98.75%

Purity: 98.25%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Higenamine hydrochloride (norcoclaurine HCl) has been demonstrated to be a β2 adrenoreceptor agonist. Adrenergic receptors, or adrenoceptors, belong to the class of G protein–coupled receptors, and are the most prominent receptors in the adipose membrane, besides also being expressed in skeletal muscle tissue.
Source	Natural Products > Ranunculaceae > Aconitum

Synonyms	Higenamine HCl, Demethylcoclaurine hydrochloride, norcoclaurine HCl, (+-)-Demethylcoclaurine hydrochloride, Higenamine Hydrochloride
Molecular Weight	307.772
Formula	C16H18ClNO3
CAS No.	11041-94-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL(178.7 mM)

References and Literature

1. Tsukiyama M, et al. Beta2-adrenoceptor-mediated tracheal relaxation induced by higenamine from Nandina domestica Thunberg. Planta Med. 2009 Oct;75(13):1393-9.

Citations

1. Zhang H, Liang B, Sang X, et al.Discovery of Potential Inhibitors of SARS-CoV-2 Main Protease by a Transfer Learning Method.Viruses.2023, 15(4): 891.

Related compound libraries

This product is contained In the following compound libraries：

Membrane Protein-targeted Compound Library Anti-Cancer Drug Library Anti-Cancer Approved Drug Library Anti-Neurodegenerative Disease Compound Library Traditional Chinese Medicine Monomer Library Anti-Cancer Clinical Compound Library Drug Repurposing Compound Library GPCR Compound Library Bioactive Compounds Library Max Natural Product Library

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Related compounds with same targets

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Higenamine hydrochloride 11041-94-4 GPCR/G Protein Neuroscience Adrenergic Receptor Inhibitor Norcoclaurine Higenamine Higenamine HCl Demethylcoclaurine hydrochloride Beta Receptor inhibit norcoclaurine HCl (+-)-Demethylcoclaurine hydrochloride (+-)-Demethylcoclaurine Hydrochloride Higenamine Hydrochloride Higenamine Hydrochloride Demethylcoclaurine Hydrochloride inhibitor

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