Powder: -20°C for 3 years | In solvent: -80°C for 1 year
L-Lactic acid ((S)-2-Hydroxypropanoic acid) is a natural product produced by the anaerobic glycolysis of pyruvic acid. L-Lactic acid is a sensitive indicator of tissue hypoxia and can be used as a hemodynamic indicator in critically ill patients.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | In stock | $ 41.00 | |
1 g | In stock | $ 48.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 45.00 |
Description | L-Lactic acid ((S)-2-Hydroxypropanoic acid) is a natural product produced by the anaerobic glycolysis of pyruvic acid. L-Lactic acid is a sensitive indicator of tissue hypoxia and can be used as a hemodynamic indicator in critically ill patients. |
In vitro |
METHODS: Mouse CD4+CD25-T cells were treated with low-glucose medium containing L-Lactic acid (5-20 mM), and Teff proliferation was detected by Flow cytometry. RESULTS: L-Lactic acid had a sustained inhibitory effect on T cell proliferation, and apoptosis-independent effect. [1] METHODS: T cells were cultured in medium containing L-Lactic acid (20 mM), and ROS levels were measured using ROS and superoxide detection assay kits. RESULTS: A significant reduction in ROS and O2- production was observed in L-Lactic acid-treated T cells. [2] |
In vivo |
METHODS: To study its effect on swimming endurance, L-Lactic acid (25-50 mg/kg in 0.9% NaCl) was administered intraperitoneally to ICR mice. RESULTS: L-Lactic acid enhanced the swimming endurance of mice, and the effect was dose-dependent. [3] METHODS: To investigate the effect on endotoxemia, L-Lactic acid (80 mg/kg) was intraperitoneally injected into mice, and 20 h later, a lethal dose of LPS (25 mg/kg) was intraperitoneally injected into mice to induce infectious shock. RESULTS: L-Lactic acid significantly inhibited LPS-induced cytokine induction in mice following endotoxemia.L-Lactic acid treatment decreased glucose uptake and lactate output during LPS stimulation. [4] |
Synonyms | 2-HYDROXYPROPIONIC ACID, L-(+)-Lactic acid, (S)-2-Hydroxypropanoic acid |
Molecular Weight | 90.08 |
Formula | C3H6O3 |
CAS No. | 79-33-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (1387.66 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
L-Lactic acid 79-33-4 Metabolism Microbiology/Virology Endogenous Metabolite Antibacterial Antibiotic Inhibitor inhibit 2-HYDROXYPROPIONIC ACID LLactic acid L Lactic acid L-(+)-Lactic acid 2-Hydroxypropanoic acid (S)-2-Hydroxypropanoic acid Bacterial inhibitor