Search Result

Search Results for " vegf-c "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T8496	MAZ51		Apoptosis , VEGFR
	MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.		Apoptosis , VEGFR
T9929	Ramucirumab		VEGFR
	Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.		VEGFR
T72924	VEGFR-3-IN-1		VEGFR
	VEGFR-3-IN-1 is a novel potent and selective VEGFR3 inhibitor with an IC50 of 110.4 nM.VEGFR-3-IN-1 possesses antitumor activity, inactivates the VEGFR3 signaling pathway, and inhibits the proliferation and migration of ...		VEGFR
T3708	BP-1-102		STAT
	BP-1-102 is an orally active, effective and specific STAT3 inhibitor. BP-1-102 binds Stat3 (Kd: 504 nM), then blocks Stat3-phosphotyrosine (pTyr) peptide interactions and Stat3 activation (4-6.8 μM), and selectively inhi...		STAT
T28899	T-1840383
	T-1840383 is an inhibitor of VEGF-induced VEGFR-2 phosphorylation and HGF-induced c-Met phosphorylation in vascular endothelial cells and cancer epithelial cells.
T71930	APKC-I
	aPKC-I is an inhibitor of atypical protein kinase C (aPKC ) which inhibits both PKCζ and PKCι with high specificity and prevents VEGF-induced endothelial permeability in cell culture and in vivo, thereby blocking ischemi...
T80595	Conbercept	KH902	VEGFR
	Conbercept (KH902) is a fusion protein comprising the second immunoglobulin C-like domain of FLT1 and the third and fourth immunoglobulin C-like domains of KDR, linked to the Fc fragment of IGHG1. This monoclonal antibod...		VEGFR
T71204	Apatinib HC	Rivoceranib HCl,YN-968D1 HCl
	Apatinib, also known as Rivoceranib and YN-968D1, is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. The free-base form is also known...
T21387	Nafoxidine HCl（1845-11-0 Free base）	PNU-0011100,PNU0011100,CP5600,CP 5600,CP-5600,PNU 0011100,Nafoxidine HCl
	Nafoxidine is a partial estrogen antagonist. It inhibits angiogenesis in some tissues by blocking the effects of VEGF and FGF; paradoxically, it may enhance angiogenesis in uterine tissue. Nafoxidine also induces calcium...
T69354	Enzastaurin 2HCl
	Enzastaurin 2HCl, also known as DB-102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, Enzastaurin 2HCl selectively inhibits protein ki...
T74422	Sozinibercept
	Sozinibercept (OPT 302; VGX-300) is a soluble form of Vascular Endothelial Growth Factor Receptor-3 (VEGFR-3) that potently inhibits the activity of Vascular Endothelial Growth Factor-C and -D (VEGF-C/D), key proangiogen...
T71853	Enzastaurin HCl
	Enzastaurin HCl, also known as DB-102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, Enzastaurin HCl selectively inhibits protein kina...
T37079	VEGFR2 Kinase Inhibitor II
	Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms...
T27033	CKD-712	CKD 712,CKD712
	CKD-712 is a nuclear factor NF-kappa B inhibitor. CKD-712 suppressed MMP-9, but not MMP-2 and other NF-κB-regulated proteins involved in cancer metastasis such as VEGF. CKD-712 induced cell cycle arrest at G2M phase by s...
T61604	PKC-IN-4
	PKC-IN-4 (compound 7l) is a highly potent and orally active inhibitor of atypical protein kinase C (aPKC), exhibiting an IC 50 value of 0.52 μM. In vitro studies have demonstrated that PKC-IN-4 effectively suppresses NF-...
T71180	Oglufanide disodium
	Oglufanide disodium is t he disodium salt of a synthetic form of a naturally-occurring dipeptide consisting of L-glutamic acid and L-tryptophan with potential antiangiogenic and potential immunomodulating activities. Ogl...
T83741	S7 TFA	Leu-Ser-Leu-Iso-Thr-Arg-Leu-OH
	S7, a peptide antagonist of the IL-6 receptor, concentration-dependently inhibits IL-6 binding to its receptor. At 50 µM, S7 suppresses IL-6-triggered elevations in VEGF levels within C-33 A cervical cancer cells and RPM...
T73516	EVT801
	EVT801 is an orally active, selective VEGFR-3 inhibitor (IC 50 = 11 nM) with demonstrated antitumor properties. It effectively suppresses VEGF-C-induced human endothelial cell proliferation and tumor (lymphatic) angiogen...
T36379	Halometasone
	Halometasone is a synthetic corticosteroid.1,2Formulations containing halometasone have been used in the treatment of psoriasis vulgaris and eczematous dermatoses. 1.de la Brassine, M., Kint, A., Lachapelle, J.M., et al....

Compounds

MAZ51

T8496

Synonym:

Target: Apoptosis, VEGFR

Synonym: Rivoceranib HCl,YN-968D1 HCl

Target:

Nafoxidine HCl（1845-11-0 Free base）

T21387

Synonym: PNU-0011100,PNU0011100,CP5600,CP 5600,CP-5600,PNU 0011100,Nafoxidine HCl

VEGFR2 Kinase Inhibitor II

Synonym: CKD 712,CKD712

Synonym: Leu-Ser-Leu-Iso-Thr-Arg-Leu-OH

Cat No.	Product Name	Synonyms	Targets
T3S0335	Soyasaponin Bb	Soyasaponin I	NF-κB , Caspase
	1. Soyasaponin Bb (Soyasaponin I) can suppress Eca-976 cell growth, reverse effects on over expression of c-met, VEGF, and induce cell apoptosis through inhibiting HDAC1-NF-kappaB and activating PETEN and caspase-3 signa...		NF-κB , Caspase
T3S2344	β,β-Dimethylacrylshikonin	Dimethylacrylshikonin,β, β-Dimethylacrylshikonin	ERK , HIF/HIF Prolyl-Hydroxylase
	1. β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significant...		ERK , HIF/HIF Prolyl-Hydroxylase

Natural Products

Soyasaponin Bb

T3S0335

Synonym: Soyasaponin I

Target: NF-κB, Caspase

β,β-Dimethylacrylshikonin

T3S2344

Synonym: Dimethylacrylshikonin,β, β-Dimethylacrylshikonin

Target: ERK, HIF/HIF Prolyl-Hydroxylase

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01007	VEGFC Protein, Human, Recombinant (His)	Human	HEK293
	Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei...
TMPY-01008	VEGFD Protein, Human, Recombinant (His)	Human	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPK-01044	VEGFC Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet...
TMPK-01043	VEGFC Protein, Human, Recombinant (His & Avi)	Human	HEK293
	the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet...
TMPY-03150	VEGFD Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPY-02589	VEGFD Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPY-03156	VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, His)	Mouse,Rat	HEK293
	Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei...
TMPJ-00865	VEGF121 Protein, Human, Recombinant (His)	Human	Human Cells
	Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PD...
TMPY-01936	VEGFR3/FLT4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-02361	VEGFR2/KDR Protein, Human, Recombinant (His)	Human	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-04976	PDGFC Protein, Mouse, Recombinant (His)	Mouse	Yeast
	PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-02836	MFGE8 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	MFG-E8, also known as lactadherin and MFGE8, contains 1 EGF-like domain and 2 F5/8 type C domains. It also contains phosphatidylserine (PS) binding domain, as well as an Arginine-Glycine-Aspartic acid motif, which enable...
TMPY-00891	Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)	Human	HEK293
	Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-00356	Neuropilin-1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-05740	Neuropilin-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-02367	Neuropilin-1 Protein, Human, Recombinant (isoform b, His)	Human	HEK293
	Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-01915	DLL1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Delta-like protein 1(DLL1), also known as Delta1, a single-pass type I membrane protein which contains one DSL domain and eight EGF-like domains, acts as a ligand for Notch receptors, and positively regulates T-cell deve...
TMPY-01379	DLL1 Protein, Human, Recombinant (His)	Human	HEK293
	Delta-like protein 1(DLL1), also known as Delta1, a single-pass type I membrane protein which contains one DSL domain and eight EGF-like domains, acts as a ligand for Notch receptors, and positively regulates T-cell deve...
TMPY-05833	DLL1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Delta-like protein 1(DLL1), also known as Delta1, a single-pass type I membrane protein which contains one DSL domain and eight EGF-like domains, acts as a ligand for Notch receptors, and positively regulates T-cell deve...
TMPY-03155	VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, hFc)	Mouse,Rat	HEK293
	Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei...
TMPK-00822	VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled	Human	HEK293
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPY-03200	VEGFD Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPJ-00414	VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His & Avi), Biotinylated	Human	Human Cells
	Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in a number of fundamental biological processes such as the re...
TMPY-06620	VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPJ-00593	VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His)	Human	Human Cells
	Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in a number of fundamental biological processes such as the re...
TMPY-01069	VEGFR3/FLT4 Protein, Human, Recombinant (hFc)	Human	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-01937	VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-05382	VEGFR2/KDR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-04796	VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His)	Human	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-02858	VEGFR2/KDR Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-02736	VEGFR2/KDR Protein, Mouse, Recombinant (His)	Mouse	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-04530	VEGFR2/KDR Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-04794	VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc)	Human	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-04795	VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His)	Human	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-05657	VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated	Human	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-03202	VEGFR2/KDR Protein, Rat, Recombinant (hFc)	Rat	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-02678	VEGFR2/KDR Protein, Rat, Recombinant (His)	Rat	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-01044	VEGFR2/KDR Protein, Human, Recombinant (hFc)	Human	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-04924	VEGFR2/KDR Protein, Mouse, Recombinant (His), Biotinylated	Mouse	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-05610	VEGFR2/KDR Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-04940	VEGFR2/KDR Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-04802	VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc)	Human	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-02815	PDGFC Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPJ-00802	THBS1 Protein, Human, Recombinant (His)	Human	Human Cells
	Thrombospondin-1 (TSP-1) is a 150-180kDa calcium-sensitive protein that is secreted as a disulfide-linked homotrimer. TSP-1 regulates a wide range of cellular functions including their interactions with other cells and w...
TMPY-02251	PDGFC Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-00269	PDGFC Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293
	PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-00898	PDGFC Protein, Human, Recombinant (hFc)	Human	HEK293
	PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-05235	MFGE8 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Baculovirus-Insect Cells
	MFG-E8, also known as lactadherin and MFGE8, contains 1 EGF-like domain and 2 F5/8 type C domains. It also contains phosphatidylserine (PS) binding domain, as well as an Arginine-Glycine-Aspartic acid motif, which enable...
TMPY-05519	Neuropilin-1 Protein, Mouse, Recombinant (mFc)	Mouse	HEK293
	Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-03933	Neuropilin-1 Protein, Cynomolgus, Recombinant	Cynomolgus	HEK293
	Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
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