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N-Acetyl-L-aspartic acid

Catalog No. T5287   CAS 997-55-7
Synonyms: AC-ASP-OH, N-Acetylaspartic acid

N-Acetyl-L-aspartic acid (AC-ASP-OH) is a derivative of aspartic acid. It is the second most concentrated molecule in the brain after the amino acid glutamate. It is synthesized in neurons from the amino acid aspartate and acetyl coenzyme A (acetyl CoA). The various functions served by N-Acetyl-L-aspartic acid (AC-ASP-OH) are still under investigation, but the primary proposed functions include (1) acting as a neuronal osmolyte that is involved in fluid balance in the brain, (2) serving as a source of acetate for lipid and myelin synthesis in oligodendrocytes (the glial cells that myelinate neuronal axons), (3) serving as a precursor for the synthesis of the important dipeptide neurotransmitter N-acetylaspartylglutamate (NAAG), and (4) playing a potential role in energy production from the amino acid glutamate in neuronal mitochondria.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
N-Acetyl-L-aspartic acid Chemical Structure
N-Acetyl-L-aspartic acid, CAS 997-55-7
Pack Size Availability Price/USD Quantity
100 mg In stock $ 41.00
200 mg In stock $ 59.00
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Purity: 99.52%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description N-Acetyl-L-aspartic acid (AC-ASP-OH) is a derivative of aspartic acid. It is the second most concentrated molecule in the brain after the amino acid glutamate. It is synthesized in neurons from the amino acid aspartate and acetyl coenzyme A (acetyl CoA). The various functions served by N-Acetyl-L-aspartic acid (AC-ASP-OH) are still under investigation, but the primary proposed functions include (1) acting as a neuronal osmolyte that is involved in fluid balance in the brain, (2) serving as a source of acetate for lipid and myelin synthesis in oligodendrocytes (the glial cells that myelinate neuronal axons), (3) serving as a precursor for the synthesis of the important dipeptide neurotransmitter N-acetylaspartylglutamate (NAAG), and (4) playing a potential role in energy production from the amino acid glutamate in neuronal mitochondria.
Synonyms AC-ASP-OH, N-Acetylaspartic acid
Molecular Weight 175.14
Formula C6H9NO5
CAS No. 997-55-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 3.33 mg/mL (19.03 mM)

TargetMolReferences and Literature

1. Sreekumar A, et al. Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009 Feb 12;457(7231):910-4.

Related compound libraries

This product is contained In the following compound libraries：
Human Endogenous Metabolite Library Human Metabolite Library RO5 Drug-like Natural Product Library Natural Product Library for HTS Natural Product Library Human Endogenous Metabolite Compound Library Plus Mouse Metabolite Compound Library Gut Microbial Metabolite Library

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Keywords

N-Acetyl-L-aspartic acid 997-55-7 Metabolism Others Endogenous Metabolite N Acetyl L aspartic acid NAcetylLaspartic acid AC-ASP-OH Inhibitor N-Acetylaspartic acid inhibit inhibitor

 

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