acid-sensitive — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4316	ML365		Potassium Channel
	ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).		Potassium Channel
T1781	GW9508	GW 9508	GPR , Potassium Channel
	GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.		GPR , Potassium Channel
T20881	2-Iodobenzoic acid	o-Iodobenzoic acid,Kyselina o-jodbenzoova,2Iodobenzoic acid	Others
	2-Iodobenzoic acid (o-Iodobenzoic acid) is the impact-sensitive intermediate in the synthesis of the Dess-Martin periodinane.		Others
T0613	3-Hydroxyisovaleric acid	Beta-Hydroxyisovaleric acid	Others , Endogenous Metabolite
	3-Hydroxyisovaleric acid (Beta-Hydroxyisovaleric acid) is an endogenous metabolite excreted in the urine and can serve as an early and sensitive indicator of biotin deficiency.		Others , Endogenous Metabolite
T11579	HSL-IN-3	HSL inhibitor 3,Ethyl 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzoate	Others
	HSL-IN-3 (HSL inhibitor 3) is a boronic acid derivative that is an inhibitor of hormone-sensitive lipase(HSL).		Others
T3929	Kaurenoic acid	Kauren-19-Oic Acid,kaurenoate,kaur-16-en-18-oic acid	Others
	Kaurenoic acid (kaurenoate) has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level. Kaurenoic acid exerts a uterine relaxant effect acting principally through calcium blockade and in part,...		Others
T4845	L-Lactic acid	2-HYDROXYPROPIONIC ACID,L-(+)-Lactic acid,(S)-2-Hydroxypropanoic acid	Endogenous Metabolite , Antibacterial , Antibiotic
	L-Lactic acid ((S)-2-Hydroxypropanoic acid) is a natural product produced by the anaerobic glycolysis of pyruvic acid. L-Lactic acid is a sensitive indicator of tissue hypoxia and can be used as a hemodynamic indicator i...		Endogenous Metabolite , Antibacterial , Antibiotic
T3S0870	Paederosidic acid methyl ester		ATPase , Potassium Channel , NO Synthase
	Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.		ATPase , Potassium Channel , NO Synthase
T7774	A2793		Potassium Channel
	A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 μM. It is more selective for TRESK, and relatively weaker for TREK-1 and TALK-1.		Potassium Channel
T29067L	Upacicalcet HCl	Upacicalcet HCl(1333218-50-0 Free base)	CaSR
	Upacicalcet HCl is an intravesical calcium mimetic that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on calcium-sensitive receptors in parathyroid cell membranes, thereby lowering PTH levels ...		CaSR
T6301	Tosedostat	CHR-2797	Aminopeptidase , AChR
	Tosedostat (CHR-2797) is an orally bioavailable inhibitor of the M1 family of aminopeptidases with potential antineoplastic activity. Tosedostat is converted intracellularly into a poorly membrane-permeable active metabo...		Aminopeptidase , AChR
T5219	L-Alloisoleucine	L-allo-Isoleucine,(3R)-LS-Isoleucine,L(+)-Alloisoleucine	Others , Endogenous Metabolite
	L-Alloisoleucine (L-allo-Isoleucine) is a branched chain amino acid and is a stereoisomer of L-isoleucine. It is a common constituent of human plasma (albeit at low levels). L-alloisoleucine is produced as a byproduct of...		Others , Endogenous Metabolite
T6474	Divalproex Sodium	Valproate semisodium,Epival	HDAC
	Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzyme...		HDAC
TCS0102	Pulegone	(+)-Pulegone	Calcium Channel , Endogenous Metabolite , TRP/TRPV Channel
	1. Pulegone ((+)-Pulegone) has cytotoxicity followed by regenerative cell proliferation is the MOA for Pulegone-induced urothelial tumors in female rats. 2. Pulegone induces a verapamil-sensitive psychostimulant effect t...		Calcium Channel , Endogenous Metabolite , TRP/TRPV Channel
T7057	Methylstat		Histone Demethylase , Others
	Methylstat is a methyl ester prodrug of a Jumonji C domain-containing histone demethylase (JMJD) inhibitor that has favorable cell permeability. The free acid of methylstat inhibits JMJD2A, JMJD2C, JMJD2E, PHF8, and JMJD...		Histone Demethylase , Others
T21831	UCM05	G28UCM	Fatty Acid Synthase
	UCM05 (G28UCM) is a potent inhibitor of fatty acid synthase (FASN) with efficacy against HER2+ breast cancer xenografts, including in cell lines resistant to anti-HER2 drugs [1]. Additionally, it functions as an inhibito...		Fatty Acid Synthase
T22640	CCMQ		Others
	inhibits [3H]-homoquinolinic acid binding to non-NMDA sensitive sites		Others
T38735	(2-Hydroxyethoxy)acetic acid	β-hydroxyethoxyacetic acid,HEAA
	(2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the primary urinary metabolite of 1,4-Dioxane. It serves as a dependable and sensitive short-term biomarker in urine.
T19020	L-ANAP		Others
	L-ANAP is a polarity-sensitive and genetically encodable fluorescent unnatural amino acid.		Others
T19021	L-ANAP hydrochloride (1313516-26-5 free base)	L-ANAP hydrochloride	Others
	L-ANAP hydrochloride is a polarity-sensitive and genetically encodable fluorescent unnatural amino acid.		Others