acetyl-coa — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T37958	Acetyl Coenzyme A trisodium	Acetyl-CoA trisodium	OXPHOS , Endogenous Metabolite , Autophagy
	Acetyl Coenzyme A trisodium (Acetyl-CoA trisodium) is an important compound in glucose metabolism and lipid metabolism and is involved in the tricarboxylic acid cycle.		OXPHOS , Endogenous Metabolite , Autophagy
T3510	Olumacostat Glasaretil		Acetyl-CoA Carboxylase
	Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.		Acetyl-CoA Carboxylase
TQ0243	ND-646		Acetyl-CoA Carboxylase
	ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively)		Acetyl-CoA Carboxylase
T4380	Ac-CoA Synthase Inhibitor1	ACSS2 inhibitor	RSV , Fatty Acid Synthase
	Ac-CoA Synthase Inhibitor1 (ACSS2 inhibitor) is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2).		RSV , Fatty Acid Synthase
T7163	PF-05175157		Acetyl-CoA Carboxylase
	PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, respectively		Acetyl-CoA Carboxylase
T5046	Haloxyfop	Haloxyfop Acid,(±)-Haloxyfop	Others , Acetyl-CoA Carboxylase
	(±)-Haloxyfop (Haloxyfop Acid) is a herbicide.		Others , Acetyl-CoA Carboxylase
T3988	TOFA	MDL14514,RMI14514	Acetyl-CoA Carboxylase
	TOFA (MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA).		Acetyl-CoA Carboxylase
T14991	CMS-121	CMS121	Acetyl-CoA Carboxylase
	CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM). CMS-121 shows strong neuroprotect...		Acetyl-CoA Carboxylase
T1889	CP-640186	CP 640186	Acetyl-CoA Carboxylase
	CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186(CP 640186) is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.		Acetyl-CoA Carboxylase
T72180	Acetyl-CoA Carboxylase-IN-1
	Acetyl-CoA Carboxylase-IN-1 is a potent inhibitor of acetyl-CoA carboxylase (ACC), exhibiting an inhibition concentration (IC50) of less than 5 nM. This compound also displays antibacterial activity.
T3622	CP-640186 hydrochloride	CP 640186 HCl	Acetyl-CoA Carboxylase
	CP-640186 hydrochloride (CP 640186 HCl) is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM); with higher metabolic stabilit...		Acetyl-CoA Carboxylase
T7184	Firsocostat	ND-630,NDI-010976,GS-0976	Acetyl-CoA Carboxylase
	Firsocostat (GS-0976) is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)		Acetyl-CoA Carboxylase
T9102	WM-3835		Apoptosis , Histone Methyltransferase , Histone Acetyltransferase
	WM-3835 is a novel and high-specific small molecule inhibitor of Lysine Acetyltransferase 7 (KAT7, MYST2, HBO1) , able to potently suppressed OS cell proliferation and migration, and leads to apoptosis activation.
T5213	Acetyl phosphate(lithium potassium)	Lithium potassium acetyl phosphate,Acetylphosphoric acid	Others , Endogenous Metabolite
	Acetyl phosphate lithium potassium (Lithium potassium acetyl phosphate) is a compound involved in taurine and hypotaurine metabolism as well as pyruvate metabolism. Acetyl phosphate lithium potassiu is generated from sul...		Others , Endogenous Metabolite
T9209	PF-05221304	STAT5 Inhibitor III,NSC 170984,R 6238,,Clesacostat	Acetyl-CoA Carboxylase
	PF-05221304 (NSC-170984) is an orally active, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), a rate-limiting enzymes for fatty acid synthesis.		Acetyl-CoA Carboxylase
T5267	N-Acetyl-L-glutamic acid	Ac-L-Glu-OH,N-Acetylglutamic acid	Others , Endogenous Metabolite
	N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) (NAcGlu) is an acetylated amino acid. NAcGlu is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetyl glutamate synthase (NAGS). NAcGlu activates carbamoyl phospha...		Others , Endogenous Metabolite
T9732	VY-3-135		Fatty Acid Synthase
	VY-3-135 is a metastasis inhibitor and an acetyl-CoA synthetase 2 (ACSS2) modulator.		Fatty Acid Synthase
T73350	BAY-3827		Acyltransferase , AMPK
	BAY-3827 is a potent and selective AMPK inhibitor with potential antitumor activity, showing antiproliferative activity in an androgen-dependent prostate cancer model. BAY-3827 inhibits the phosphorylation of acetyl CoA ...		Acyltransferase , AMPK
T13979	(S)-3-Hydroxybutanoic acid	L-β-Hydroxybutyric acid,(S)-β-Hydroxybutanoic acid,L-(+)-3-Hydroxybutyric acid	Endogenous Metabolite
	(S)-3-Hydroxybutanoic acid (L-(+)-3-Hydroxybutyric acid) is a normal human metabolite that has been found elevated in geriatric patients remitting from depression. (S)-3-Hydroxybutanoic acid is synthesized in the liver f...		Endogenous Metabolite
T5287	N-Acetyl-L-aspartic acid	AC-ASP-OH,N-Acetylaspartic acid	Others , Endogenous Metabolite
	N-Acetyl-L-aspartic acid (AC-ASP-OH) is a derivative of aspartic acid. It is the second most concentrated molecule in the brain after the amino acid glutamate. It is synthesized in neurons from the amino acid aspartate a...		Others , Endogenous Metabolite