administration — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7824	Eberconazole Nitrate	Ebernet	Antifungal
	Eberconazole Nitrate (Ebernet) is an azole antifungal agent and broad-spectrum imidazole derivative.		Antifungal
T22976	MFZ 10-7		Others , GluR
	MFZ 10-7 is anegative allosteric modulator of the mGluR5.		Others , GluR
T8959	OS-3-106		Dopamine Receptor
	OS-3-106 is a novel arylamide phenylpiperazines, as partial agonists at the D3R in the adenylyl cyclase inhibition assay.		Dopamine Receptor
T15799	LY2940094	LY-2940094	Opioid Receptor
	LY2940094 (LY-2940094) decreases ethanol self-administration in animal models. LY2940094 is an effective, selective, and orally available nociceptin receptor antagonist with high affinity (Ki=0.105 nM) and antagonist pot...		Opioid Receptor
T39161	Ro60-0175	Ro60-0175	5-HT Receptor
	Ro60-0175 a selective agonist for both the 5-hydroxytryptamine 2B (5-HT2B) and 5-hydroxytryptamine 2C (5-HT2C)serotonin receptor subtypes, commonly used as fumarate salt. It has a role as a 5-hydroxytryptamine 2B recept...		5-HT Receptor
T6322	Copanlisib	BAY 80-6946	Apoptosis , PI3K
	Copanlisib (BAY 80-6946) is a phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. Copanlisib inhibits the activation of the PI3K signaling pathway, which may result in inhibition of tumor c...		Apoptosis , PI3K
T14998	Copanlisib dihydrochloride	BAY 80-6946 dihydrochloride	Apoptosis , PI3K , mTOR
	Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is an ATP-competitive pan-class I PI3K inhibitor (IC50s: 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ). Copanlisib dihydrochloride has super...		Apoptosis , PI3K , mTOR
T1459	Cisatracurium besylate	51W89	Adrenergic Receptor , AChR , Autophagy
	Cisatracurium besylate (51W89) is a nondepolarizing skeletal muscle relaxant for intravenous administration.		Adrenergic Receptor , AChR , Autophagy
T21983L	PKI 14-22 amide, myristoylated Acetate	PKI 14-22 amide, myristoylated Acetate(201422-03-9 Free base)	PKA
	PKI 14-22 amide, myristoylated Acetate inhibit cAMP-dependent protein kinase (PKA) and blocks hyperalgesia produced by spinal administration of 8-bromo-cAMP.		PKA
T28396	PGP-4008	PGP 4008,PGP4008	P-gp
	PGP-4008 is a selective and potent P-glycoprotein (Pgp) inhibitor that inhibits tumor growth by co-administration with Doxorubicin.		P-gp
T5467	SAR125844	SAR125884	Apoptosis , c-Met/HGFR
	SAR125844, a potent and highly selective inhibitor of the MET receptor tyrosine kinase (RTK), for intravenous administration. (IC50 value of 4.2 nmol/L)		Apoptosis , c-Met/HGFR
T10124	Antiulcer Agent 1		Others
	Antiulcer Agent 1 is a 2-(3,4-dimethoxyphenyl)ethylamine derivative for oral administration.		Others
T5S2245	Alisol C 23-acetate	Alisol C monoacetate	Others
	Alisol C 23-acetate (Alisol C monoacetate) is a natural product isolated from Alisma orientale, can significantly and strongly inhibit DTH response after oral administration,has antibacterial activity.		Others
TN2023	8-Oxoepiberberine	Oxyepiberberine	Others
	8-Oxoepiberberine (Oxyepiberberine) is an alkaloid metabolite in the plasma after oral administration of Zuojin formula. Zuojin formula is a traditional chinese medicine used to treat gastrointestinal disease.		Others
T2322	Fimasartan	BR-A-657,Kanarb	Apoptosis , RAAS
	Fimasartan (BR-A-657) is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Concurrent administration of fimasartan with diuretic hydrochlorothiazide has show...		Apoptosis , RAAS
T69467	Azacosterol	IMD760,Diazasterol	Others
	Azacosterol (Diazasterol) is a DHCR24 inhibitor.Azacosterol undergoes a series of reactions in cortical neurons following oral or intraperitoneal administration.		Others
T79909	AEF0117		Cannabinoid Receptor
	AEF0117, a signaling-specific inhibitor of cannabinoid receptor 1 (CB1-SSi), inhibits cannabinoid self-administration and behavioral disorders associated with THC, and can be used to study cannabis withdrawal.		Cannabinoid Receptor
T71012	Nemazoline Free Base
	Nemazoline Free Base is a nasal decongestant. It has alpha 1-agonist/alpha 2-antagonist activity and was more effective and long-acting than oxymetazoline on canine nasal mucosa, in-vitro and in-vivo. Upon intranasal adm...
T9422	Fosciclopirox	CPX-POM	Gamma-secretase
	Fosciclopirox (CPX-POM), the phosphoryloxymethyl ester of CPX (Ciclopirox Prodrug, CPX-POM), selectively delivers the active metabolite, CPX, to the entire urinary tract following parenteral administration.		Gamma-secretase
T1551	Tegaserod maleate	HTF-919,SDZ-HTF-919	5-HT Receptor
	Tegaserod maleate (SDZ-HTF-919) is a 5-HT4 agonist manufactured by Novartis and used for the management of irritable bowel syndrome and constipation. Its use was the only drug approved by the United States Food and Drug ...		5-HT Receptor